Annotation Detail for XRN1
Basic Information Top
| Gene Symbol: | XRN1 ( DKFZp434P0721,DKFZp686B22225,DKFZp686F19113,FLJ41903,SEP1 ) |
|---|---|
| Gene Full Name: | 5'-3' exoribonuclease 1 |
| Band: | 3q23 |
| Quick Links | Entrez ID:54464; OMIM: 607994; Uniprot ID:XRN1_HUMAN; ENSEMBL ID: ENSG00000114127; HGNC ID: 30654 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.435103
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 30 / 564012 | 53 | |
| neonate | 2 / 31097 | 64 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 1 / 55556 | 17 | |
| adult | 80 / 1939121 | 41 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 2 / 263845 | 7 |  |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 121 / 3360307 | 36 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 10 / 125191 | 79 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 8 / 123478 | 64 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 17 / 1100989 | 15 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 9 / 336974 | 26 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 19 / 153271 | 123 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 14 / 214812 | 65 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 8 / 280825 | 28 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 6 / 96619 | 62 | |
| testis | 9 / 330442 | 27 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 11 / 232878 | 47 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_24_P393353
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.17 ± 0.28 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.18 ± 0.18 | |
| Basal Part of Pons | 4.99 ± 0.4 | |
| Cerebellar Cortex | 5.39 ± 0.24 | |
| Cerebellar Nuclei | 4.69 ± 0.54 | |
| Claustrum | 5.2 ± 0.6 | |
| Epithalamus | 5.29 ± 0.24 | |
| Frontal Lobe | 4.89 ± 0.31 | |
| Globus Pallidus | 5.15 ± 0.33 | |
| Hypothalamus | 4.84 ± 0.48 | |
| Insula | 5.03 ± 0.34 | |
| Limbic Lobe | 5.12 ± 0.42 | |
| Mesencephalon | 5.03 ± 0.39 | |
| Myelencephalon | 5.05 ± 0.38 | |
| Occipital Lobe | 5.48 ± 0.46 | |
| Parietal Lobe | 5.07 ± 0.36 | |
| Pontine Tegmentum | 5.02 ± 0.41 | |
| Striatum | 5.17 ± 0.42 | |
| Subthalamus | 4.62 ± 0.31 | |
| Temporal Lobe | 5.01 ± 0.37 | |
| Thalamus | 5.01 ± 0.39 | |
| White Matter | 6.1 ± 0.42 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Xrn1 | CB | Cerebellum | 6.85 | |
| 6.61 | | |||
| Xrn1 | CTX | Cerebral cortex | 5.98 | |
| 4.56 | | |||
| Xrn1 | HIP | Hippocampal region | 15.93 | |
| 16.43 | | |||
| Xrn1 | HPF | Hippocampal formation | 12.05 | |
| 11.27 | | |||
| Xrn1 | HY | Hypothalamus | 2.7 | |
| 2.34 | | |||
| Xrn1 | LSX | Lateral septal complex | 4.09 | |
| 2.81 | | |||
| Xrn1 | MB | Midbrain | 2.18 | |
| 1.89 | | |||
| Xrn1 | MY | Medulla | 5.37 | |
| 4.98 | | |||
| Xrn1 | OLF | Olfactory bulb | 12.96 | |
| 10.8 | | |||
| Xrn1 | P | Pons | 4.41 | |
| 3.75 | | |||
| Xrn1 | PAL | Pallidum | 2.46 | |
| 1.76 | | |||
| Xrn1 | RHP | Retrohippocampal region | 5.83 | |
| 4.43 | | |||
| Xrn1 | sAMY | Striatum-like amygdalar nuclei | 2.5 | |
| 2.89 | | |||
| Xrn1 | STR | Striatum | 3.35 | |
| 2.56 | | |||
| Xrn1 | STRd | Striatum dorsal region | 2.46 | |
| 2.03 | | |||
| Xrn1 | STRv | Striatum ventral region | 6.02 | |
| 3.78 | | |||
| Xrn1 | TH | Thalamus | 2.92 | |
| 2.56 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00010422 | 16 | 1449 | 1464 | ICSLVGMPQPDFSFLR | Peptide Atlas |