AutismKB 2.0

Annotation Detail for GNL3L


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Basic Information Top
Gene Symbol:GNL3L ( FLJ10613 )
Gene Full Name: guanine nucleotide binding protein-like 3 (nucleolar)-like
Band: Xp11.22
Quick LinksEntrez ID:54552; OMIM: NA; Uniprot ID:GNL3L_HUMAN; ENSEMBL ID: ENSG00000130119; HGNC ID: 25553
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus20 / 56401235
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult116 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor6 / 34366174
chondrosarcoma5 / 8282360
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor22 / 26384583
glioma8 / 10688374
head and neck tumor15 / 136302110
kidney tumor0 / 689590 
leukemia10 / 95842104
liver tumor6 / 9635962
lung tumor9 / 10312787
lymphoma6 / 7175583
non-neoplasia0 / 972500 
normal106 / 336030731
ovarian tumor6 / 7668278
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer13 / 102680126
retinoblastoma6 / 46356129
skin tumor11 / 12494988
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder2 / 2975767
blood10 / 12347880
bone1 / 7165513
bone marrow0 / 488010 
brain35 / 110098931
cervix6 / 48171124
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine23 / 23447298
kidney7 / 21177733
larynx1 / 2414541
liver23 / 207743110
lung13 / 33697438
lymph5 / 44270112
lymph node4 / 9161043
mammary gland14 / 15327191
mouth8 / 67052119
muscle3 / 10771527
nerve0 / 157680 
ovary7 / 10205168
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta18 / 28082564
prostate16 / 18934584
salivary gland1 / 2015549
skin15 / 21057471
spleen8 / 53952148
stomach4 / 9661941
testis6 / 33044218
thymus3 / 8113136
thyroid5 / 47473105
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205010_at
Cell line Expression level Expression bar
721_B_lymphoblasts59.7
Adipocyte11.95
AdrenalCortex16.55
Adrenalgland11.75
Amygdala11.25
Appendix18.05
AtrioventricularNode13.95
BDCA4+_DentriticCells13.6
Bonemarrow13.3
BronchialEpithelialCells10.75
CD105+_Endothelial14.35
CD14+_Monocytes13.55
CD19+_BCells(neg._sel.)12.6
CD33+_Myeloid16.65
CD34+16.9
CD4+_Tcells14.05
CD56+_NKCells15.6
CD71+_EarlyErythroid15.95
CD8+_Tcells13.5
CardiacMyocytes22.3
Caudatenucleus11.05
Cerebellum10.1
CerebellumPeduncles18.15
CiliaryGanglion13.75
CingulateCortex14.4
Colorectaladenocarcinoma12.8
DorsalRootGanglion10.15
FetalThyroid13.7
Fetalbrain11.45
Fetalliver11.05
Fetallung8.95
GlobusPallidus12.35
Heart20.35
Hypothalamus12.7
Kidney10.9
Leukemia_chronicMyelogenousK-56211
Leukemia_promyelocytic-HL-6011.15
Leukemialymphoblastic(MOLT-4)10.9
Liver17.3
Lung15.35
Lymphnode10.7
Lymphoma_burkitts(Daudi)19.8
Lymphoma_burkitts(Raji)22.05
MedullaOblongata11.85
OccipitalLobe10.75
OlfactoryBulb9.9
Ovary11
Pancreas10.3
PancreaticIslet14.25
ParietalLobe13.55
Pituitary15.8
Placenta10.7
Pons14.75
PrefrontalCortex14.35
Prostate32.25
Salivarygland11.65
SkeletalMuscle18.6
Skin11.6
SmoothMuscle13.65
Spinalcord13.15
SubthalamicNucleus11.6
SuperiorCervicalGanglion26.4
TemporalLobe11.7
Testis10.2
TestisGermCell10.8
TestisIntersitial10.75
TestisLeydigCell15.9
TestisSeminiferousTubule11.8
Thalamus14.1
Thymus10.35
Thyroid15.45
Tongue16.8
Tonsil14.6
Trachea12.45
TrigeminalGanglion21
Uterus9.4
UterusCorpus12.7
WholeBlood14.15
Wholebrain8.35
colon12.5
pineal_day15.36
pineal_night15.34
retina14.225
small_intestine12.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P69918
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.93 ± 0.24
Basal Forebrain6.85 ± 0.18
Basal Part of Pons6.61 ± 0.25
Cerebellar Cortex7.23 ± 0.17
Cerebellar Nuclei6.61 ± 0.27
Claustrum6.97 ± 0.44
Epithalamus6.82 ± 0.31
Frontal Lobe6.85 ± 0.32
Globus Pallidus6.52 ± 0.18
Hypothalamus6.59 ± 0.35
Insula6.94 ± 0.18
Limbic Lobe7.08 ± 0.31
Mesencephalon6.94 ± 0.27
Myelencephalon6.9 ± 0.32
Occipital Lobe7.26 ± 0.37
Parietal Lobe6.93 ± 0.28
Pontine Tegmentum6.9 ± 0.28
Striatum6.78 ± 0.32
Subthalamus6.7 ± 0.47
Temporal Lobe6.92 ± 0.26
Thalamus6.82 ± 0.28
White Matter7.25 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gnl3lCBCerebellum67.32
100
Gnl3lCTXCerebral cortex100
100
Gnl3lHIPHippocampal region86.96
100
Gnl3lHPFHippocampal formation96.28
100
Gnl3lHYHypothalamus100
100
Gnl3lLSXLateral septal complex100
100
Gnl3lMBMidbrain100
100
Gnl3lMYMedulla100
100
Gnl3lOLFOlfactory bulb100
100
Gnl3lPPons94.49
100
Gnl3lPALPallidum100
100
Gnl3lRHPRetrohippocampal region100
100
Gnl3lsAMYStriatum-like amygdalar nuclei100
100
Gnl3lSTRStriatum100
100
Gnl3lSTRdStriatum dorsal region96.66
87.95
Gnl3lSTRvStriatum ventral region100
100
Gnl3lTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072385 14 328 341 LADPVTPVETILQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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