Annotation Detail for GNG2
Basic Information Top
| Gene Symbol: | GNG2 ( - ) |
|---|---|
| Gene Full Name: | guanine nucleotide binding protein (G protein), gamma 2 |
| Band: | 14q22.1 |
| Quick Links | Entrez ID:54331; OMIM: 606981; Uniprot ID:GBG2_HUMAN; ENSEMBL ID: ENSG00000186469; HGNC ID: 4404 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.723399
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 221 / 564012 | 391 |  |
| neonate | 2 / 31097 | 64 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 5 / 55556 | 89 | |
| adult | 66 / 1939121 | 34 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 2 / 1939121 | 1 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 4 / 1939121 | 2 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 30 / 263845 | 113 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 8 / 136302 | 58 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 12 / 95842 | 125 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 466 / 3360307 | 138 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 9 / 125680 | 71 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 7 / 124949 | 56 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 1 / 90257 | 11 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 5 / 3360307 | 1 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 18 / 3360307 | 5 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 9 / 123478 | 72 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 390 / 1100989 | 354 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 6 / 16212 | 370 | |
| embryonic tissue | 13 / 215722 | 60 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 15 / 91610 | 163 | |
| mammary gland | 3 / 153271 | 19 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 5 / 15768 | 317 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 8 / 214812 | 37 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 9 / 210574 | 42 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 1 / 96619 | 10 | |
| testis | 58 / 330442 | 175 | |
| thymus | 14 / 81131 | 172 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 1 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 8 / 1100989 | 7 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 3 / 330442 | 9 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: A_23_P32536
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.73 ± 0.45 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.53 ± 0.35 | |
| Basal Part of Pons | 5.3 ± 0.8 | |
| Cerebellar Cortex | 6.35 ± 0.54 | |
| Cerebellar Nuclei | 5.3 ± 0.67 | |
| Claustrum | 8.51 ± 0.38 | |
| Epithalamus | 5.66 ± 0.71 | |
| Frontal Lobe | 6.8 ± 0.58 | |
| Globus Pallidus | 5.88 ± 0.82 | |
| Hypothalamus | 7.41 ± 0.81 | |
| Insula | 7.17 ± 0.33 | |
| Limbic Lobe | 7.16 ± 0.44 | |
| Mesencephalon | 6.6 ± 0.8 | |
| Myelencephalon | 6.64 ± 0.92 | |
| Occipital Lobe | 5.89 ± 0.91 | |
| Parietal Lobe | 6.7 ± 0.66 | |
| Pontine Tegmentum | 7.06 ± 0.6 | |
| Striatum | 5.14 ± 1.08 | |
| Subthalamus | 7.18 ± 0.24 | |
| Temporal Lobe | 7.13 ± 0.61 | |
| Thalamus | 6.35 ± 0.57 | |
| White Matter | 4.95 ± 0.74 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gng2 | CB | Cerebellum | 5.16 | |
| 6.74 | | |||
| Gng2 | CTX | Cerebral cortex | 20.15 | |
| 16.4 | | |||
| Gng2 | HIP | Hippocampal region | 44.19 | |
| 66.63 | | |||
| Gng2 | HPF | Hippocampal formation | 33.33 | |
| 46.41 | | |||
| Gng2 | HY | Hypothalamus | 13.16 | |
| 12.32 | | |||
| Gng2 | LSX | Lateral septal complex | 19.32 | |
| 16.13 | | |||
| Gng2 | MB | Midbrain | 13.11 | |
| 13.85 | | |||
| Gng2 | MY | Medulla | 8.39 | |
| 10.28 | | |||
| Gng2 | OLF | Olfactory bulb | 11.15 | |
| 8.75 | | |||
| Gng2 | P | Pons | 17.77 | |
| 21.43 | | |||
| Gng2 | PAL | Pallidum | 8.39 | |
| 7.08 | | |||
| Gng2 | RHP | Retrohippocampal region | 18.2 | |
| 16.16 | | |||
| Gng2 | sAMY | Striatum-like amygdalar nuclei | 17.22 | |
| 12.63 | | |||
| Gng2 | STR | Striatum | 6.19 | |
| 5.19 | | |||
| Gng2 | STRd | Striatum dorsal region | 3.89 | |
| 3.74 | | |||
| Gng2 | STRv | Striatum ventral region | 4.03 | |
| 3.01 | | |||
| Gng2 | TH | Thalamus | 7.55 | |
| 6.35 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GBG2_HUMAN_1 | 12 | 1 | 12 | ASNNTASIAQAR | PRIDE |
| PAp00000122 | 14 | 33 | 46 | AAADLMAYCEAHAK | Peptide Atlas |