AutismKB 2.0

Annotation Detail for SERPINF2


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Basic Information Top
Gene Symbol:SERPINF2 ( A2AP,AAP,ALPHA-2-PI,API,PLI )
Gene Full Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Band: 17p13.3
Quick LinksEntrez ID:5345; OMIM: 613168; Uniprot ID:A2AP_HUMAN; ENSEMBL ID: ENSG00000167711; HGNC ID: 9075
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor9 / 9635993
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal79 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain4 / 11009893
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney15 / 21177770
larynx0 / 241450 
liver39 / 207743187
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen3 / 5395255
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205075_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.2
AdrenalCortex4.6
Adrenalgland3.6
Amygdala4.35
Appendix4.4
AtrioventricularNode3.75
BDCA4+_DentriticCells8.3
Bonemarrow4.15
BronchialEpithelialCells4.2
CD105+_Endothelial4.35
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)4.6
CD33+_Myeloid5.5
CD34+5.5
CD4+_Tcells4.7
CD56+_NKCells5.2
CD71+_EarlyErythroid4
CD8+_Tcells4.2
CardiacMyocytes5.35
Caudatenucleus3.85
Cerebellum3.45
CerebellumPeduncles4.8
CiliaryGanglion3.75
CingulateCortex4.4
Colorectaladenocarcinoma4.3
DorsalRootGanglion4.35
FetalThyroid4.2
Fetalbrain4.3
Fetalliver76
Fetallung11.35
GlobusPallidus3.25
Heart5.4
Hypothalamus4.7
Kidney70.85
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)3.45
Liver770.8
Lung4.85
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.6
Lymphoma_burkitts(Raji)5.95
MedullaOblongata3.9
OccipitalLobe3.85
OlfactoryBulb3.4
Ovary3
Pancreas3.45
PancreaticIslet4.6
ParietalLobe4.5
Pituitary5.05
Placenta4.45
Pons4.5
PrefrontalCortex5.35
Prostate5.05
Salivarygland4.05
SkeletalMuscle4.85
Skin3.5
SmoothMuscle4.85
Spinalcord4.55
SubthalamicNucleus3.9
SuperiorCervicalGanglion4.8
TemporalLobe3.9
Testis3.65
TestisGermCell3.6
TestisIntersitial3.5
TestisLeydigCell4.95
TestisSeminiferousTubule3.9
Thalamus4.6
Thymus3.4
Thyroid5.35
Tongue4.1
Tonsil4.1
Trachea3.6
TrigeminalGanglion4.25
Uterus3.45
UterusCorpus4.25
WholeBlood4.55
Wholebrain3.45
colon4.25
pineal_day5.72
pineal_night6.1
retina5.2
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P89270
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.35 ± 0.97
Basal Forebrain1.85 ± 0.42
Basal Part of Pons1.58 ± 0.34
Cerebellar Cortex1.71 ± 0.61
Cerebellar Nuclei2.1 ± 0.72
Claustrum2.5 ± 0.76
Epithalamus1.57 ± 0.61
Frontal Lobe1.8 ± 0.64
Globus Pallidus2.53 ± 0.75
Hypothalamus1.62 ± 0.63
Insula1.62 ± 0.47
Limbic Lobe1.85 ± 0.67
Mesencephalon2.04 ± 0.8
Myelencephalon1.9 ± 0.7
Occipital Lobe2.06 ± 0.78
Parietal Lobe1.93 ± 0.79
Pontine Tegmentum2 ± 0.71
Striatum2.17 ± 0.7
Subthalamus2.28 ± 0.26
Temporal Lobe1.78 ± 0.73
Thalamus2.07 ± 0.67
White Matter2.62 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Serpinf2CBCerebellum4.19
4.3
Serpinf2CTXCerebral cortex6.54
4.74
Serpinf2HIPHippocampal region10.97
9.96
Serpinf2HPFHippocampal formation8.46
7.09
Serpinf2HYHypothalamus2.03
1.36
Serpinf2LSXLateral septal complex4.2
3.01
Serpinf2MBMidbrain1.67
1.67
Serpinf2MYMedulla2.07
2.32
Serpinf2OLFOlfactory bulb6.98
5.19
Serpinf2PPons2.38
2.8
Serpinf2PALPallidum0.9
0.62
Serpinf2RHPRetrohippocampal region4.02
2.89
Serpinf2sAMYStriatum-like amygdalar nuclei0.54
0.3
Serpinf2STRStriatum1.41
0.97
Serpinf2STRdStriatum dorsal region0.79
0.57
Serpinf2STRvStriatum ventral region2.68
1.68
Serpinf2THThalamus3.98
2.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024751 19 253 271 DSFHLDEQFTVPVEMMQAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018