Annotation Detail for GNB1L
Basic Information Top
| Gene Symbol: | GNB1L ( DGCRK3,GY2,KIAA1645,WDR14,WDVCF ) |
|---|---|
| Gene Full Name: | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| Band: | 22q11.21 |
| Quick Links | Entrez ID:54584; OMIM: 610778; Uniprot ID:GNB1L_HUMAN; ENSEMBL ID: ENSG00000185838; HGNC ID: 4397 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.105642
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 10 / 70761 | 141 |  |
| blastocyst | 6 / 62319 | 96 | |
| fetus | 32 / 564012 | 56 | |
| neonate | 2 / 31097 | 64 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 8 / 55556 | 143 | |
| adult | 95 / 1939121 | 48 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 10 / 263845 | 37 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 11 / 95842 | 114 | |
| liver tumor | 12 / 96359 | 124 | |
| lung tumor | 10 / 103127 | 96 | |
| lymphoma | 4 / 71755 | 55 | |
| non-neoplasia | 1 / 97250 | 10 |  |
| normal | 182 / 3360307 | 54 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 13 / 125680 | 103 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 9 / 123478 | 72 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 58 / 1100989 | 52 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 16 / 215722 | 74 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 12 / 211054 | 56 | |
| heart | 6 / 89626 | 66 | |
| intestine | 9 / 234472 | 38 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 1 / 24145 | 41 | |
| liver | 17 / 207743 | 81 | |
| lung | 20 / 336974 | 59 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 4 / 67052 | 59 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 9 / 214812 | 41 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 21 / 280825 | 74 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 15 / 210574 | 71 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 12 / 330442 | 36 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 220762_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.6 | |
| Adipocyte | 5.1 | |
| AdrenalCortex | 5.7 | |
| Adrenalgland | 4.45 | |
| Amygdala | 5.5 | |
| Appendix | 5.25 | |
| AtrioventricularNode | 4.1 | |
| BDCA4+_DentriticCells | 5.9 | |
| Bonemarrow | 5.15 | |
| BronchialEpithelialCells | 5.15 | |
| CD105+_Endothelial | 5.3 | |
| CD14+_Monocytes | 5.85 | |
| CD19+_BCells(neg._sel.) | 5.7 | |
| CD33+_Myeloid | 6.9 | |
| CD34+ | 6.55 | |
| CD4+_Tcells | 5.75 | |
| CD56+_NKCells | 6.55 | |
| CD71+_EarlyErythroid | 5.35 | |
| CD8+_Tcells | 5.2 | |
| CardiacMyocytes | 7.6 | |
| Caudatenucleus | 4.7 | |
| Cerebellum | 4.25 | |
| CerebellumPeduncles | 6.05 | |
| CiliaryGanglion | 3.75 | |
| CingulateCortex | 5.45 | |
| Colorectaladenocarcinoma | 5.95 | |
| DorsalRootGanglion | 4.1 | |
| FetalThyroid | 5.1 | |
| Fetalbrain | 5.15 | |
| Fetalliver | 4.6 | |
| Fetallung | 4.3 | |
| GlobusPallidus | 3.9 | |
| Heart | 6.95 | |
| Hypothalamus | 5.7 | |
| Kidney | 4.3 | |
| Leukemia_chronicMyelogenousK-562 | 19.65 | |
| Leukemia_promyelocytic-HL-60 | 5.45 | |
| Leukemialymphoblastic(MOLT-4) | 6.25 | |
| Liver | 7.1 | |
| Lung | 5.75 | |
| Lymphnode | 4.55 | |
