AutismKB 2.0

Annotation Detail for PLCD1


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Basic Information Top
Gene Symbol:PLCD1 ( - )
Gene Full Name: phospholipase C, delta 1
Band: 3p22.2
Quick LinksEntrez ID:5333; OMIM: 602142; Uniprot ID:PLCD1_HUMAN; ENSEMBL ID: ENSG00000187091; HGNC ID: 9060
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus36 / 56401263
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor15 / 26384556
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal264 / 336030778
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow1 / 4880120
brain79 / 110098971
cervix1 / 4817120
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine12 / 23447251
kidney10 / 21177747
larynx0 / 241450 
liver2 / 2077439
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth8 / 67052119
muscle3 / 10771527
nerve1 / 1576863
ovary6 / 10205158
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland0 / 201550 
skin7 / 21057433
spleen9 / 53952166
stomach1 / 9661910
testis72 / 330442217
thymus24 / 81131295
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord1 / 1368073
uterus16 / 23287868
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205125_at
Cell line Expression level Expression bar
721_B_lymphoblasts73.3
Adipocyte163.65
AdrenalCortex171.55
Adrenalgland140.5
Amygdala125.75
Appendix153.05
AtrioventricularNode141.85
BDCA4+_DentriticCells63.75
Bonemarrow169.4
BronchialEpithelialCells154.45
CD105+_Endothelial63.8
CD14+_Monocytes47.65
CD19+_BCells(neg._sel.)44.05
CD33+_Myeloid75.5
CD34+47.05
CD4+_Tcells125.2
CD56+_NKCells90.5
CD71+_EarlyErythroid82.15
CD8+_Tcells114.4
CardiacMyocytes195.5
Caudatenucleus143.8
Cerebellum246.95
CerebellumPeduncles201.85
CiliaryGanglion108.15
CingulateCortex241.15
Colorectaladenocarcinoma149.2
DorsalRootGanglion193.75
FetalThyroid150.75
Fetalbrain150.3
Fetalliver175.8
Fetallung129.15
GlobusPallidus146.3
Heart135.55
Hypothalamus174.05
Kidney190.65
Leukemia_chronicMyelogenousK-562166.65
Leukemia_promyelocytic-HL-60102.4
Leukemialymphoblastic(MOLT-4)112.2
Liver192.4
Lung171.25
Lymphnode142.4
Lymphoma_burkitts(Daudi)172
Lymphoma_burkitts(Raji)157
MedullaOblongata278.05
OccipitalLobe106.85
OlfactoryBulb155.75
Ovary138.1
Pancreas181
PancreaticIslet171.25
ParietalLobe228.1
Pituitary223.3
Placenta123.75
Pons210.45
PrefrontalCortex226.65
Prostate135.45
Salivarygland121.2
SkeletalMuscle198.2
Skin159.6
SmoothMuscle105.8
Spinalcord280.8
SubthalamicNucleus193.55
SuperiorCervicalGanglion393
TemporalLobe163.55
Testis315.3
TestisGermCell506
TestisIntersitial205.2
TestisLeydigCell246.65
TestisSeminiferousTubule294.2
Thalamus171.2
Thymus121.7
Thyroid126.9
Tongue192.6
Tonsil168
Trachea133.75
TrigeminalGanglion280.75
Uterus118.1
UterusCorpus112.95
WholeBlood145.9
Wholebrain110.8
colon172.95
pineal_day119.84
pineal_night92.82
retina243.775
small_intestine85.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P80739
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.3 ± 0.18
Basal Forebrain7.41 ± 0.29
Basal Part of Pons7.02 ± 0.21
Cerebellar Cortex6.9 ± 0.17
Cerebellar Nuclei7.02 ± 0.2
Claustrum6.83 ± 0.38
Epithalamus7.88 ± 0.27
Frontal Lobe7.18 ± 0.37
Globus Pallidus8.28 ± 0.38
Hypothalamus7.28 ± 0.31
Insula7.09 ± 0.33
Limbic Lobe7.02 ± 0.49
Mesencephalon7.36 ± 0.42
Myelencephalon7.33 ± 0.35
Occipital Lobe7.38 ± 0.34
Parietal Lobe7.26 ± 0.32
Pontine Tegmentum7.13 ± 0.41
Striatum7.65 ± 0.3
Subthalamus7.26 ± 0.07
Temporal Lobe7.01 ± 0.36
Thalamus7.41 ± 0.3
White Matter6.79 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plcd1CBCerebellum2.55
2.25
Plcd1CTXCerebral cortex1.87
1.27
Plcd1HIPHippocampal region5.08
3.11
Plcd1HPFHippocampal formation3.85
2.33
Plcd1HYHypothalamus7.18
4.82
Plcd1LSXLateral septal complex0.23
0.2
Plcd1MBMidbrain3.63
2.59
Plcd1MYMedulla9.3
7.03
Plcd1OLFOlfactory bulb2.33
2.54
Plcd1PPons8.44
6.12
Plcd1PALPallidum2.59
1.73
Plcd1RHPRetrohippocampal region1.72
1.24
Plcd1sAMYStriatum-like amygdalar nuclei3.64
2.76
Plcd1STRStriatum1.01
0.66
Plcd1STRdStriatum dorsal region0.55
0.35
Plcd1STRvStriatum ventral region1.6
0.82
Plcd1THThalamus2.61
1.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024825 20 187 206 ECDHSQTDSLEDEEIEAFYK Peptide Atlas
PLCD1_HUMAN_81 9 81 89 TEGLEKFAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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