Annotation Detail for POU2F1
Basic Information Top
| Gene Symbol: | POU2F1 ( OCT1,OTF1 ) |
|---|---|
| Gene Full Name: | POU class 2 homeobox 1 |
| Band: | 1q24.2 |
| Quick Links | Entrez ID:5451; OMIM: 164175; Uniprot ID:PO2F1_HUMAN; ENSEMBL ID: ENSG00000143190; HGNC ID: 9212 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.283402
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 12 / 564012 | 21 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 42 / 1939121 | 21 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 68 / 3360307 | 20 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 18 / 1100989 | 16 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 0 / 89626 | 0 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 5 / 336974 | 14 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 6 / 330442 | 18 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 206789_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 28.15 | |
| Adipocyte | 6.05 | |
| AdrenalCortex | 6.45 | |
| Adrenalgland | 5.2 | |
| Amygdala | 6.45 | |
| Appendix | 6.2 | |
| AtrioventricularNode | 4.95 | |
| BDCA4+_DentriticCells | 7.55 | |
| Bonemarrow | 6.45 | |
| BronchialEpithelialCells | 6.15 | |
| CD105+_Endothelial | 6.3 | |
| CD14+_Monocytes | 6.65 | |
| CD19+_BCells(neg._sel.) | 10.6 | |
| CD33+_Myeloid | 7.9 | |
| CD34+ | 13.8 | |
| CD4+_Tcells | 6.85 | |
| CD56+_NKCells | 7.2 | |
| CD71+_EarlyErythroid | 5.8 | |
| CD8+_Tcells | 6.15 | |
| CardiacMyocytes | 7.9 | |
| Caudatenucleus | 5.5 | |
| Cerebellum | 5.1 | |
| CerebellumPeduncles | 7 | |
| CiliaryGanglion | 4.5 | |
| CingulateCortex | 6.5 | |
| Colorectaladenocarcinoma | 6.2 | |
| DorsalRootGanglion | 4.7 | |
| FetalThyroid | 6.1 | |
| Fetalbrain | 6.1 | |
| Fetalliver | 5.55 | |
| Fetallung | 5.1 | |
| GlobusPallidus | 4.45 | |
| Heart | 7.75 | |
| Hypothalamus | 6.65 | |
| Kidney | 4.9 | |
| Leukemia_chronicMyelogenousK-562 | 5.6 | |
| Leukemia_promyelocytic-HL-60 | 5.45 | |
| Leukemialymphoblastic(MOLT-4) | 4.95 | |
| Liver | 8.1 | |
| Lung | 6.95 | |
| Lymphnode | 5.35 | |
| Lymphoma_burkitts(Daudi) | 7.9 | |
| Lymphoma_burkitts(Raji) | 8.8 | |
| MedullaOblongata | 5.65 | |
| OccipitalLobe | 5.6 | |
| OlfactoryBulb | 4.95 | |
| Ovary | 4.1 | |
| Pancreas | 4.95 | |
| PancreaticIslet | 6.8 | |
| ParietalLobe | 6.45 | |
| Pituitary | 7.3 | |
| Placenta | 6.6 | |
| Pons | 6.1 | |
| PrefrontalCortex | 19.85 | |
| Prostate | 9.6 | |
| Salivarygland | 4.95 | |
| SkeletalMuscle | 7.2 | |
| Skin | 4.95 | |
| SmoothMuscle | 7 | |
| Spinalcord | 6.6 | |
| SubthalamicNucleus | 5.6 | |
| SuperiorCervicalGanglion | 8 | |
| TemporalLobe | 5.65 | |
| Testis | 5.4 | |
| TestisGermCell | 6.35 | |
| TestisIntersitial | 5.2 | |
| TestisLeydigCell | 6.3 | |
| TestisSeminiferousTubule | 5.35 | |
| Thalamus | 6.2 | |
| Thymus | 4.95 | |
| Thyroid | 7.65 | |
| Tongue | 6.05 | |
| Tonsil | 6.05 | |
| Trachea | 5.2 | |
| TrigeminalGanglion | 6.1 | |
| Uterus | 5.3 | |
| UterusCorpus | 5.5 | |
| WholeBlood | 6.9 | |
| Wholebrain | 5.2 | |
| colon | 6.25 | |
| pineal_day | 8.08 | |
| pineal_night | 7.64 | |
| retina | 8.1 | |
| small_intestine | 6 | |
- Probe name: A_24_P927182
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.57 ± 0.94 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.66 ± 0.35 | |
| Basal Part of Pons | 3.15 ± 0.58 | |
| Cerebellar Cortex | 4.12 ± 0.32 | |
| Cerebellar Nuclei | 3.32 ± 0.64 | |
| Claustrum | 3.68 ± 0.74 | |
| Epithalamus | 3.67 ± 0.36 | |
| Frontal Lobe | 3.17 ± 0.7 | |
| Globus Pallidus | 3.39 ± 0.7 | |
| Hypothalamus | 3.18 ± 0.62 | |
| Insula | 3.19 ± 0.68 | |
| Limbic Lobe | 3.3 ± 0.64 | |
| Mesencephalon | 3.58 ± 0.74 | |
| Myelencephalon | 3.37 ± 0.73 | |
| Occipital Lobe | 4 ± 0.69 | |
| Parietal Lobe | 3.42 ± 0.65 | |
| Pontine Tegmentum | 3.48 ± 0.72 | |
| Striatum | 3.26 ± 0.78 | |
| Subthalamus | 3.39 ± 0.78 | |
| Temporal Lobe | 3.28 ± 0.83 | |
| Thalamus | 3.51 ± 0.62 | |
| White Matter | 4.5 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pou2f1 | CB | Cerebellum | 52.68 | |
| 40.47 | | |||
| Pou2f1 | CTX | Cerebral cortex | 13.1 | |
| 9 | | |||
| Pou2f1 | HIP | Hippocampal region | 21.4 | |
| 9.47 | | |||
| Pou2f1 | HPF | Hippocampal formation | 19.18 | |
| 10.89 | | |||
| Pou2f1 | HY | Hypothalamus | 5.73 | |
| 3.25 | | |||
| Pou2f1 | LSX | Lateral septal complex | 8.29 | |
| 4.75 | | |||
| Pou2f1 | MB | Midbrain | 3.9 | |
| 3.84 | | |||
| Pou2f1 | MY | Medulla | 10.1 | |
| 8.18 | | |||
| Pou2f1 | OLF | Olfactory bulb | 39.37 | |
| 21.95 | | |||
| Pou2f1 | P | Pons | 10.87 | |
| 9.08 | | |||
| Pou2f1 | PAL | Pallidum | 3.47 | |
| 2.57 | | |||
| Pou2f1 | RHP | Retrohippocampal region | 15.13 | |
| 12 | | |||
| Pou2f1 | sAMY | Striatum-like amygdalar nuclei | 3.2 | |
| 1.88 | | |||
| Pou2f1 | STR | Striatum | 4.53 | |
| 2.66 | | |||
| Pou2f1 | STRd | Striatum dorsal region | 2.96 | |
| 1.94 | | |||
| Pou2f1 | STRv | Striatum ventral region | 8.22 | |
| 4.06 | | |||
| Pou2f1 | TH | Thalamus | 10.38 | |
| 6.42 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00078890 | 18 | 255 | 272 | TIAATPIQTLPQSQSTPK | Peptide Atlas |