AutismKB 2.0

Annotation Detail for PION


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PION ( DKFZp667B242,MGC126548 )
Gene Full Name: pigeon homolog (Drosophila)
Band: 7q11.23
Quick LinksEntrez ID:54103; OMIM: 613552; Uniprot ID:GSAP_HUMAN; ENSEMBL ID: ENSG00000186088; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal72 / 336030721
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine12 / 23447251
kidney7 / 21177733
larynx0 / 241450 
liver6 / 20774328
lung23 / 33697468
lymph0 / 442700 
lymph node13 / 91610141
mammary gland2 / 15327113
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary1 / 1020519
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach3 / 9661931
testis4 / 33044212
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222150_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.5
Adipocyte4.7
AdrenalCortex5.4
Adrenalgland4.2
Amygdala5.85
Appendix7.2
AtrioventricularNode5.25
BDCA4+_DentriticCells81.95
Bonemarrow4.95
BronchialEpithelialCells4.65
CD105+_Endothelial16
CD14+_Monocytes120.5
CD19+_BCells(neg._sel.)355.65
CD33+_Myeloid306.4
CD34+61.15
CD4+_Tcells144.25
CD56+_NKCells570.4
CD71+_EarlyErythroid4.55
CD8+_Tcells160.9
CardiacMyocytes6.65
Caudatenucleus4.4
Cerebellum3.95
CerebellumPeduncles5.7
CiliaryGanglion3.6
CingulateCortex5.35
Colorectaladenocarcinoma4.85
DorsalRootGanglion6.45
FetalThyroid5.95
Fetalbrain4.75
Fetalliver4.4
Fetallung9.15
GlobusPallidus4
Heart6.4
Hypothalamus5.7
Kidney4.05
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.8
Liver6.7
Lung5.3
Lymphnode86.9
Lymphoma_burkitts(Daudi)6.3
Lymphoma_burkitts(Raji)7
MedullaOblongata4.3
OccipitalLobe4.3
OlfactoryBulb4
Ovary3.35
Pancreas4.05
PancreaticIslet5.35
ParietalLobe5.3
Pituitary28.8
Placenta4.85
Pons4.75
PrefrontalCortex7.65
Prostate5.65
Salivarygland9.7
SkeletalMuscle5.9
Skin6.05
SmoothMuscle5.45
Spinalcord5.5
SubthalamicNucleus5.65
SuperiorCervicalGanglion11.6
TemporalLobe4.7
Testis4.1
TestisGermCell3.95
TestisIntersitial4.15
TestisLeydigCell5
TestisSeminiferousTubule4.1
Thalamus5.15
Thymus3.65
Thyroid24.25
Tongue5
Tonsil20.55
Trachea4
TrigeminalGanglion7.1
Uterus3.9
UterusCorpus4.4
WholeBlood26.95
Wholebrain4
colon4.8
pineal_day158.22
pineal_night112.22
retina5.975
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P416894
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.73 ± 0.58
Basal Forebrain5.26 ± 0.33
Basal Part of Pons4.94 ± 0.51
Cerebellar Cortex5.11 ± 0.34
Cerebellar Nuclei5.75 ± 0.35
Claustrum4.79 ± 0.51
Epithalamus5.67 ± 0.37
Frontal Lobe5.48 ± 0.37
Globus Pallidus5.9 ± 0.35
Hypothalamus5.98 ± 0.31
Insula5.58 ± 0.26
Limbic Lobe5.6 ± 0.42
Mesencephalon5.61 ± 0.37
Myelencephalon5.53 ± 0.41
Occipital Lobe6 ± 0.4
Parietal Lobe5.71 ± 0.37
Pontine Tegmentum5.63 ± 0.45
Striatum5.22 ± 0.51
Subthalamus5.77 ± 0.41
Temporal Lobe5.6 ± 0.36
Thalamus5.34 ± 0.39
White Matter5 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
A530088I07RikCBCerebellum21.21
35.88
A530088I07RikCTXCerebral cortex2.28
1.95
A530088I07RikHIPHippocampal region3.45
3.13
A530088I07RikHPFHippocampal formation4.32
3.56
A530088I07RikHYHypothalamus0.53
0.44
A530088I07RikLSXLateral septal complex1.56
1.71
A530088I07RikMBMidbrain1.76
2.63
A530088I07RikMYMedulla3.85
4.03
A530088I07RikOLFOlfactory bulb15.42
11.79
A530088I07RikPPons1.7
1.9
A530088I07RikPALPallidum0.48
0.42
A530088I07RikRHPRetrohippocampal region6.23
4.37
A530088I07RiksAMYStriatum-like amygdalar nuclei1.9
1.8
A530088I07RikSTRStriatum1.22
1.25
A530088I07RikSTRdStriatum dorsal region1.19
1.33
A530088I07RikSTRvStriatum ventral region0.61
0.37
A530088I07RikTHThalamus3.19
3.93
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved