AutismKB 2.0

Annotation Detail for PLSCR1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLSCR1 ( MMTRA1B )
Gene Full Name: phospholipid scramblase 1
Band: 3q24
Quick LinksEntrez ID:5359; OMIM: 604170; Uniprot ID:PLS1_HUMAN; ENSEMBL ID: ENSG00000188313; HGNC ID: 9092
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus16 / 56401228
neonate3 / 3109796
infant0 / 236200 
juvenile3 / 5555653
adult322 / 1939121166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor22 / 94178233
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor11 / 11424696
esophageal tumor4 / 17290231
gastrointestinal tumor43 / 119369360
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia10 / 95842104
liver tumor7 / 9635972
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal224 / 336030766
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor26 / 125191207
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites8 / 40015199
bladder11 / 29757369
blood18 / 123478145
bone4 / 7165555
bone marrow8 / 48801163
brain22 / 110098919
cervix3 / 4817162
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus4 / 20209197
eye1 / 2110544
heart3 / 8962633
intestine18 / 23447276
kidney11 / 21177751
larynx5 / 24145207
liver12 / 20774357
lung21 / 33697462
lymph0 / 442700 
lymph node5 / 9161054
mammary gland86 / 153271561
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary5 / 10205148
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta25 / 28082589
prostate2 / 18934510
salivary gland2 / 2015599
skin16 / 21057475
spleen0 / 539520 
stomach36 / 96619372
testis6 / 33044218
thymus1 / 8113112
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord1 / 1368073
uterus32 / 232878137
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202446_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts157.7
Adipocyte13.25
AdrenalCortex10.4
Adrenalgland8.75
Amygdala13.45
Appendix23.35
AtrioventricularNode17.7
BDCA4+_DentriticCells224.75
Bonemarrow90.3
BronchialEpithelialCells26.25
CD105+_Endothelial176.8
CD14+_Monocytes457.1
CD19+_BCells(neg._sel.)61.15
CD33+_Myeloid500.55
CD34+154.15
CD4+_Tcells38
CD56+_NKCells170.7
CD71+_EarlyErythroid37.75
CD8+_Tcells45.4
CardiacMyocytes96.55
Caudatenucleus8.45
Cerebellum7.8
CerebellumPeduncles7.5
CiliaryGanglion16.45
CingulateCortex8.75
Colorectaladenocarcinoma42.6
DorsalRootGanglion15
FetalThyroid16.95
Fetalbrain14.7
Fetalliver29.75
Fetallung134.2
GlobusPallidus5.3
Heart19.05
Hypothalamus17.75
Kidney11.5
Leukemia_chronicMyelogenousK-56249.35
Leukemia_promyelocytic-HL-607.55
Leukemialymphoblastic(MOLT-4)19.3
Liver9.5
Lung61
Lymphnode74
Lymphoma_burkitts(Daudi)34.1
Lymphoma_burkitts(Raji)22.55
MedullaOblongata6.95
OccipitalLobe9.55
OlfactoryBulb25.1
Ovary33.75
Pancreas91.1
PancreaticIslet176.55
ParietalLobe8.8
Pituitary15.7
Placenta71.2
Pons8.8
PrefrontalCortex22.8
Prostate35.45
Salivarygland136
SkeletalMuscle14.8
Skin14.9
SmoothMuscle141.95
Spinalcord13.5
SubthalamicNucleus7.95
SuperiorCervicalGanglion14
TemporalLobe9.3
Testis14.2
TestisGermCell31.95
TestisIntersitial24.45
TestisLeydigCell16.35
TestisSeminiferousTubule12.65
Thalamus6.95
Thymus49.55
Thyroid69.75
Tongue18.85
Tonsil109.5
Trachea85.95
TrigeminalGanglion17.2
Uterus65.85
UterusCorpus14.6
WholeBlood349.4
Wholebrain6.1
colon263.45
pineal_day17.26
pineal_night17.58
retina68.375
small_intestine132.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9060_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.12 ± 0.58
Basal Forebrain4.69 ± 0.36
Basal Part of Pons4.32 ± 0.6
Cerebellar Cortex4.01 ± 0.42
Cerebellar Nuclei5.27 ± 0.3
Claustrum3.73 ± 0.78
Epithalamus4.94 ± 0.59
Frontal Lobe4.36 ± 0.54
Globus Pallidus5.7 ± 0.36
Hypothalamus4.87 ± 0.54
Insula4.45 ± 0.35
Limbic Lobe4.07 ± 0.62
Mesencephalon4.58 ± 0.6
Myelencephalon4.63 ± 0.66
Occipital Lobe4.79 ± 0.56
Parietal Lobe4.49 ± 0.58
Pontine Tegmentum4.61 ± 0.59
Striatum5.28 ± 0.35
Subthalamus4.53 ± 0.46
Temporal Lobe4.49 ± 0.52
Thalamus4.58 ± 0.6
White Matter4.33 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plscr1CBCerebellum0.13
0.4
Plscr1CTXCerebral cortex0.25
0.5
Plscr1HIPHippocampal region0.34
0.59
Plscr1HPFHippocampal formation0.32
0.65
Plscr1HYHypothalamus4.1
5.54
Plscr1LSXLateral septal complex0.05
0
Plscr1MBMidbrain0.19
0.88
Plscr1MYMedulla0.13
0.53
Plscr1OLFOlfactory bulb1.39
2.98
Plscr1PPons0.61
2.21
Plscr1PALPallidum0.46
0.59
Plscr1RHPRetrohippocampal region0.17
0.59
Plscr1sAMYStriatum-like amygdalar nuclei3.88
6.82
Plscr1STRStriatum0.75
1.14
Plscr1STRdStriatum dorsal region0.26
0.29
Plscr1STRvStriatum ventral region1.02
1.31
Plscr1THThalamus0.09
0.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved