AutismKB 2.0

Annotation Detail for SDK2


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Basic Information Top
Gene Symbol:SDK2 ( FLJ10832,KIAA1514 )
Gene Full Name: sidekick homolog 2 (chicken)
Band: 17q25.1
Quick LinksEntrez ID:54549; OMIM: 607217; Uniprot ID:SDK2_HUMAN; ENSEMBL ID: ENSG00000069188; HGNC ID: 19308
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal53 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain4 / 11009893
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis22 / 33044266
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220628_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts15.8
Adipocyte13.55
AdrenalCortex15.5
Adrenalgland11.3
Amygdala14.25
Appendix13.45
AtrioventricularNode14
BDCA4+_DentriticCells12.95
Bonemarrow17.05
BronchialEpithelialCells12.85
CD105+_Endothelial13.65
CD14+_Monocytes14.5
CD19+_BCells(neg._sel.)13.9
CD33+_Myeloid16.05
CD34+16.45
CD4+_Tcells14.2
CD56+_NKCells16.05
CD71+_EarlyErythroid16.4
CD8+_Tcells12.8
CardiacMyocytes16.9
Caudatenucleus14.15
Cerebellum11
CerebellumPeduncles16.1
CiliaryGanglion10.05
CingulateCortex21.8
Colorectaladenocarcinoma12.8
DorsalRootGanglion12.5
FetalThyroid13.2
Fetalbrain16.15
Fetalliver12.2
Fetallung6.85
GlobusPallidus10.3
Heart17
Hypothalamus14.6
Kidney11
Leukemia_chronicMyelogenousK-56212.3
Leukemia_promyelocytic-HL-6011.8
Leukemialymphoblastic(MOLT-4)10.8
Liver18.2
Lung14.55
Lymphnode11.95
Lymphoma_burkitts(Daudi)17.2
Lymphoma_burkitts(Raji)18.75
MedullaOblongata12.15
OccipitalLobe18.3
OlfactoryBulb10.65
Ovary11.1
Pancreas10.35
PancreaticIslet14.55
ParietalLobe14.55
Pituitary15.95
Placenta14
Pons15.05
PrefrontalCortex16.1
Prostate15.3
Salivarygland10.1
SkeletalMuscle16.6
Skin10.8
SmoothMuscle15.05
Spinalcord15.75
SubthalamicNucleus12.9
SuperiorCervicalGanglion16.15
TemporalLobe14.6
Testis11.65
TestisGermCell11
TestisIntersitial11.3
TestisLeydigCell14.3
TestisSeminiferousTubule11.7
Thalamus14.75
Thymus10.3
Thyroid15.8
Tongue14.05
Tonsil13.25
Trachea11.3
TrigeminalGanglion17.25
Uterus10.75
UterusCorpus11.95
WholeBlood11.9
Wholebrain8.95
colon12.25
pineal_day16.9
pineal_night19.68
retina16.225
small_intestine11.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P89691
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.77 ± 0.71
Basal Forebrain8.33 ± 0.21
Basal Part of Pons8.6 ± 0.25
Cerebellar Cortex7.95 ± 0.38
Cerebellar Nuclei8.62 ± 0.43
Claustrum8.82 ± 0.58
Epithalamus7.82 ± 0.46
Frontal Lobe8.4 ± 0.55
Globus Pallidus8.6 ± 0.21
Hypothalamus8.12 ± 0.53
Insula8.27 ± 0.47
Limbic Lobe8.45 ± 0.47
Mesencephalon8.38 ± 0.49
Myelencephalon8.39 ± 0.53
Occipital Lobe8.25 ± 0.5
Parietal Lobe8.39 ± 0.44
Pontine Tegmentum8.29 ± 0.5
Striatum8.57 ± 0.53
Subthalamus8.47 ± 0.08
Temporal Lobe8.32 ± 0.55
Thalamus8.44 ± 0.43
White Matter8.13 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sdk2CBCerebellum10.44
12.1
Sdk2CTXCerebral cortex63.66
55.72
Sdk2HIPHippocampal region18.87
18.87
Sdk2HPFHippocampal formation29.04
30.28
Sdk2HYHypothalamus13.45
10.75
Sdk2LSXLateral septal complex35.59
32.19
Sdk2MBMidbrain12.1
10.57
Sdk2MYMedulla15.39
15.44
Sdk2OLFOlfactory bulb29.48
23.45
Sdk2PPons16.8
16.95
Sdk2PALPallidum16.34
14.12
Sdk2RHPRetrohippocampal region45.92
45.69
Sdk2sAMYStriatum-like amygdalar nuclei28.03
21.09
Sdk2STRStriatum15.44
13.86
Sdk2STRdStriatum dorsal region10.66
11.24
Sdk2STRvStriatum ventral region15.03
10.37
Sdk2THThalamus67.71
60.36
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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