Annotation Detail for PKD1
Basic Information Top
| Gene Symbol: | PKD1 ( PBP,Pc-1,TRPP1 ) |
|---|---|
| Gene Full Name: | polycystic kidney disease 1 (autosomal dominant) |
| Band: | 16p13.3 |
| Quick Links | Entrez ID:5310; OMIM: 601313; Uniprot ID:PKD1_HUMAN; ENSEMBL ID: ENSG00000008710; HGNC ID: 9008 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.75813
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 7 / 70761 | 98 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 28 / 564012 | 49 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 99 / 1939121 | 51 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 13 / 106883 | 121 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 7 / 95842 | 73 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 205 / 3360307 | 61 | |
| ovarian tumor | 7 / 76682 | 91 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 12 / 124949 | 96 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 101 / 1100989 | 91 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 12 / 215722 | 55 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 14 / 211054 | 66 | |
| heart | 2 / 89626 | 22 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 17 / 336974 | 50 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 |  |
| nerve | 0 / 15768 | 0 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 15 / 214812 | 69 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 18 / 210574 | 85 | |
| spleen | 6 / 53952 | 111 | |
| stomach | 4 / 96619 | 41 | |
| testis | 14 / 330442 | 42 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202327_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.4 | |
| Adipocyte | 4.45 | |
| AdrenalCortex | 4.85 | |
| Adrenalgland | 3.8 | |
| Amygdala | 4.75 | |
| Appendix | 4.55 | |
| AtrioventricularNode | 3.55 | |
| BDCA4+_DentriticCells | 4.95 | |
| Bonemarrow | 4.5 | |
| BronchialEpithelialCells | 4.35 | |
| CD105+_Endothelial | 4.6 | |
| CD14+_Monocytes | 4.75 | |
| CD19+_BCells(neg._sel.) | 4.95 | |
| CD33+_Myeloid | 5.8 | |
| CD34+ | 5.75 | |
| CD4+_Tcells | 4.9 | |
| CD56+_NKCells | 5.4 | |
| CD71+_EarlyErythroid | 4.25 | |
| CD8+_Tcells | 4.3 | |
| CardiacMyocytes | 5.85 | |
| Caudatenucleus | 4.15 | |
| Cerebellum | 4.25 | |
| CerebellumPeduncles | 5.15 | |
| CiliaryGanglion | 3.25 | |
| CingulateCortex | 4.6 | |
| Colorectaladenocarcinoma | 4.55 | |
| DorsalRootGanglion | 3.5 | |
| FetalThyroid | 4.4 | |
| Fetalbrain | 4.5 | |
| Fetalliver | 3.9 | |
| Fetallung | 3.6 | |
| GlobusPallidus | 3.35 | |
| Heart | 5.75 | |
| Hypothalamus | 4.8 | |
| Kidney | 3.75 | |
| Leukemia_chronicMyelogenousK-562 | 4.1 | |
| Leukemia_promyelocytic-HL-60 | 4 | |
| Leukemialymphoblastic(MOLT-4) | 3.6 | |
| Liver | 6 | |
| Lung | 4.9 | |
| Lymphnode | 3.8 | |
| Lymphoma_burkitts(Daudi) | 5.75 | |
| Lymphoma_burkitts(Raji) | 6.35 | |
| MedullaOblongata | 4.15 | |
| OccipitalLobe | 4 | |
| OlfactoryBulb | 3.55 | |
| Ovary | 3.5 | |
| Pancreas | 3.6 | |
| PancreaticIslet | 5.15 | |
| ParietalLobe | 4.8 | |
| Pituitary | 5.3 | |
| Placenta | 4.55 | |
| Pons | 5.7 | |
| PrefrontalCortex | 5.65 | |
| Prostate | 5.25 | |
| Salivarygland | 3.65 | |
| SkeletalMuscle | 5.4 | |
| Skin | 3.5 | |
| SmoothMuscle | 5.1 | |
| Spinalcord | 4.8 | |
| SubthalamicNucleus | 4.15 | |
| SuperiorCervicalGanglion | 5.2 | |
| TemporalLobe | 4.75 | |
| Testis | 3.85 | |
| TestisGermCell | 3.7 | |
| TestisIntersitial | 3.75 | |
| TestisLeydigCell | 4.4 | |
| TestisSeminiferousTubule | 3.85 | |
| Thalamus | 4.6 | |
| Thymus | 3.55 | |
| Thyroid | 5.6 | |
| Tongue | 4.5 | |
| Tonsil | 4.35 | |
| Trachea | 3.8 | |
| TrigeminalGanglion | 4.65 | |
| Uterus | 3.65 | |
| UterusCorpus | 4.05 | |
| WholeBlood | 4.9 | |
| Wholebrain | 3.8 | |
| colon | 4.5 | |
| pineal_day | 5.64 | |
| pineal_night | 5.52 | |
| retina | 5.425 | |
| small_intestine | 4.35 | |
- Probe name: A_24_P916006
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.78 ± 0.51 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.09 ± 0.37 | |
| Basal Part of Pons | 5.5 ± 0.63 | |
| Cerebellar Cortex | 5.95 ± 0.42 | |
| Cerebellar Nuclei | 4.76 ± 0.46 | |
| Claustrum | 5.9 ± 0.92 | |
| Epithalamus | 4.65 ± 0.62 | |
| Frontal Lobe | 5.03 ± 0.64 | |
| Globus Pallidus | 4.62 ± 0.44 | |
| Hypothalamus | 4.76 ± 0.5 | |
| Insula | 4.9 ± 0.68 | |
| Limbic Lobe | 5.64 ± 0.73 | |
| Mesencephalon | 5.15 ± 0.64 | |
| Myelencephalon | 5.29 ± 0.69 | |
| Occipital Lobe | 6 ± 0.69 | |
| Parietal Lobe | 5.28 ± 0.48 | |
| Pontine Tegmentum | 5.03 ± 0.66 | |
| Striatum | 4.84 ± 0.59 | |
| Subthalamus | 4.18 ± 0.37 | |
| Temporal Lobe | 5.18 ± 0.62 | |
| Thalamus | 5.07 ± 0.67 | |
| White Matter | 4.86 ± 0.66 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pkd1 | CB | Cerebellum | 100 | |
| 100 | | |||
| Pkd1 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Pkd1 | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Pkd1 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Pkd1 | HY | Hypothalamus | 100 | |
| 100 | | |||
| Pkd1 | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Pkd1 | MB | Midbrain | 100 | |
| 100 | | |||
| Pkd1 | MY | Medulla | 90.86 | |
| 97.8 | | |||
| Pkd1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Pkd1 | P | Pons | 95.38 | |
| 92.94 | | |||
| Pkd1 | PAL | Pallidum | 100 | |
| 100 | | |||
| Pkd1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Pkd1 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Pkd1 | STR | Striatum | 100 | |
| 100 | | |||
| Pkd1 | STRd | Striatum dorsal region | 100 | |
| 100 | | |||
| Pkd1 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Pkd1 | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PKD1_HUMAN_3831 | 15 | 3831 | 3845 | DRLRFLQLHNWLDNR | PRIDE |