Annotation Detail for PLOD2
Basic Information Top
| Gene Symbol: | PLOD2 ( LH2,TLH ) |
|---|---|
| Gene Full Name: | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| Band: | 3q24 |
| Quick Links | Entrez ID:5352; OMIM: 601865; Uniprot ID:PLOD2_HUMAN; ENSEMBL ID: ENSG00000152952; HGNC ID: 9082 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.477866
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 8 / 70761 | 113 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 133 / 1939121 | 68 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 17 / 106883 | 159 | |
| head and neck tumor | 24 / 136302 | 176 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 1 / 103127 | 9 |  |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 169 / 3360307 | 50 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 3 / 123478 | 24 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 56 / 1100989 | 50 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 8 / 149255 | 53 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 5 / 211054 | 23 | |
| heart | 1 / 89626 | 11 | |
| intestine | 8 / 234472 | 34 | |
| kidney | 26 / 211777 | 122 | |
| larynx | 1 / 24145 | 41 | |
| liver | 16 / 207743 | 77 | |
| lung | 11 / 336974 | 32 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 7 / 67052 | 104 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 15 / 214812 | 69 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 21 / 280825 | 74 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 18 / 210574 | 85 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 4 / 96619 | 41 | |
| testis | 10 / 330442 | 30 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 17 / 47473 | 358 |  |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 9 / 51780 | 173 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202620_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 248.3 | |
| Adipocyte | 52.75 | |
| AdrenalCortex | 8.05 | |
| Adrenalgland | 6.1 | |
| Amygdala | 15.35 | |
| Appendix | 15.35 | |
| AtrioventricularNode | 7.1 | |
| BDCA4+_DentriticCells | 6.4 | |
| Bonemarrow | 6.95 | |
| BronchialEpithelialCells | 208.45 | |
| CD105+_Endothelial | 6.65 | |
| CD14+_Monocytes | 6.95 | |
| CD19+_BCells(neg._sel.) | 6.95 | |
| CD33+_Myeloid | 8.1 | |
| CD34+ | 14.8 | |
| CD4+_Tcells | 6.65 | |
| CD56+_NKCells | 7.25 | |
| CD71+_EarlyErythroid | 6.5 | |
| CD8+_Tcells | 5.85 | |
| CardiacMyocytes | 644.75 | |
| Caudatenucleus | 7.4 | |
| Cerebellum | 5.4 | |
| CerebellumPeduncles | 7.85 | |
| CiliaryGanglion | 7.2 | |
| CingulateCortex | 6.95 | |
| Colorectaladenocarcinoma | 6.5 | |
| DorsalRootGanglion | 6.3 | |
| FetalThyroid | 101.75 | |
| Fetalbrain | 6.55 | |
| Fetalliver | 86.05 | |
| Fetallung | 49.45 | |
| GlobusPallidus | 5.6 | |
| Heart | 10 | |
| Hypothalamus | 10.95 | |
| Kidney | 6.05 | |
| Leukemia_chronicMyelogenousK-562 | 24.25 | |
| Leukemia_promyelocytic-HL-60 | 5.85 | |
| Leukemialymphoblastic(MOLT-4) | 5 | |
| Liver | 9.6 | |
| Lung | 7.25 | |
| Lymphnode | 5.6 | |
| Lymphoma_burkitts(Daudi) | 8.75 | |
| Lymphoma_burkitts(Raji) | 9.9 | |
| MedullaOblongata | 6 | |
| OccipitalLobe | 5.9 | |
| OlfactoryBulb | 5.4 | |
| Ovary | 6.25 | |
| Pancreas | 5.6 | |
| PancreaticIslet | 200.7 | |
| ParietalLobe | 7.45 | |
| Pituitary | 8.55 | |
| Placenta | 7.1 | |
| Pons | 6.65 | |
| PrefrontalCortex | 12.4 | |
| Prostate | 7.75 | |
| Salivarygland | 5.65 | |
| SkeletalMuscle | 8.9 | |
| Skin | 6.4 | |
| SmoothMuscle | 2186.3 |  |
| Spinalcord | 23.55 | |
| SubthalamicNucleus | 6.3 | |
| SuperiorCervicalGanglion | 9.85 | |
| TemporalLobe | 6.5 | |
| Testis | 5.7 | |
| TestisGermCell | 10.7 | |
| TestisIntersitial | 5.6 | |
| TestisLeydigCell | 6.95 | |
| TestisSeminiferousTubule | 5.75 | |
| Thalamus | 7 | |
| Thymus | 5.05 | |
| Thyroid | 490.55 | |
| Tongue | 7.25 | |
| Tonsil | 6.55 | |
| Trachea | 13.45 | |
| TrigeminalGanglion | 9.25 | |
| Uterus | 53.1 | |
| UterusCorpus | 6.9 | |
| WholeBlood | 7.2 | |
| Wholebrain | 5.45 | |
| colon | 124.5 | |
| pineal_day | 37.5 | |
| pineal_night | 23.92 | |
| retina | 12.5 | |
| small_intestine | 86.05 | |
- Probe name: CUST_9445_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.99 ± 0.53 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.14 ± 0.31 | |
| Basal Part of Pons | 4.19 ± 0.4 | |
| Cerebellar Cortex | 4.38 ± 0.33 | |
| Cerebellar Nuclei | 4.21 ± 0.63 | |
| Claustrum | 4.49 ± 0.75 | |
| Epithalamus | 6.01 ± 0.68 | |
| Frontal Lobe | 4.76 ± 0.5 | |
| Globus Pallidus | 6.13 ± 0.31 | |
| Hypothalamus | 5.32 ± 0.43 | |
| Insula | 4.8 ± 0.24 | |
| Limbic Lobe | 4.58 ± 0.52 | |
| Mesencephalon | 5.28 ± 0.45 | |
| Myelencephalon | 4.95 ± 0.68 | |
| Occipital Lobe | 5.31 ± 0.57 | |
| Parietal Lobe | 5.04 ± 0.44 | |
| Pontine Tegmentum | 4.98 ± 0.47 | |
| Striatum | 5.72 ± 0.35 | |
| Subthalamus | 5.3 ± 0.05 | |
| Temporal Lobe | 4.88 ± 0.47 | |
| Thalamus | 5.03 ± 0.59 | |
| White Matter | 4.97 ± 0.34 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Plod2 | CB | Cerebellum | 10.18 | |
| 12.71 | | |||
| Plod2 | CTX | Cerebral cortex | 28.55 | |
| 20.11 | | |||
| Plod2 | HIP | Hippocampal region | 21.01 | |
| 20.09 | | |||
| Plod2 | HPF | Hippocampal formation | 21.17 | |
| 18.25 | | |||
| Plod2 | HY | Hypothalamus | 10.53 | |
| 7.92 | | |||
| Plod2 | LSX | Lateral septal complex | 12.31 | |
| 10.67 | | |||
| Plod2 | MB | Midbrain | 7.79 | |
| 9.08 | | |||
| Plod2 | MY | Medulla | 5.55 | |
| 6.98 | | |||
| Plod2 | OLF | Olfactory bulb | 24.95 | |
| 18.24 | | |||
| Plod2 | P | Pons | 10.75 | |
| 12.76 | | |||
| Plod2 | PAL | Pallidum | 7.04 | |
| 6.24 | | |||
| Plod2 | RHP | Retrohippocampal region | 21.67 | |
| 15.75 | | |||
| Plod2 | sAMY | Striatum-like amygdalar nuclei | 9.67 | |
| 6.71 | | |||
| Plod2 | STR | Striatum | 7.79 | |
| 6.09 | | |||
| Plod2 | STRd | Striatum dorsal region | 5.76 | |
| 4.59 | | |||
| Plod2 | STRv | Striatum ventral region | 11.17 | |
| 7.99 | | |||
| Plod2 | TH | Thalamus | 8.61 | |
| 7.51 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00009165 | 14 | 596 | 609 | ACDELVEEMEHYGK | Peptide Atlas |
| PLOD2_HUMAN_358 | 14 | 358 | 371 | IVGPEENLSQAEAR | PRIDE |
| PLOD2_HUMAN_499 | 11 | 499 | 509 | EMGVFMYISNR | PRIDE |
| PLOD2_HUMAN_704 | 10 | 704 | 713 | KGWSFMHPGR | PRIDE |