AutismKB 2.0

Annotation Detail for LZTFL1


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Basic Information Top
Gene Symbol:LZTFL1 ( FLJ36386 )
Gene Full Name: leucine zipper transcription factor-like 1
Band: 3p21.31
Quick LinksEntrez ID:54585; OMIM: 606568; Uniprot ID:LZTL1_HUMAN; ENSEMBL ID: ENSG00000163818; HGNC ID: 6741
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst7 / 62319112
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal142 / 336030742
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor17 / 125191135
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow4 / 4880181
brain43 / 110098939
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver5 / 20774324
lung14 / 33697441
lymph0 / 442700 
lymph node3 / 9161032
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta9 / 28082532
prostate0 / 1893450 
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach9 / 9661993
testis51 / 330442154
thymus27 / 81131332
thyroid1 / 4747321
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218437_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.55
Adipocyte6.85
AdrenalCortex8.7
Adrenalgland6.1
Amygdala39.9
Appendix8.7
AtrioventricularNode5.6
BDCA4+_DentriticCells12.3
Bonemarrow7.05
BronchialEpithelialCells6.5
CD105+_Endothelial7.65
CD14+_Monocytes7.1
CD19+_BCells(neg._sel.)12.15
CD33+_Myeloid8.9
CD34+19.2
CD4+_Tcells8.05
CD56+_NKCells12.4
CD71+_EarlyErythroid8.85
CD8+_Tcells14.2
CardiacMyocytes9.25
Caudatenucleus9.3
Cerebellum6.1
CerebellumPeduncles8.35
CiliaryGanglion5.9
CingulateCortex16.6
Colorectaladenocarcinoma10.55
DorsalRootGanglion5.9
FetalThyroid8.75
Fetalbrain14.05
Fetalliver6.3
Fetallung17.65
GlobusPallidus5.65
Heart9.45
Hypothalamus19.3
Kidney5.65
Leukemia_chronicMyelogenousK-5626.65
Leukemia_promyelocytic-HL-606.2
Leukemialymphoblastic(MOLT-4)138
Liver9.45
Lung7.45
Lymphnode6.15
Lymphoma_burkitts(Daudi)9
Lymphoma_burkitts(Raji)10.65
MedullaOblongata17.5
OccipitalLobe22.3
OlfactoryBulb5.55
Ovary5.1
Pancreas5.75
PancreaticIslet9.35
ParietalLobe8.65
Pituitary52.3
Placenta6.55
Pons9.55
PrefrontalCortex71.85
Prostate9.25
Salivarygland6
SkeletalMuscle8.5
Skin6.1
SmoothMuscle10.45
Spinalcord11.6
SubthalamicNucleus32.55
SuperiorCervicalGanglion9.55
TemporalLobe12.35
Testis8.1
TestisGermCell44.25
TestisIntersitial11.55
TestisLeydigCell8.6
TestisSeminiferousTubule23.65
Thalamus7.4
Thymus21.3
Thyroid64.15
Tongue7.15
Tonsil6.8
Trachea6.1
TrigeminalGanglion8.8
Uterus23.95
UterusCorpus6.85
WholeBlood7.65
Wholebrain23.05
colon7.3
pineal_day30.42
pineal_night21.72
retina11.1
small_intestine6.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P41049
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.44 ± 0.29
Basal Forebrain8.43 ± 0.15
Basal Part of Pons8.4 ± 0.45
Cerebellar Cortex8.26 ± 0.24
Cerebellar Nuclei8.01 ± 0.29
Claustrum8.67 ± 0.42
Epithalamus9.74 ± 0.76
Frontal Lobe8.61 ± 0.37
Globus Pallidus7.71 ± 0.53
Hypothalamus8.81 ± 0.18
Insula8.65 ± 0.23
Limbic Lobe8.55 ± 0.45
Mesencephalon8.55 ± 0.4
Myelencephalon8.58 ± 0.46
Occipital Lobe8.81 ± 0.39
Parietal Lobe8.68 ± 0.42
Pontine Tegmentum8.47 ± 0.4
Striatum8.29 ± 0.67
Subthalamus8.35 ± 0.23
Temporal Lobe8.74 ± 0.35
Thalamus8.41 ± 0.22
White Matter7.43 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lztfl1CBCerebellum8.48
10.17
Lztfl1CTXCerebral cortex16.62
11.86
Lztfl1HIPHippocampal region11.24
9.83
Lztfl1HPFHippocampal formation9.04
7.64
Lztfl1HYHypothalamus4.81
4.63
Lztfl1LSXLateral septal complex3.46
2.5
Lztfl1MBMidbrain5.75
6.28
Lztfl1MYMedulla8.58
8.6
Lztfl1OLFOlfactory bulb10.26
8.38
Lztfl1PPons6.91
8.77
Lztfl1PALPallidum1.79
1.4
Lztfl1RHPRetrohippocampal region6.42
5.09
Lztfl1sAMYStriatum-like amygdalar nuclei7.57
5.32
Lztfl1STRStriatum1.76
1.36
Lztfl1STRdStriatum dorsal region0.72
0.73
Lztfl1STRvStriatum ventral region1.79
1.13
Lztfl1THThalamus2.01
1.92
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063941 15 205 219 AQDLSNLENTVAALK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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