AutismKB 2.0

Annotation Detail for ING3


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Basic Information Top
Gene Symbol:ING3 ( Eaf4,FLJ20089,ING2,MEAF4,p47ING3 )
Gene Full Name: inhibitor of growth family, member 3
Band: 7q31.31
Quick LinksEntrez ID:54556; OMIM: 607493; Uniprot ID:ING3_HUMAN; ENSEMBL ID: ENSG00000071243; HGNC ID: 14587
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma4 / 17475228
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal108 / 336030732
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder4 / 29757134
blood5 / 12347840
bone1 / 7165513
bone marrow4 / 4880181
brain19 / 110098917
cervix3 / 4817162
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine6 / 23447225
kidney9 / 21177742
larynx0 / 241450 
liver4 / 20774319
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland6 / 15327139
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary5 / 10205148
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta10 / 28082535
prostate7 / 18934536
salivary gland3 / 20155148
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis13 / 33044239
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205070_at
Cell line Expression level Expression bar
721_B_lymphoblasts70.6
Adipocyte6
AdrenalCortex8.35
Adrenalgland5.4
Amygdala6.35
Appendix7.2
AtrioventricularNode5.7
BDCA4+_DentriticCells52.6
Bonemarrow5.9
BronchialEpithelialCells5.45
CD105+_Endothelial43.2
CD14+_Monocytes46.55
CD19+_BCells(neg._sel.)169.45
CD33+_Myeloid105.35
CD34+74.85
CD4+_Tcells27.6
CD56+_NKCells87.75
CD71+_EarlyErythroid10.25
CD8+_Tcells34.7
CardiacMyocytes7.15
Caudatenucleus5.1
Cerebellum5.8
CerebellumPeduncles16.2
CiliaryGanglion5.45
CingulateCortex6.9
Colorectaladenocarcinoma5.6
DorsalRootGanglion5.45
FetalThyroid7.45
Fetalbrain6.2
Fetalliver5.7
Fetallung5.35
GlobusPallidus6
Heart8.7
Hypothalamus8.1
Kidney4.85
Leukemia_chronicMyelogenousK-5628
Leukemia_promyelocytic-HL-605.6
Leukemialymphoblastic(MOLT-4)8.95
Liver9.3
Lung6.05
Lymphnode6.35
Lymphoma_burkitts(Daudi)18.75
Lymphoma_burkitts(Raji)9
MedullaOblongata6.05
OccipitalLobe6.95
OlfactoryBulb5.1
Ovary4.9
Pancreas5.4
PancreaticIslet7.6
ParietalLobe6.9
Pituitary11.6
Placenta5.9
Pons7
PrefrontalCortex21.05
Prostate7.25
Salivarygland4.65
SkeletalMuscle7.4
Skin5.4
SmoothMuscle7.1
Spinalcord6.25
SubthalamicNucleus7.6
SuperiorCervicalGanglion9.5
TemporalLobe6.9
Testis5.15
TestisGermCell5.35
TestisIntersitial5.05
TestisLeydigCell5.85
TestisSeminiferousTubule5.2
Thalamus6.65
Thymus9.05
Thyroid8.95
Tongue7.3
Tonsil8.15
Trachea4.5
TrigeminalGanglion8.15
Uterus8.3
UterusCorpus6.2
WholeBlood36.55
Wholebrain5.05
colon6.2
pineal_day14.32
pineal_night10.82
retina7.425
small_intestine6.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5752_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.73 ± 0.66
Basal Forebrain6.14 ± 0.26
Basal Part of Pons6.28 ± 0.36
Cerebellar Cortex6.52 ± 0.26
Cerebellar Nuclei6.11 ± 0.44
Claustrum5.58 ± 0.81
Epithalamus6.19 ± 0.24
Frontal Lobe6.07 ± 0.39
Globus Pallidus5.59 ± 0.23
Hypothalamus6.2 ± 0.41
Insula6.29 ± 0.33
Limbic Lobe5.71 ± 0.5
Mesencephalon5.91 ± 0.39
Myelencephalon5.88 ± 0.51
Occipital Lobe5.82 ± 0.44
Parietal Lobe6.05 ± 0.47
Pontine Tegmentum5.95 ± 0.48
Striatum5.56 ± 0.37
Subthalamus5.68 ± 0.82
Temporal Lobe6.02 ± 0.38
Thalamus6.05 ± 0.45
White Matter5.46 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ing3CBCerebellum3.08
3.3
Ing3CTXCerebral cortex5.57
3.76
Ing3HIPHippocampal region5.02
4.49
Ing3HPFHippocampal formation5.88
4.72
Ing3HYHypothalamus0.9
0.66
Ing3LSXLateral septal complex0.53
0.4
Ing3MBMidbrain2.71
2.57
Ing3MYMedulla7.83
10.22
Ing3OLFOlfactory bulb10.21
7.26
Ing3PPons4.03
4.8
Ing3PALPallidum2.12
1.81
Ing3RHPRetrohippocampal region8.17
5.57
Ing3sAMYStriatum-like amygdalar nuclei0.85
0.64
Ing3STRStriatum1.69
1.38
Ing3STRdStriatum dorsal region2.3
1.95
Ing3STRvStriatum ventral region0.59
0.35
Ing3THThalamus2.62
2.11
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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