AutismKB 2.0

Annotation Detail for PRMT7


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Basic Information Top
Gene Symbol:PRMT7 ( FLJ10640,KIAA1933 )
Gene Full Name: protein arginine methyltransferase 7
Band: 16q22.1
Quick LinksEntrez ID:54496; OMIM: 610087; Uniprot ID:ANM7_HUMAN; ENSEMBL ID: ENSG00000132600; HGNC ID: 25557
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst7 / 62319112
fetus22 / 56401239
neonate2 / 3109764
infant1 / 2362042
juvenile6 / 55556107
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor19 / 26384572
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia10 / 95842104
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal165 / 336030749
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone3 / 7165541
bone marrow4 / 4880181
brain68 / 110098961
cervix3 / 4817162
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye9 / 21105442
heart1 / 8962611
intestine13 / 23447255
kidney7 / 21177733
larynx2 / 2414582
liver6 / 20774328
lung16 / 33697447
lymph3 / 4427067
lymph node0 / 916100 
mammary gland8 / 15327152
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate15 / 18934579
salivary gland0 / 201550 
skin9 / 21057442
spleen8 / 53952148
stomach4 / 9661941
testis14 / 33044242
thymus25 / 81131308
thyroid1 / 4747321
tonsil1 / 1699958
trachea3 / 5241357
umbilical cord0 / 136800 
uterus9 / 23287838
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219408_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte4.6
AdrenalCortex4.95
Adrenalgland3.9
Amygdala4.85
Appendix4.65
AtrioventricularNode3.55
BDCA4+_DentriticCells10.4
Bonemarrow4.65
BronchialEpithelialCells4.6
CD105+_Endothelial5.1
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)5
CD33+_Myeloid5.95
CD34+6.05
CD4+_Tcells5.2
CD56+_NKCells5.6
CD71+_EarlyErythroid4.35
CD8+_Tcells5
CardiacMyocytes6.45
Caudatenucleus4.15
Cerebellum3.75
CerebellumPeduncles5.25
CiliaryGanglion3.35
CingulateCortex4.7
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.5
FetalThyroid4.5
Fetalbrain4.55
Fetalliver4
Fetallung3.85
GlobusPallidus3.45
Heart6.35
Hypothalamus5.1
Kidney3.75
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.7
Liver6.1
Lung5.2
Lymphnode3.95
Lymphoma_burkitts(Daudi)5.85
Lymphoma_burkitts(Raji)6.45
MedullaOblongata4.2
OccipitalLobe4.15
OlfactoryBulb3.65
Ovary3.05
Pancreas3.7
PancreaticIslet4.9
ParietalLobe4.9
Pituitary5.4
Placenta4.75
Pons4.4
PrefrontalCortex5.8
Prostate5.35
Salivarygland3.7
SkeletalMuscle5.6
Skin3.55
SmoothMuscle5.25
Spinalcord4.95
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.15
TemporalLobe4.2
Testis4
TestisGermCell3.75
TestisIntersitial3.8
TestisLeydigCell4.55
TestisSeminiferousTubule3.9
Thalamus4.7
Thymus4.5
Thyroid5.9
Tongue4.5
Tonsil4.5
Trachea3.85
TrigeminalGanglion4.55
Uterus3.75
UterusCorpus4.15
WholeBlood5.1
Wholebrain4.05
colon4.65
pineal_day5.92
pineal_night5.68
retina5.6
small_intestine4.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P77437
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.67 ± 0.64
Basal Forebrain3.43 ± 0.75
Basal Part of Pons3.48 ± 0.58
Cerebellar Cortex3.68 ± 0.47
Cerebellar Nuclei3.22 ± 0.49
Claustrum3.67 ± 0.72
Epithalamus2.93 ± 0.59
Frontal Lobe3.39 ± 0.59
Globus Pallidus3 ± 0.79
Hypothalamus3.35 ± 0.38
Insula3.33 ± 0.47
Limbic Lobe3.45 ± 0.6
Mesencephalon3.25 ± 0.61
Myelencephalon3.38 ± 0.58
Occipital Lobe3.22 ± 0.71
Parietal Lobe3.39 ± 0.49
Pontine Tegmentum3.39 ± 0.66
Striatum3.25 ± 0.58
Subthalamus3.21 ± 0.71
Temporal Lobe3.35 ± 0.7
Thalamus3.28 ± 0.63
White Matter2.94 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prmt7CBCerebellum7.13
9.21
Prmt7CTXCerebral cortex3.22
2.64
Prmt7HIPHippocampal region7.32
7.43
Prmt7HPFHippocampal formation5.81
5.45
Prmt7HYHypothalamus1.56
1.6
Prmt7LSXLateral septal complex0
0
Prmt7MBMidbrain2.47
3.18
Prmt7MYMedulla4.28
6.99
Prmt7OLFOlfactory bulb4.21
3.94
Prmt7PPons3.06
4.61
Prmt7PALPallidum0.59
0.66
Prmt7RHPRetrohippocampal region3.49
2.89
Prmt7sAMYStriatum-like amygdalar nuclei0.38
0.31
Prmt7STRStriatum0.34
0.31
Prmt7STRdStriatum dorsal region0.21
0.17
Prmt7STRvStriatum ventral region0.86
0.82
Prmt7THThalamus1.94
2.24
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00499355 16 122 137 HSTEVTVGPEGDMPCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018