Annotation Detail for FBXW5
Basic Information Top
| Gene Symbol: | FBXW5 ( DKFZp434B205,Fbw5,MGC20962,RP11-229P13.10 ) |
|---|---|
| Gene Full Name: | F-box and WD repeat domain containing 5 |
| Band: | 9q34.3 |
| Quick Links | Entrez ID:54461; OMIM: 609072; Uniprot ID:FBXW5_HUMAN; ENSEMBL ID: ENSG00000159069; HGNC ID: 13613 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.522507
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 8 / 70761 | 113 |  |
| blastocyst | 4 / 62319 | 64 | |
| fetus | 23 / 564012 | 40 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 162 / 1939121 | 83 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 8 / 34366 | 232 |  |
| chondrosarcoma | 15 / 82823 | 181 | |
| colorectal tumor | 13 / 114246 | 113 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 18 / 119369 | 150 | |
| germ cell tumor | 25 / 263845 | 94 | |
| glioma | 13 / 106883 | 121 | |
| head and neck tumor | 6 / 136302 | 44 | |
| kidney tumor | 12 / 68959 | 174 | |
| leukemia | 12 / 95842 | 125 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 23 / 103127 | 223 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 216 / 3360307 | 64 | |
| ovarian tumor | 13 / 76682 | 169 | |
| pancreatic tumor | 11 / 104616 | 105 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 7 / 102680 | 68 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 14 / 124949 | 112 | |
| soft tissue/muscle tissue tumor | 12 / 125191 | 95 | |
| uterine tumor | 11 / 90257 | 121 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 10 / 40015 | 249 | |
| bladder | 1 / 29757 | 33 | |
| blood | 16 / 123478 | 129 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 70 / 1100989 | 63 | |
| cervix | 19 / 48171 | 394 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 13 / 215722 | 60 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 24 / 211054 | 113 | |
| heart | 2 / 89626 | 22 | |
| intestine | 20 / 234472 | 85 | |
| kidney | 22 / 211777 | 103 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 |  |
| lung | 40 / 336974 | 118 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 3 / 91610 | 32 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 14 / 102051 | 137 | |
| pancreas | 16 / 214812 | 74 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 27 / 280825 | 96 | |
| prostate | 15 / 189345 | 79 | |
| salivary gland | 6 / 20155 | 297 | |
| skin | 23 / 210574 | 109 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 7 / 96619 | 72 | |
| testis | 51 / 330442 | 154 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_14773_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.47 ± 0.67 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.68 ± 0.57 | |
| Basal Part of Pons | 6.13 ± 0.8 | |
| Cerebellar Cortex | 6.14 ± 0.63 | |
| Cerebellar Nuclei | 4.88 ± 0.48 | |
| Claustrum | 4.81 ± 1.06 | |
| Epithalamus | 5.65 ± 0.9 | |
| Frontal Lobe | 6.1 ± 0.7 | |
| Globus Pallidus | 4.73 ± 0.55 | |
| Hypothalamus | 5.65 ± 0.72 | |
| Insula | 6.15 ± 0.45 | |
| Limbic Lobe | 5.72 ± 0.81 | |
| Mesencephalon | 5.67 ± 0.66 | |
| Myelencephalon | 5.72 ± 0.76 | |
| Occipital Lobe | 5.13 ± 0.79 | |
| Parietal Lobe | 5.78 ± 0.69 | |
| Pontine Tegmentum | 5.65 ± 0.74 | |
| Striatum | 4.95 ± 0.73 | |
| Subthalamus | 5.65 ± 0.67 | |
| Temporal Lobe | 6.05 ± 0.57 | |
| Thalamus | 5.83 ± 0.5 | |
| White Matter | 4.72 ± 0.61 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Fbxw5 | CB | Cerebellum | 33.65 | |
| 91.65 | | |||
| Fbxw5 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Fbxw5 | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Fbxw5 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Fbxw5 | HY | Hypothalamus | 77.01 | |
| 87.54 | | |||
| Fbxw5 | LSX | Lateral septal complex | 63.18 | |
| 60.85 | | |||
| Fbxw5 | MB | Midbrain | 91.77 | |
| 100 | | |||
| Fbxw5 | MY | Medulla | 54.87 | |
| 100 | | |||
| Fbxw5 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Fbxw5 | P | Pons | 62.36 | |
| 100 | | |||
| Fbxw5 | PAL | Pallidum | 56.84 | |
| 60.91 | | |||
| Fbxw5 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Fbxw5 | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Fbxw5 | STR | Striatum | 98.17 | |
| 100 | | |||
| Fbxw5 | STRd | Striatum dorsal region | 94.28 | |
| 94.72 | | |||
| Fbxw5 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Fbxw5 | TH | Thalamus | 84.09 | |
| 99.53 | |