AutismKB 2.0

Annotation Detail for FGFRL1


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Basic Information Top
Gene Symbol:FGFRL1 ( FGFR5,FHFR )
Gene Full Name: fibroblast growth factor receptor-like 1
Band: 4p16.3
Quick LinksEntrez ID:53834; OMIM: 605830; Uniprot ID:FGRL1_HUMAN; ENSEMBL ID: ENSG00000127418; HGNC ID: 3693
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor12 / 119369100
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor11 / 103127106
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal48 / 336030714
ovarian tumor11 / 76682143
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer21 / 102680204
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites4 / 4001599
bladder0 / 297570 
blood0 / 1234780 
bone6 / 7165583
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine19 / 23447281
kidney10 / 21177747
larynx0 / 241450 
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth2 / 6705229
muscle7 / 10771564
nerve0 / 157680 
ovary12 / 102051117
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate24 / 189345126
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach2 / 9661920
testis4 / 33044212
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P92349
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.45 ± 0.63
Basal Forebrain4.55 ± 0.53
Basal Part of Pons3.99 ± 0.89
Cerebellar Cortex3.97 ± 0.47
Cerebellar Nuclei3.98 ± 0.47
Claustrum3.56 ± 1.09
Epithalamus4.3 ± 0.62
Frontal Lobe4.37 ± 0.72
Globus Pallidus4.06 ± 0.57
Hypothalamus4.38 ± 0.58
Insula4.41 ± 0.58
Limbic Lobe4.21 ± 0.72
Mesencephalon4.34 ± 0.77
Myelencephalon4.41 ± 0.66
Occipital Lobe4.95 ± 0.59
Parietal Lobe4.51 ± 0.56
Pontine Tegmentum4.49 ± 0.64
Striatum5.11 ± 0.54
Subthalamus4.34 ± 0.33
Temporal Lobe4.36 ± 0.61
Thalamus4.29 ± 0.61
White Matter3.63 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fgfrl1CBCerebellum2.98
2.98
Fgfrl1CTXCerebral cortex0.83
0.72
Fgfrl1HIPHippocampal region0.42
0.46
Fgfrl1HPFHippocampal formation0.43
0.51
Fgfrl1HYHypothalamus0.36
0.35
Fgfrl1LSXLateral septal complex0.23
0.17
Fgfrl1MBMidbrain0.84
0.65
Fgfrl1MYMedulla1.44
0.99
Fgfrl1OLFOlfactory bulb1.33
1.86
Fgfrl1PPons0.72
0.43
Fgfrl1PALPallidum0.23
0.11
Fgfrl1RHPRetrohippocampal region0.45
0.64
Fgfrl1sAMYStriatum-like amygdalar nuclei0.34
0.23
Fgfrl1STRStriatum0.35
0.32
Fgfrl1STRdStriatum dorsal region0.4
0.43
Fgfrl1STRvStriatum ventral region0.18
0.09
Fgfrl1THThalamus0.5
0.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00043050 9 496 504 VHQHIHYQC Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018