AutismKB 2.0

Annotation Detail for SSH1


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Basic Information Top
Gene Symbol:SSH1 ( FLJ21928,FLJ38102,KIAA1298,SSH1L )
Gene Full Name: slingshot homolog 1 (Drosophila)
Band: 12q24.11
Quick LinksEntrez ID:54434; OMIM: 606778; Uniprot ID:SSH1_HUMAN; ENSEMBL ID: ENSG00000084112; HGNC ID: 30579
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus35 / 56401262
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult94 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor6 / 6895987
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal161 / 336030747
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor21 / 124949168
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone4 / 7165555
bone marrow1 / 4880120
brain33 / 110098929
cervix0 / 481710 
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye33 / 211054156
heart3 / 8962633
intestine5 / 23447221
kidney9 / 21177742
larynx0 / 241450 
liver6 / 20774328
lung17 / 33697450
lymph0 / 442700 
lymph node5 / 9161054
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate8 / 18934542
salivary gland0 / 201550 
skin23 / 210574109
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus2 / 8113124
thyroid3 / 4747363
tonsil6 / 16999352
trachea2 / 5241338
umbilical cord1 / 1368073
uterus21 / 23287890
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221752_at
Cell line Expression level Expression bar
721_B_lymphoblasts94.3
Adipocyte35.85
AdrenalCortex27.3
Adrenalgland22.45
Amygdala35.8
Appendix28.8
AtrioventricularNode21.9
BDCA4+_DentriticCells32.95
Bonemarrow23.25
BronchialEpithelialCells58.65
CD105+_Endothelial23.8
CD14+_Monocytes46.5
CD19+_BCells(neg._sel.)40.25
CD33+_Myeloid72.45
CD34+37.2
CD4+_Tcells33
CD56+_NKCells199.85
CD71+_EarlyErythroid18.95
CD8+_Tcells34.35
CardiacMyocytes68.75
Caudatenucleus21.7
Cerebellum55.8
CerebellumPeduncles37.4
CiliaryGanglion18.55
CingulateCortex26.75
Colorectaladenocarcinoma56.25
DorsalRootGanglion20.5
FetalThyroid32.25
Fetalbrain26.65
Fetalliver12.35
Fetallung27.7
GlobusPallidus19.25
Heart38
Hypothalamus37.9
Kidney22.1
Leukemia_chronicMyelogenousK-56218.2
Leukemia_promyelocytic-HL-6021.35
Leukemialymphoblastic(MOLT-4)16.25
Liver35.45
Lung76.1
Lymphnode27.3
Lymphoma_burkitts(Daudi)31.35
Lymphoma_burkitts(Raji)37.05
MedullaOblongata22.2
OccipitalLobe24.95
OlfactoryBulb56.6
Ovary18.25
Pancreas21.15
PancreaticIslet46.55
ParietalLobe28.7
Pituitary28.1
Placenta29.45
Pons24.7
PrefrontalCortex49.2
Prostate42.15
Salivarygland18.7
SkeletalMuscle39.8
Skin18.05
SmoothMuscle118.6
Spinalcord29.1
SubthalamicNucleus24.95
SuperiorCervicalGanglion30.7
TemporalLobe24.55
Testis22.15
TestisGermCell28.45
TestisIntersitial22
TestisLeydigCell25.75
TestisSeminiferousTubule27.05
Thalamus25.1
Thymus23.55
Thyroid35.4
Tongue26.05
Tonsil27.1
Trachea22
TrigeminalGanglion30.55
Uterus52.2
UterusCorpus38.15
WholeBlood73.6
Wholebrain37.65
colon24.15
pineal_day87.7
pineal_night89.54
retina51.9
small_intestine23.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P333802
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.84 ± 0.54
Basal Forebrain4.72 ± 0.32
Basal Part of Pons5.2 ± 0.47
Cerebellar Cortex5.42 ± 0.22
Cerebellar Nuclei4.71 ± 0.47
Claustrum4.67 ± 0.53
Epithalamus4.38 ± 0.68
Frontal Lobe4.91 ± 0.5
Globus Pallidus4.07 ± 0.6
Hypothalamus4.74 ± 0.75
Insula5.06 ± 0.38
Limbic Lobe5.07 ± 0.56
Mesencephalon4.88 ± 0.57
Myelencephalon4.86 ± 0.57
Occipital Lobe5.15 ± 0.45
Parietal Lobe5.02 ± 0.61
Pontine Tegmentum4.84 ± 0.62
Striatum4.2 ± 0.46
Subthalamus5.1 ± 0.59
Temporal Lobe5.04 ± 0.43
Thalamus4.89 ± 0.53
White Matter3.19 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ssh1CBCerebellum34.18
41.49
Ssh1CTXCerebral cortex45.1
33.64
Ssh1HIPHippocampal region23.41
24.56
Ssh1HPFHippocampal formation31.96
30.69
Ssh1HYHypothalamus22.76
21.41
Ssh1LSXLateral septal complex42.16
45.16
Ssh1MBMidbrain11.11
9.89
Ssh1MYMedulla21.86
22.07
Ssh1OLFOlfactory bulb45.38
38.72
Ssh1PPons13.29
14.05
Ssh1PALPallidum29.79
27.75
Ssh1RHPRetrohippocampal region44.65
38.15
Ssh1sAMYStriatum-like amygdalar nuclei48.76
40.34
Ssh1STRStriatum21.5
17.79
Ssh1STRdStriatum dorsal region14.27
10.96
Ssh1STRvStriatum ventral region27.68
21.7
Ssh1THThalamus22.23
21.04
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00538179 24 9 32 SPTPSAASSSASNSELEAGSEEDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018