| Lymphoma_burkitts(Daudi) | 7.85 | |
| Lymphoma_burkitts(Raji) | 10.95 | |
| MedullaOblongata | 4.75 | |
| OccipitalLobe | 5.5 | |
| OlfactoryBulb | 4.15 | |
| Ovary | 3.55 | |
| Pancreas | 4.85 | |
| PancreaticIslet | 5.65 | |
| ParietalLobe | 5.7 | |
| Pituitary | 6.1 | |
| Placenta | 5.4 | |
| Pons | 5.75 | |
| PrefrontalCortex | 6.3 | |
| Prostate | 6.15 | |
| Salivarygland | 4.25 | |
| SkeletalMuscle | 6.5 | |
| Skin | 3.95 | |
| SmoothMuscle | 5.95 | |
| Spinalcord | 5.55 | |
| SubthalamicNucleus | 4.75 | |
| SuperiorCervicalGanglion | 6 | |
| TemporalLobe | 4.75 | |
| Testis | 4.5 | |
| TestisGermCell | 4.35 | |
| TestisIntersitial | 4.45 | |
| TestisLeydigCell | 5.2 | |
| TestisSeminiferousTubule | 4.55 | |
| Thalamus | 5.35 | |
| Thymus | 5.65 | |
| Thyroid | 6.55 | |
| Tongue | 5.2 | |
| Tonsil | 5.1 | |
| Trachea | 4.45 | |
| TrigeminalGanglion | 5.25 | |
| Uterus | 4.3 | |
| UterusCorpus | 4.75 | |
| WholeBlood | 5.65 | |
| Wholebrain | 4.65 | |
| colon | 5.3 | |
| pineal_day | 6.52 | |
| pineal_night | 6.42 | |
| retina | 6.475 | |
| small_intestine | 5.05 | |
- Probe name: CUST_9156_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.84 ± 0.71 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.6 ± 0.76 | |
| Basal Part of Pons | 3.62 ± 0.45 | |
| Cerebellar Cortex | 3.9 ± 0.54 | |
| Cerebellar Nuclei | 3.78 ± 0.49 | |
| Claustrum | 3.88 ± 0.7 | |
| Epithalamus | 3.67 ± 0.71 | |
| Frontal Lobe | 3.9 ± 0.64 | |
| Globus Pallidus | 2.98 ± 0.64 | |
| Hypothalamus | 3.5 ± 0.42 | |
| Insula | 4.15 ± 0.53 | |
| Limbic Lobe | 3.78 ± 0.64 | |
| Mesencephalon | 3.69 ± 0.72 | |
| Myelencephalon | 3.76 ± 0.69 | |
| Occipital Lobe | 3.52 ± 0.65 | |
| Parietal Lobe | 3.81 ± 0.67 | |
| Pontine Tegmentum | 3.79 ± 0.62 | |
| Striatum | 3.25 ± 0.73 | |
| Subthalamus | 3.45 ± 0.93 | |
| Temporal Lobe | 3.99 ± 0.57 | |
| Thalamus | 3.67 ± 0.69 | |
| White Matter | 3.4 ± 0.46 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gnb1l | CB | Cerebellum | 2.59 | |
| 3.1 | | |||
| Gnb1l | CTX | Cerebral cortex | 4.48 | |
| 3.72 | | |||
| Gnb1l | HIP | Hippocampal region | 1.43 | |
| 1.78 | | |||
| Gnb1l | HPF | Hippocampal formation | 1.09 | |
| 1.31 | | |||
| Gnb1l | HY | Hypothalamus | 0.2 | |
| 0.46 | | |||
| Gnb1l | LSX | Lateral septal complex | 0.31 | |
| 0.32 | | |||
| Gnb1l | MB | Midbrain | 1.15 | |
| 1.82 | | |||
| Gnb1l | MY | Medulla | 0.77 | |
| 0.91 | | |||
| Gnb1l | OLF | Olfactory bulb | 1.66 | |
| 1.97 | | |||
| Gnb1l | P | Pons | 0.57 | |
| 1.13 | | |||
| Gnb1l | PAL | Pallidum | 0.25 | |
| 0.48 | | |||
| Gnb1l | RHP | Retrohippocampal region | 0.4 | |
| 0.55 | | |||
| Gnb1l | sAMY | Striatum-like amygdalar nuclei | 0.35 | |
| 1.07 | | |||
| Gnb1l | STR | Striatum | 0.37 | |
| 0.55 | | |||
| Gnb1l | STRd | Striatum dorsal region | 0.24 | |
| 0.32 | | |||
| Gnb1l | STRv | Striatum ventral region | 0.74 | |
| 0.97 | | |||
| Gnb1l | TH | Thalamus | 0.24 | |
| 0.32 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| GNB1L_HUMAN_2 | 16 | 2 | 17 | TAPCPPPPPDPQFVLR | PRIDE |
| PAp00068999 | 19 | 247 | 265 | GTHELTNPGIAEVTIRPDR | Peptide Atlas |