AutismKB 2.0

Annotation Detail for KCNK10


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Basic Information Top
Gene Symbol:KCNK10 ( FLJ43399,K2p10.1,TREK-2,TREK2 )
Gene Full Name: potassium channel, subfamily K, member 10
Band: 14q31.3
Quick LinksEntrez ID:54207; OMIM: 605873; Uniprot ID:KCNKA_HUMAN; ENSEMBL ID: ENSG00000100433; HGNC ID: 6273
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal31 / 33603079
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain22 / 110098919
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220727_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.15
Adipocyte7.9
AdrenalCortex8.85
Adrenalgland6.7
Amygdala8.6
Appendix8
AtrioventricularNode6.3
BDCA4+_DentriticCells190.55
Bonemarrow7.85
BronchialEpithelialCells7.7
CD105+_Endothelial8.2
CD14+_Monocytes8.45
CD19+_BCells(neg._sel.)8.55
CD33+_Myeloid10.5
CD34+10.5
CD4+_Tcells8.95
CD56+_NKCells9.7
CD71+_EarlyErythroid7.6
CD8+_Tcells7.45
CardiacMyocytes19.95
Caudatenucleus7.05
Cerebellum6.45
CerebellumPeduncles9.25
CiliaryGanglion6.1
CingulateCortex16.05
Colorectaladenocarcinoma7.95
DorsalRootGanglion6.7
FetalThyroid7.8
Fetalbrain8.4
Fetalliver6.95
Fetallung4.4
GlobusPallidus9.2
Heart12.8
Hypothalamus8.85
Kidney6.45
Leukemia_chronicMyelogenousK-5627.2
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6.5
Liver11.2
Lung7.4
Lymphnode7
Lymphoma_burkitts(Daudi)10.15
Lymphoma_burkitts(Raji)11.4
MedullaOblongata7.3
OccipitalLobe7.4
OlfactoryBulb6.25
Ovary6.15
Pancreas6.65
PancreaticIslet8.6
ParietalLobe8.55
Pituitary9.4
Placenta6.45
Pons8.25
PrefrontalCortex10.05
Prostate9.2
Salivarygland7.7
SkeletalMuscle13.8
Skin6.55
SmoothMuscle9.05
Spinalcord8.5
SubthalamicNucleus9.95
SuperiorCervicalGanglion10.6
TemporalLobe9.25
Testis6.9
TestisGermCell6.4
TestisIntersitial8.75
TestisLeydigCell11.9
TestisSeminiferousTubule6.9
Thalamus8.15
Thymus5.4
Thyroid9.55
Tongue8.7
Tonsil8.3
Trachea6.7
TrigeminalGanglion8.15
Uterus6.55
UterusCorpus7.15
WholeBlood7.8
Wholebrain6.85
colon8.1
pineal_day11.56
pineal_night9.84
retina9.775
small_intestine7.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_391_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.83 ± 1.05
Basal Forebrain2.34 ± 0.29
Basal Part of Pons2.05 ± 0.32
Cerebellar Cortex3.14 ± 0.47
Cerebellar Nuclei2.74 ± 0.64
Claustrum3.22 ± 0.82
Epithalamus2.14 ± 0.83
Frontal Lobe2.35 ± 0.78
Globus Pallidus2.2 ± 0.42
Hypothalamus2.47 ± 0.62
Insula2.59 ± 0.89
Limbic Lobe2.52 ± 0.69
Mesencephalon2.53 ± 0.71
Myelencephalon2.49 ± 0.75
Occipital Lobe2.33 ± 0.63
Parietal Lobe2.4 ± 0.79
Pontine Tegmentum2.6 ± 0.92
Striatum2.05 ± 0.64
Subthalamus2.59 ± 0.81
Temporal Lobe2.39 ± 0.84
Thalamus2.32 ± 0.67
White Matter2.38 ± 0.2
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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