AutismKB 2.0

Annotation Detail for FXYD5


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Basic Information Top
Gene Symbol:FXYD5 ( DYSAD,IWU1,KCT1,OIT2,PRO6241,RIC )
Gene Full Name: FXYD domain containing ion transport regulator 5
Band: 19q13.12
Quick LinksEntrez ID:53827; OMIM: 606669; Uniprot ID:FXYD5_HUMAN; ENSEMBL ID: ENSG00000089327; HGNC ID: 4029
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus19 / 56401233
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult130 / 193912167
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma3 / 17475171
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor18 / 119369150
germ cell tumor16 / 26384560
glioma8 / 10688374
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia11 / 95842114
liver tumor1 / 9635910
lung tumor13 / 103127126
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal143 / 336030742
ovarian tumor0 / 766820 
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor25 / 124949200
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder3 / 29757100
blood15 / 123478121
bone3 / 7165541
bone marrow5 / 48801102
brain18 / 110098916
cervix0 / 481710 
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye11 / 21105452
heart4 / 8962644
intestine21 / 23447289
kidney4 / 21177718
larynx0 / 241450 
liver4 / 20774319
lung27 / 33697480
lymph1 / 4427022
lymph node14 / 91610152
mammary gland14 / 15327191
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas25 / 214812116
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta11 / 28082539
prostate7 / 18934536
salivary gland4 / 20155198
skin28 / 210574132
spleen3 / 5395255
stomach16 / 96619165
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil3 / 16999176
trachea1 / 5241319
umbilical cord2 / 13680146
uterus11 / 23287847
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218084_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts171.35
Adipocyte19.05
AdrenalCortex6.9
Adrenalgland5.4
Amygdala5.05
Appendix20.85
AtrioventricularNode5.35
BDCA4+_DentriticCells487.65
Bonemarrow125.85
BronchialEpithelialCells87.7
CD105+_Endothelial8.7
CD14+_Monocytes690.85
CD19+_BCells(neg._sel.)1306.35
CD33+_Myeloid482.3
CD34+350.05
CD4+_Tcells649.6
CD56+_NKCells557.45
CD71+_EarlyErythroid4.75
CD8+_Tcells392.6
CardiacMyocytes224.75
Caudatenucleus4.4
Cerebellum4.4
CerebellumPeduncles6.35
CiliaryGanglion9.9
CingulateCortex4.95
Colorectaladenocarcinoma47.3
DorsalRootGanglion7.95
FetalThyroid7.45
Fetalbrain6.05
Fetalliver4.7
Fetallung22.5
GlobusPallidus4.2
Heart155.05
Hypothalamus6.7
Kidney4.35
Leukemia_chronicMyelogenousK-562129.4
Leukemia_promyelocytic-HL-6013.25
Leukemialymphoblastic(MOLT-4)25.95
Liver8.6
Lung211.9
Lymphnode219.1
Lymphoma_burkitts(Daudi)164
Lymphoma_burkitts(Raji)125.45
MedullaOblongata4.9
OccipitalLobe4.8
OlfactoryBulb21.45
Ovary13.35
Pancreas32.35
PancreaticIslet58.35
ParietalLobe5.25
Pituitary11.8
Placenta93.35
Pons7.65
PrefrontalCortex7.2
Prostate28.55
Salivarygland10.65
SkeletalMuscle6.5
Skin8.15
SmoothMuscle219.15
Spinalcord8.3
SubthalamicNucleus4.5
SuperiorCervicalGanglion14.35
TemporalLobe5.2
Testis4.65
TestisGermCell5.85
TestisIntersitial5.55
TestisLeydigCell5.35
TestisSeminiferousTubule4.85
Thalamus6.1
Thymus90.55
Thyroid7.6
Tongue6
Tonsil72.7
Trachea8.8
TrigeminalGanglion12.1
Uterus33.6
UterusCorpus59.85
WholeBlood623.65
Wholebrain5.3
colon4.95
pineal_day6.22
pineal_night5.82
retina10.55
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P194081
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.43 ± 0.54
Basal Forebrain4.31 ± 0.27
Basal Part of Pons4.57 ± 0.56
Cerebellar Cortex4 ± 0.45
Cerebellar Nuclei5.19 ± 0.44
Claustrum4.58 ± 0.96
Epithalamus4.95 ± 0.54
Frontal Lobe4.36 ± 0.57
Globus Pallidus5.63 ± 0.25
Hypothalamus4.59 ± 1.02
Insula4.43 ± 0.61
Limbic Lobe4.35 ± 0.64
Mesencephalon4.49 ± 0.58
Myelencephalon4.48 ± 0.66
Occipital Lobe4.56 ± 0.52
Parietal Lobe4.37 ± 0.69
Pontine Tegmentum4.53 ± 0.68
Striatum5.08 ± 0.48
Subthalamus4.53 ± 0.43
Temporal Lobe4.45 ± 0.6
Thalamus4.49 ± 0.57
White Matter5.19 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fxyd5CBCerebellum5.29
7.81
Fxyd5CTXCerebral cortex32.9
21.35
Fxyd5HIPHippocampal region11.3
11.6
Fxyd5HPFHippocampal formation21.27
18.28
Fxyd5HYHypothalamus5.44
5.22
Fxyd5LSXLateral septal complex4.42
3.31
Fxyd5MBMidbrain5.31
6.62
Fxyd5MYMedulla8.93
8.5
Fxyd5OLFOlfactory bulb25.27
18.99
Fxyd5PPons6.03
7.12
Fxyd5PALPallidum7.57
6.71
Fxyd5RHPRetrohippocampal region37.72
27.36
Fxyd5sAMYStriatum-like amygdalar nuclei11.45
8.22
Fxyd5STRStriatum12.52
8.69
Fxyd5STRdStriatum dorsal region12.97
8.9
Fxyd5STRvStriatum ventral region15.41
10.18
Fxyd5THThalamus9.41
7.05
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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