AutismKB 2.0

Annotation Detail for PLAUR


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Basic Information Top
Gene Symbol:PLAUR ( CD87,UPAR,URKR )
Gene Full Name: plasminogen activator, urokinase receptor
Band: 19q13
Quick LinksEntrez ID:5329; OMIM: 173391; Uniprot ID:UPAR_HUMAN; ENSEMBL ID: ENSG00000011422; HGNC ID: 9053
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus10 / 56401217
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult159 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma16 / 82823193
colorectal tumor16 / 114246140
esophageal tumor2 / 17290115
gastrointestinal tumor8 / 11936967
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia8 / 9584283
liver tumor7 / 9635972
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal124 / 336030736
ovarian tumor12 / 76682156
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood19 / 123478153
bone8 / 71655111
bone marrow2 / 4880140
brain5 / 11009894
cervix3 / 4817162
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus2 / 2020998
eye6 / 21105428
heart0 / 896260 
intestine28 / 234472119
kidney7 / 21177733
larynx2 / 2414582
liver11 / 20774352
lung67 / 336974198
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth0 / 670520 
muscle8 / 10771574
nerve0 / 157680 
ovary18 / 102051176
pancreas22 / 214812102
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin21 / 21057499
spleen1 / 5395218
stomach7 / 9661972
testis0 / 3304420 
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus6 / 23287825
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214866_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.6
Adipocyte34.6
AdrenalCortex83.75
Adrenalgland35.8
Amygdala34.75
Appendix56.65
AtrioventricularNode69.6
BDCA4+_DentriticCells22.85
Bonemarrow45.5
BronchialEpithelialCells41.6
CD105+_Endothelial27
CD14+_Monocytes59.7
CD19+_BCells(neg._sel.)18.25
CD33+_Myeloid43.95
CD34+20.85
CD4+_Tcells13.1
CD56+_NKCells29.4
CD71+_EarlyErythroid33.8
CD8+_Tcells22.5
CardiacMyocytes55
Caudatenucleus26.55
Cerebellum35.75
CerebellumPeduncles60.35
CiliaryGanglion36.2
CingulateCortex48.95
Colorectaladenocarcinoma63.4
DorsalRootGanglion49.2
FetalThyroid47
Fetalbrain31.9
Fetalliver32.15
Fetallung23.3
GlobusPallidus42.7
Heart99.15
Hypothalamus35.1
Kidney42.05
Leukemia_chronicMyelogenousK-56233.5
Leukemia_promyelocytic-HL-6029.05
Leukemialymphoblastic(MOLT-4)30.4
Liver75.25
Lung74.35
Lymphnode31.6
Lymphoma_burkitts(Daudi)69.45
Lymphoma_burkitts(Raji)51.35
MedullaOblongata35
OccipitalLobe31.4
OlfactoryBulb27.45
Ovary42.25
Pancreas64.95
PancreaticIslet45.45
ParietalLobe52.5
Pituitary52
Placenta32.05
Pons62.15
PrefrontalCortex32.35
Prostate43.2
Salivarygland30.25
SkeletalMuscle86
Skin54
SmoothMuscle77.7
Spinalcord41.8
SubthalamicNucleus42.55
SuperiorCervicalGanglion112.2
TemporalLobe55.45
Testis30.5
TestisGermCell32.35
TestisIntersitial30.65
TestisLeydigCell43.5
TestisSeminiferousTubule32.95
Thalamus38.55
Thymus35.55
Thyroid40.15
Tongue71.95
Tonsil62.45
Trachea34.25
TrigeminalGanglion64.85
Uterus28.85
UterusCorpus39.4
WholeBlood98.15
Wholebrain22.65
colon27.2
pineal_day25.58
pineal_night25.54
retina37.075
small_intestine24.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14476_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.23 ± 0.72
Basal Forebrain4.01 ± 0.36
Basal Part of Pons4.52 ± 0.44
Cerebellar Cortex3.86 ± 0.5
Cerebellar Nuclei4.34 ± 0.52
Claustrum4.49 ± 0.67
Epithalamus4.01 ± 0.49
Frontal Lobe4.01 ± 0.53
Globus Pallidus4.78 ± 0.48
Hypothalamus3.83 ± 0.85
Insula3.86 ± 0.48
Limbic Lobe4.21 ± 0.6
Mesencephalon4.04 ± 0.62
Myelencephalon4.23 ± 0.59
Occipital Lobe4.39 ± 0.75
Parietal Lobe4.06 ± 0.59
Pontine Tegmentum3.86 ± 0.73
Striatum4.34 ± 0.68
Subthalamus3.23 ± 0.79
Temporal Lobe4 ± 0.61
Thalamus4.4 ± 0.51
White Matter5.4 ± 0.47
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010376 7 132 138 HQSLQCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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