AutismKB 2.0

Annotation Detail for C21orf58


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Basic Information Top
Gene Symbol:C21orf58 ( - )
Gene Full Name: chromosome 21 open reading frame 58
Band: 21q22.3
Quick LinksEntrez ID:54058; OMIM: NA; Uniprot ID:CU058_HUMAN; ENSEMBL ID: ENSG00000160298; HGNC ID: 1300
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow3 / 4880161
brain19 / 110098917
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye1 / 2110544
heart1 / 8962611
intestine7 / 23447229
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph1 / 4427022
lymph node1 / 9161010
mammary gland4 / 15327126
mouth3 / 6705244
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus14 / 81131172
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8116_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.35 ± 1.11
Basal Forebrain1.74 ± 0.32
Basal Part of Pons1.59 ± 0.52
Cerebellar Cortex2.24 ± 0.5
Cerebellar Nuclei2.21 ± 0.64
Claustrum2.51 ± 0.72
Epithalamus1.76 ± 0.64
Frontal Lobe1.78 ± 0.7
Globus Pallidus1.79 ± 0.71
Hypothalamus1.72 ± 0.73
Insula1.95 ± 0.75
Limbic Lobe1.81 ± 0.65
Mesencephalon2.08 ± 0.69
Myelencephalon1.93 ± 0.68
Occipital Lobe2.17 ± 0.71
Parietal Lobe1.91 ± 0.7
Pontine Tegmentum1.93 ± 0.72
Striatum2.02 ± 0.73
Subthalamus2.08 ± 0.82
Temporal Lobe1.82 ± 0.77
Thalamus1.9 ± 0.62
White Matter2.13 ± 0.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2610028H24RikCBCerebellum100
100
2610028H24RikCTXCerebral cortex100
100
2610028H24RikHIPHippocampal region100
100
2610028H24RikHPFHippocampal formation100
100
2610028H24RikHYHypothalamus100
100
2610028H24RikLSXLateral septal complex100
100
2610028H24RikMBMidbrain100
100
2610028H24RikMYMedulla100
100
2610028H24RikOLFOlfactory bulb100
100
2610028H24RikPPons100
100
2610028H24RikPALPallidum100
100
2610028H24RikRHPRetrohippocampal region100
100
2610028H24RiksAMYStriatum-like amygdalar nuclei100
100
2610028H24RikSTRStriatum100
100
2610028H24RikSTRdStriatum dorsal region100
100
2610028H24RikSTRvStriatum ventral region100
100
2610028H24RikTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018