AutismKB 2.0

Annotation Detail for SH3TC1


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Basic Information Top
Gene Symbol:SH3TC1 ( FLJ20356,FLJ32999,FLJ36243,FLJ46394 )
Gene Full Name: SH3 domain and tetratricopeptide repeats 1
Band: 4p16.1
Quick LinksEntrez ID:54436; OMIM: NA; Uniprot ID:S3TC1_HUMAN; ENSEMBL ID: ENSG00000125089; HGNC ID: 26009
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma8 / 10688374
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal91 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood6 / 12347848
bone0 / 716550 
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine5 / 23447221
kidney20 / 21177794
larynx2 / 2414582
liver2 / 2077439
lung11 / 33697432
lymph0 / 442700 
lymph node7 / 9161076
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas21 / 21481297
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen3 / 5395255
stomach1 / 9661910
testis1 / 3304423
thymus38 / 81131468
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord3 / 13680219
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13762_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.9 ± 1.03
Basal Forebrain1.51 ± 0.23
Basal Part of Pons1.18 ± 0.38
Cerebellar Cortex1.36 ± 0.74
Cerebellar Nuclei1.87 ± 0.81
Claustrum2.26 ± 0.79
Epithalamus1.31 ± 0.68
Frontal Lobe1.35 ± 0.64
Globus Pallidus2.06 ± 0.26
Hypothalamus1.55 ± 0.7
Insula1.26 ± 0.45
Limbic Lobe1.52 ± 0.61
Mesencephalon1.68 ± 0.7
Myelencephalon1.55 ± 0.67
Occipital Lobe1.46 ± 0.62
Parietal Lobe1.56 ± 0.77
Pontine Tegmentum1.51 ± 0.67
Striatum1.66 ± 0.58
Subthalamus1.56 ± 0.6
Temporal Lobe1.39 ± 0.7
Thalamus1.44 ± 0.62
White Matter1.87 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sh3tc1CBCerebellum0.58
0.93
Sh3tc1CTXCerebral cortex0.73
0.69
Sh3tc1HIPHippocampal region0.17
0.14
Sh3tc1HPFHippocampal formation0.17
0.12
Sh3tc1HYHypothalamus0.27
0.42
Sh3tc1LSXLateral septal complex0
0
Sh3tc1MBMidbrain0.46
0.72
Sh3tc1MYMedulla1.34
1.74
Sh3tc1OLFOlfactory bulb1.27
1.99
Sh3tc1PPons0.41
0.48
Sh3tc1PALPallidum0.11
0.11
Sh3tc1RHPRetrohippocampal region0.14
0.08
Sh3tc1sAMYStriatum-like amygdalar nuclei0.11
0.13
Sh3tc1STRStriatum0.17
0.22
Sh3tc1STRdStriatum dorsal region0.12
0.12
Sh3tc1STRvStriatum ventral region0.09
0.04
Sh3tc1THThalamus0.46
0.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018