AutismKB 2.0

Annotation Detail for GPR173


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Basic Information Top
Gene Symbol:GPR173 ( SREB3 )
Gene Full Name: G protein-coupled receptor 173
Band: Xp11.22
Quick LinksEntrez ID:54328; OMIM: 300253; Uniprot ID:GP173_HUMAN; ENSEMBL ID: ENSG00000184194; HGNC ID: 18186
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal24 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221299_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.9
Adipocyte3.8
AdrenalCortex4
Adrenalgland3.25
Amygdala4.05
Appendix3.85
AtrioventricularNode3
BDCA4+_DentriticCells4.35
Bonemarrow3.75
BronchialEpithelialCells3.85
CD105+_Endothelial3.9
CD14+_Monocytes4.1
CD19+_BCells(neg._sel.)4.15
CD33+_Myeloid5
CD34+4.95
CD4+_Tcells4.25
CD56+_NKCells4.6
CD71+_EarlyErythroid3.6
CD8+_Tcells3.7
CardiacMyocytes4.95
Caudatenucleus3.45
Cerebellum3.1
CerebellumPeduncles4.3
CiliaryGanglion2.75
CingulateCortex3.95
Colorectaladenocarcinoma3.9
DorsalRootGanglion3.1
FetalThyroid3.75
Fetalbrain3.85
Fetalliver3.3
Fetallung3.25
GlobusPallidus2.85
Heart5.65
Hypothalamus4.25
Kidney3.2
Leukemia_chronicMyelogenousK-5623.5
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5.05
Lung4.3
Lymphnode3.35
Lymphoma_burkitts(Daudi)4.95
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.55
OccipitalLobe3.45
OlfactoryBulb3.05
Ovary2.55
Pancreas3.1
PancreaticIslet4.15
ParietalLobe4.05
Pituitary4.55
Placenta4
Pons3.65
PrefrontalCortex4.8
Prostate4.5
Salivarygland3.1
SkeletalMuscle4.45
Skin2.95
SmoothMuscle4.45
Spinalcord4.15
SubthalamicNucleus3.5
SuperiorCervicalGanglion4.5
TemporalLobe3.5
Testis3.3
TestisGermCell3.25
TestisIntersitial3.25
TestisLeydigCell3.8
TestisSeminiferousTubule3.3
Thalamus3.9
Thymus3.05
Thyroid4.85
Tongue3.8
Tonsil3.8
Trachea3.2
TrigeminalGanglion4
Uterus3.2
UterusCorpus3.6
WholeBlood4.25
Wholebrain3.35
colon3.85
pineal_day4.84
pineal_night4.74
retina4.675
small_intestine3.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10371_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.79 ± 0.56
Basal Forebrain3.47 ± 0.3
Basal Part of Pons3.5 ± 0.59
Cerebellar Cortex3.76 ± 0.3
Cerebellar Nuclei3.12 ± 0.42
Claustrum3.5 ± 0.58
Epithalamus3.11 ± 0.3
Frontal Lobe3.24 ± 0.63
Globus Pallidus3.73 ± 0.72
Hypothalamus3.35 ± 0.66
Insula3.46 ± 0.45
Limbic Lobe3.6 ± 0.5
Mesencephalon3.22 ± 0.61
Myelencephalon3.43 ± 0.56
Occipital Lobe3.41 ± 0.55
Parietal Lobe3.34 ± 0.61
Pontine Tegmentum3.21 ± 0.64
Striatum3.23 ± 0.62
Subthalamus3.39 ± 0.87
Temporal Lobe3.43 ± 0.54
Thalamus3.23 ± 0.62
White Matter4.2 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr173CBCerebellum46.29
60.85
Gpr173CTXCerebral cortex46.84
34.93
Gpr173HIPHippocampal region27.06
37.94
Gpr173HPFHippocampal formation28.64
31.22
Gpr173HYHypothalamus29.73
24.75
Gpr173LSXLateral septal complex49.72
38.33
Gpr173MBMidbrain25.37
22.47
Gpr173MYMedulla32.86
31.8
Gpr173OLFOlfactory bulb56.78
52.56
Gpr173PPons24.33
23.93
Gpr173PALPallidum25.1
21.38
Gpr173RHPRetrohippocampal region31.93
23.65
Gpr173sAMYStriatum-like amygdalar nuclei22.52
17.37
Gpr173STRStriatum32.64
25.11
Gpr173STRdStriatum dorsal region28
21.5
Gpr173STRvStriatum ventral region45.52
33.26
Gpr173THThalamus31.9
26.49
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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