AutismKB 2.0

Annotation Detail for PLXNB1


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Basic Information Top
Gene Symbol:PLXNB1 ( KIAA0407,MGC149167,PLEXIN-B1,PLXN5,SEP )
Gene Full Name: plexin B1
Band: 3p21.31
Quick LinksEntrez ID:5364; OMIM: 601053; Uniprot ID:PLXB1_HUMAN; ENSEMBL ID: ENSG00000164050; HGNC ID: 9103
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult168 / 193912186
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor16 / 114246140
esophageal tumor3 / 17290173
gastrointestinal tumor7 / 11936958
germ cell tumor5 / 26384518
glioma12 / 106883112
head and neck tumor19 / 136302139
kidney tumor10 / 68959145
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal224 / 336030766
ovarian tumor7 / 7668291
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain114 / 1100989103
cervix1 / 4817120
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus3 / 20209148
eye10 / 21105447
heart1 / 8962611
intestine22 / 23447293
kidney17 / 21177780
larynx6 / 24145248
liver6 / 20774328
lung18 / 33697453
lymph0 / 442700 
lymph node1 / 9161010
mammary gland12 / 15327178
mouth4 / 6705259
muscle7 / 10771564
nerve2 / 15768126
ovary10 / 10205197
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta10 / 28082535
prostate30 / 189345158
salivary gland0 / 201550 
skin12 / 21057456
spleen0 / 539520 
stomach5 / 9661951
testis8 / 33044224
thymus3 / 8113136
thyroid8 / 47473168
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus18 / 23287877
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215807_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.95
Adipocyte7
AdrenalCortex4.2
Adrenalgland3.45
Amygdala29.5
Appendix4
AtrioventricularNode2.9
BDCA4+_DentriticCells4.3
Bonemarrow3.75
BronchialEpithelialCells4.1
CD105+_Endothelial3.5
CD14+_Monocytes3.3
CD19+_BCells(neg._sel.)4.25
CD33+_Myeloid4.75
CD34+4.95
CD4+_Tcells4.25
CD56+_NKCells4.6
CD71+_EarlyErythroid3.6
CD8+_Tcells3.8
CardiacMyocytes7.8
Caudatenucleus26.45
Cerebellum14.6
CerebellumPeduncles18.7
CiliaryGanglion2.75
CingulateCortex7.25
Colorectaladenocarcinoma34.75
DorsalRootGanglion3
FetalThyroid10
Fetalbrain7.85
Fetalliver10.15
Fetallung6.85
GlobusPallidus3.45
Heart10.7
Hypothalamus36.4
Kidney15.2
Leukemia_chronicMyelogenousK-5623.75
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.35
Liver10.55
Lung7.6
Lymphnode3.35
Lymphoma_burkitts(Daudi)5.2
Lymphoma_burkitts(Raji)5.4
MedullaOblongata12.35
OccipitalLobe21.75
OlfactoryBulb4.55
Ovary2.75
Pancreas3.85
PancreaticIslet4.25
ParietalLobe15.2
Pituitary4.8
Placenta7.95
Pons7.3
PrefrontalCortex51.5
Prostate21.55
Salivarygland3
SkeletalMuscle4.4
Skin3
SmoothMuscle4.6
Spinalcord37.7
SubthalamicNucleus5.2
SuperiorCervicalGanglion4.45
TemporalLobe3.75
Testis3.5
TestisGermCell3.3
TestisIntersitial3.25
TestisLeydigCell3.9
TestisSeminiferousTubule3.4
Thalamus5.85
Thymus3.3
Thyroid26.75
Tongue3.9
Tonsil3.8
Trachea9.5
TrigeminalGanglion4
Uterus3.85
UterusCorpus3.85
WholeBlood4.3
Wholebrain19.45
colon5.2
pineal_day5.94
pineal_night5.02
retina35.925
small_intestine4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P57961
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.25 ± 0.44
Basal Forebrain5.7 ± 0.25
Basal Part of Pons5.08 ± 0.63
Cerebellar Cortex5.16 ± 0.49
Cerebellar Nuclei5.2 ± 0.63
Claustrum4.6 ± 0.87
Epithalamus6.27 ± 0.53
Frontal Lobe5.3 ± 0.69
Globus Pallidus6.54 ± 0.3
Hypothalamus5.43 ± 0.32
Insula5.1 ± 0.44
Limbic Lobe5.06 ± 0.66
Mesencephalon5.48 ± 0.64
Myelencephalon5.49 ± 0.59
Occipital Lobe5.56 ± 0.54
Parietal Lobe5.28 ± 0.59
Pontine Tegmentum5.51 ± 0.55
Striatum5.93 ± 0.4
Subthalamus5.16 ± 0.67
Temporal Lobe5.35 ± 0.43
Thalamus5.78 ± 0.49
White Matter7.41 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Plxnb1CBCerebellum0.12
0.18
Plxnb1CTXCerebral cortex0.16
0.17
Plxnb1HIPHippocampal region0.17
0.13
Plxnb1HPFHippocampal formation0.17
0.14
Plxnb1HYHypothalamus0.08
0.09
Plxnb1LSXLateral septal complex0.07
0.04
Plxnb1MBMidbrain0.13
0.14
Plxnb1MYMedulla0.18
0.11
Plxnb1OLFOlfactory bulb0.16
0.27
Plxnb1PPons0.55
0.65
Plxnb1PALPallidum0.06
0.03
Plxnb1RHPRetrohippocampal region0.16
0.14
Plxnb1sAMYStriatum-like amygdalar nuclei0.21
0.25
Plxnb1STRStriatum0.11
0.09
Plxnb1STRdStriatum dorsal region0.1
0.08
Plxnb1STRvStriatum ventral region0.08
0.05
Plxnb1THThalamus2.47
1.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011997 20 1197 1216 VVVGDQPCHLLPEQQSEQLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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