AutismKB 2.0

Annotation Detail for PLD1


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Basic Information Top
Gene Symbol:PLD1 ( - )
Gene Full Name: phospholipase D1, phosphatidylcholine-specific
Band: 3q26.31
Quick LinksEntrez ID:5337; OMIM: 602382; Uniprot ID:PLD1_HUMAN; ENSEMBL ID: ENSG00000075651; HGNC ID: 9067
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult68 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma0 / 1068830 
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal102 / 336030730
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone4 / 7165555
bone marrow2 / 4880140
brain26 / 110098923
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye9 / 21105442
heart5 / 8962655
intestine8 / 23447234
kidney15 / 21177770
larynx0 / 241450 
liver3 / 20774314
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth9 / 67052134
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate0 / 1893450 
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis11 / 33044233
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205203_at
Cell line Expression level Expression bar
721_B_lymphoblasts62.4
Adipocyte7.65
AdrenalCortex12.65
Adrenalgland6.45
Amygdala5.45
Appendix7.35
AtrioventricularNode6.45
BDCA4+_DentriticCells6.05
Bonemarrow7.05
BronchialEpithelialCells6.65
CD105+_Endothelial6.85
CD14+_Monocytes7.25
CD19+_BCells(neg._sel.)7
CD33+_Myeloid8.6
CD34+8.4
CD4+_Tcells6.8
CD56+_NKCells7.75
CD71+_EarlyErythroid6.4
CD8+_Tcells6.3
CardiacMyocytes9.2
Caudatenucleus6.15
Cerebellum5.55
CerebellumPeduncles10.1
CiliaryGanglion5.55
CingulateCortex7.1
Colorectaladenocarcinoma6.75
DorsalRootGanglion5.65
FetalThyroid8.05
Fetalbrain6.9
Fetalliver8.6
Fetallung5.55
GlobusPallidus5.2
Heart8.75
Hypothalamus7.5
Kidney5.7
Leukemia_chronicMyelogenousK-5627.1
Leukemia_promyelocytic-HL-606.05
Leukemialymphoblastic(MOLT-4)5.6
Liver9.95
Lung7.25
Lymphnode6.95
Lymphoma_burkitts(Daudi)8.9
Lymphoma_burkitts(Raji)9.6
MedullaOblongata6.2
OccipitalLobe7.1
OlfactoryBulb5.75
Ovary9.05
Pancreas5.8
PancreaticIslet7.4
ParietalLobe7.35
Pituitary7.9
Placenta6.75
Pons7.5
PrefrontalCortex8.2
Prostate8.4
Salivarygland8.45
SkeletalMuscle8.3
Skin9.65
SmoothMuscle7.7
Spinalcord9.9
SubthalamicNucleus6.25
SuperiorCervicalGanglion14.55
TemporalLobe6.35
Testis7.2
TestisGermCell6.35
TestisIntersitial5.95
TestisLeydigCell6.8
TestisSeminiferousTubule5.9
Thalamus8.7
Thymus4.75
Thyroid7.2
Tongue11.65
Tonsil8.6
Trachea5.6
TrigeminalGanglion13.05
Uterus5.35
UterusCorpus6.7
WholeBlood7.2
Wholebrain4.35
colon6.75
pineal_day7.94
pineal_night7.84
retina8.225
small_intestine6.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P155335
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.64 ± 0.57
Basal Forebrain8.04 ± 0.67
Basal Part of Pons7.61 ± 0.72
Cerebellar Cortex7.09 ± 0.44
Cerebellar Nuclei9.25 ± 0.6
Claustrum7.18 ± 0.68
Epithalamus7.32 ± 0.87
Frontal Lobe7.67 ± 0.96
Globus Pallidus9.72 ± 0.45
Hypothalamus7.43 ± 0.68
Insula7.13 ± 0.46
Limbic Lobe7.28 ± 0.88
Mesencephalon7.94 ± 0.94
Myelencephalon7.76 ± 0.88
Occipital Lobe7.94 ± 0.84
Parietal Lobe7.63 ± 0.86
Pontine Tegmentum8.08 ± 0.73
Striatum8.49 ± 0.78
Subthalamus8.5 ± 0.72
Temporal Lobe7.43 ± 0.74
Thalamus8.43 ± 0.48
White Matter11.06 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pld1CBCerebellum0
0
Pld1CTXCerebral cortex0
0
Pld1HIPHippocampal region0
0
Pld1HPFHippocampal formation0
0
Pld1HYHypothalamus0
0
Pld1LSXLateral septal complex0
0
Pld1MBMidbrain0
0
Pld1MYMedulla0
0
Pld1OLFOlfactory bulb0
0
Pld1PPons0
0
Pld1PALPallidum0
0
Pld1RHPRetrohippocampal region0
0
Pld1sAMYStriatum-like amygdalar nuclei0
0
Pld1STRStriatum0
0
Pld1STRdStriatum dorsal region0
0
Pld1STRvStriatum ventral region0
0
Pld1THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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