AutismKB 2.0

Annotation Detail for A4GALT


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:A4GALT ( A14GALT,A4GALT1,Gb3S,P(k),P1,PK )
Gene Full Name: alpha 1,4-galactosyltransferase
Band: 22q13.2
Quick LinksEntrez ID:53947; OMIM: 607922; Uniprot ID:A4GAT_HUMAN; ENSEMBL ID: ENSG00000128274; HGNC ID: 18149
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma14 / 71755195
non-neoplasia4 / 9725041
normal90 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder3 / 29757100
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain20 / 110098918
cervix2 / 4817141
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye2 / 2110549
heart4 / 8962644
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph3 / 4427067
lymph node4 / 9161043
mammary gland5 / 15327132
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate12 / 18934563
salivary gland2 / 2015599
skin7 / 21057433
spleen11 / 53952203
stomach2 / 9661920
testis2 / 3304426
thymus4 / 8113149
thyroid0 / 474730 
tonsil2 / 16999117
trachea3 / 5241357
umbilical cord0 / 136800 
uterus17 / 23287872
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219488_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.5
Adipocyte11.1
AdrenalCortex10
Adrenalgland7.9
Amygdala9.75
Appendix7.75
AtrioventricularNode7.4
BDCA4+_DentriticCells10.15
Bonemarrow9.35
BronchialEpithelialCells13.1
CD105+_Endothelial9.4
CD14+_Monocytes9.95
CD19+_BCells(neg._sel.)9.85
CD33+_Myeloid11.8
CD34+11.8
CD4+_Tcells13.8
CD56+_NKCells11.1
CD71+_EarlyErythroid19.4
CD8+_Tcells8.95
CardiacMyocytes12.5
Caudatenucleus8.45
Cerebellum7.6
CerebellumPeduncles10.7
CiliaryGanglion6.7
CingulateCortex12.4
Colorectaladenocarcinoma9.45
DorsalRootGanglion8.45
FetalThyroid9.3
Fetalbrain9.35
Fetalliver8.15
Fetallung7.7
GlobusPallidus8.1
Heart16.55
Hypothalamus10.3
Kidney7.7
Leukemia_chronicMyelogenousK-5628.5
Leukemia_promyelocytic-HL-6011.85
Leukemialymphoblastic(MOLT-4)7.5
Liver15.35
Lung10.3
Lymphnode8.15
Lymphoma_burkitts(Daudi)12
Lymphoma_burkitts(Raji)13.4
MedullaOblongata8.4
OccipitalLobe8.35
OlfactoryBulb7.45
Ovary6.2
Pancreas7.5
PancreaticIslet12.3
ParietalLobe9.85
Pituitary10.95
Placenta9.9
Pons8.9
PrefrontalCortex11.5
Prostate10.85
Salivarygland7.5
SkeletalMuscle11.15
Skin7.3
SmoothMuscle15.25
Spinalcord10
SubthalamicNucleus8.6
SuperiorCervicalGanglion7.7
TemporalLobe9.05
Testis7.05
TestisGermCell7.75
TestisIntersitial7.8
TestisLeydigCell9.1
TestisSeminiferousTubule8.05
Thalamus9.6
Thymus7.3
Thyroid11.9
Tongue9.3
Tonsil9.6
Trachea7.85
TrigeminalGanglion9.9
Uterus7.75
UterusCorpus20.25
WholeBlood10.15
Wholebrain7.9
colon9.5
pineal_day10.86
pineal_night10.54
retina11.375
small_intestine9.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11247_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.17 ± 0.94
Basal Forebrain1.59 ± 0.23
Basal Part of Pons1.61 ± 0.45
Cerebellar Cortex1.89 ± 0.66
Cerebellar Nuclei2.08 ± 0.68
Claustrum2.22 ± 0.55
Epithalamus1.58 ± 0.9
Frontal Lobe1.87 ± 0.64
Globus Pallidus1.66 ± 0.92
Hypothalamus1.72 ± 0.66
Insula1.74 ± 0.47
Limbic Lobe1.96 ± 0.7
Mesencephalon2.01 ± 0.71
Myelencephalon1.93 ± 0.7
Occipital Lobe2.12 ± 0.73
Parietal Lobe2.03 ± 0.78
Pontine Tegmentum1.97 ± 0.72
Striatum1.6 ± 0.78
Subthalamus2.22 ± 0.36
Temporal Lobe1.95 ± 0.74
Thalamus1.83 ± 0.71
White Matter1.56 ± 0.66
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
A4galtCBCerebellum5.49
8.37
A4galtCTXCerebral cortex1.31
1.21
A4galtHIPHippocampal region0.49
0.59
A4galtHPFHippocampal formation1.17
1.52
A4galtHYHypothalamus1.95
1.73
A4galtLSXLateral septal complex3.46
4.48
A4galtMBMidbrain0.93
1.52
A4galtMYMedulla12.34
17.8
A4galtOLFOlfactory bulb1.36
1.17
A4galtPPons4.84
6.32
A4galtPALPallidum0.77
0.72
A4galtRHPRetrohippocampal region1.74
2.11
A4galtsAMYStriatum-like amygdalar nuclei3.77
3.16
A4galtSTRStriatum1.29
1.17
A4galtSTRdStriatum dorsal region0.67
0.62
A4galtSTRvStriatum ventral region0.82
0.55
A4galtTHThalamus1.05
1.18
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved