AutismKB 2.0

Annotation Detail for C8orf58


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Basic Information Top
Gene Symbol:C8orf58 ( FLJ34715 )
Gene Full Name: chromosome 8 open reading frame 58
Band: 8p21.3
Quick LinksEntrez ID:541565; OMIM: NA; Uniprot ID:CH058_HUMAN; ENSEMBL ID: ENSG00000120913,ENSG00000241852; HGNC ID: 32233
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus10 / 56401217
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor14 / 26384553
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow0 / 488010 
brain14 / 110098912
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine1 / 2344724
kidney3 / 21177714
larynx0 / 241450 
liver3 / 20774314
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary7 / 10205168
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P305321
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.7 ± 1.07
Basal Forebrain2.29 ± 0.25
Basal Part of Pons1.87 ± 0.41
Cerebellar Cortex2.3 ± 0.9
Cerebellar Nuclei2.55 ± 0.7
Claustrum3.18 ± 0.87
Epithalamus2.2 ± 0.77
Frontal Lobe2.12 ± 0.61
Globus Pallidus2.72 ± 0.31
Hypothalamus2.26 ± 0.65
Insula2.03 ± 0.42
Limbic Lobe2.3 ± 0.61
Mesencephalon2.47 ± 0.67
Myelencephalon2.38 ± 0.61
Occipital Lobe2.36 ± 0.68
Parietal Lobe2.42 ± 0.68
Pontine Tegmentum2.3 ± 0.71
Striatum2.43 ± 0.55
Subthalamus2.48 ± 0.73
Temporal Lobe2.18 ± 0.66
Thalamus2.27 ± 0.67
White Matter2.66 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
9930012K11RikCBCerebellum0.67
0.91
9930012K11RikCTXCerebral cortex0.53
0.78
9930012K11RikHIPHippocampal region0.18
0.27
9930012K11RikHPFHippocampal formation0.25
0.47
9930012K11RikHYHypothalamus0.05
0.03
9930012K11RikLSXLateral septal complex0.26
0.2
9930012K11RikMBMidbrain0.24
0.33
9930012K11RikMYMedulla1.12
1.22
9930012K11RikOLFOlfactory bulb0.61
0.5
9930012K11RikPPons0.49
0.61
9930012K11RikPALPallidum0.1
0.1
9930012K11RikRHPRetrohippocampal region0.37
0.79
9930012K11RiksAMYStriatum-like amygdalar nuclei0.03
0
9930012K11RikSTRStriatum0.16
0.19
9930012K11RikSTRdStriatum dorsal region0.1
0.11
9930012K11RikSTRvStriatum ventral region0.07
0.03
9930012K11RikTHThalamus0.11
0.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018