AutismKB 2.0

Annotation Detail for PLCL1


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Basic Information Top
Gene Symbol:PLCL1 ( MGC126580,MGC138190,PLCE,PLCL,PLDL1,PRIP )
Gene Full Name: phospholipase C-like 1
Band: 2q33.1
Quick LinksEntrez ID:5334; OMIM: 600597; Uniprot ID:PLCL1_HUMAN; ENSEMBL ID: ENSG00000115896; HGNC ID: 9063
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart5 / 8962655
intestine0 / 2344720 
kidney6 / 21177728
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205934_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.9
Adipocyte9.75
AdrenalCortex12.6
Adrenalgland9
Amygdala27
Appendix14.3
AtrioventricularNode9.8
BDCA4+_DentriticCells8.85
Bonemarrow10.85
BronchialEpithelialCells9.2
CD105+_Endothelial9.95
CD14+_Monocytes11.25
CD19+_BCells(neg._sel.)9.8
CD33+_Myeloid13.9
CD34+11.35
CD4+_Tcells18.05
CD56+_NKCells11.6
CD71+_EarlyErythroid10
CD8+_Tcells9.75
CardiacMyocytes20.05
Caudatenucleus10.4
Cerebellum8.7
CerebellumPeduncles12.75
CiliaryGanglion9.1
CingulateCortex11.1
Colorectaladenocarcinoma9.55
DorsalRootGanglion9.9
FetalThyroid10.45
Fetalbrain10.55
Fetalliver8.7
Fetallung6.9
GlobusPallidus8.4
Heart17
Hypothalamus40.5
Kidney9.75
Leukemia_chronicMyelogenousK-5629.45
Leukemia_promyelocytic-HL-608.55
Leukemialymphoblastic(MOLT-4)7.6
Liver15.4
Lung10.85
Lymphnode8.6
Lymphoma_burkitts(Daudi)13.15
Lymphoma_burkitts(Raji)15.3
MedullaOblongata10.2
OccipitalLobe22.2
OlfactoryBulb8
Ovary7.6
Pancreas8.7
PancreaticIslet10.9
ParietalLobe13.85
Pituitary12
Placenta9.25
Pons10.55
PrefrontalCortex24.25
Prostate12.15
Salivarygland8.9
SkeletalMuscle17.3
Skin10.25
SmoothMuscle11.65
Spinalcord11.9
SubthalamicNucleus10.1
SuperiorCervicalGanglion18.85
TemporalLobe9.95
Testis8.25
TestisGermCell7.7
TestisIntersitial8.75
TestisLeydigCell10.7
TestisSeminiferousTubule8.25
Thalamus11.2
Thymus8.5
Thyroid13.75
Tongue11.6
Tonsil10.2
Trachea8.5
TrigeminalGanglion12.4
Uterus43.25
UterusCorpus10.85
WholeBlood11.35
Wholebrain18.2
colon10.65
pineal_day259.12
pineal_night303.78
retina25.8
small_intestine8.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P212688
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.05 ± 0.48
Basal Forebrain4.39 ± 0.35
Basal Part of Pons4.15 ± 0.3
Cerebellar Cortex4.09 ± 0.39
Cerebellar Nuclei5.44 ± 0.45
Claustrum3.93 ± 0.67
Epithalamus4.46 ± 0.64
Frontal Lobe4.49 ± 0.51
Globus Pallidus5.8 ± 0.38
Hypothalamus4.41 ± 0.71
Insula4.11 ± 0.69
Limbic Lobe4.3 ± 0.62
Mesencephalon4.73 ± 0.54
Myelencephalon4.59 ± 0.61
Occipital Lobe4.85 ± 0.63
Parietal Lobe4.46 ± 0.5
Pontine Tegmentum4.78 ± 0.65
Striatum5.32 ± 0.49
Subthalamus4.81 ± 0.1
Temporal Lobe4.41 ± 0.48
Thalamus4.84 ± 0.43
White Matter4.95 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plcl1CBCerebellum14.08
13.99
Plcl1CTXCerebral cortex24
16.07
Plcl1HIPHippocampal region30.58
39.37
Plcl1HPFHippocampal formation26.64
28.09
Plcl1HYHypothalamus19.68
13.64
Plcl1LSXLateral septal complex13.88
11.04
Plcl1MBMidbrain33.57
27.76
Plcl1MYMedulla49.81
45.42
Plcl1OLFOlfactory bulb28.85
19.06
Plcl1PPons42.97
35.38
Plcl1PALPallidum27.36
21.5
Plcl1RHPRetrohippocampal region20.5
13.96
Plcl1sAMYStriatum-like amygdalar nuclei13.93
8.38
Plcl1STRStriatum17.12
11.64
Plcl1STRdStriatum dorsal region19.67
13.65
Plcl1STRvStriatum ventral region10.47
6.39
Plcl1THThalamus24.6
18.33
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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