Annotation Detail for ATRX
Basic Information Top
| Gene Symbol: | ATRX ( ATR2,MGC2094,MRXHF1,RAD54,RAD54L,SFM1,SHS,XH2,XNP,ZNF-HX ) |
|---|---|
| Gene Full Name: | alpha thalassemia/mental retardation syndrome X-linked |
| Band: | Xq21.1 |
| Quick Links | Entrez ID:546; OMIM: 300032; Uniprot ID:ATRX_HUMAN; ENSEMBL ID: ENSG00000085224; HGNC ID: 886 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.533526
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 12 / 70761 | 169 |  |
| blastocyst | 6 / 62319 | 96 | |
| fetus | 74 / 564012 | 131 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 2 / 55556 | 35 | |
| adult | 186 / 1939121 | 95 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 14 / 119369 | 117 | |
| germ cell tumor | 19 / 263845 | 72 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 14 / 136302 | 102 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 10 / 96359 | 103 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 316 / 3360307 | 94 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 1 / 104616 | 9 |  |
| primitive neuroectodermal tumor of the CNS | 8 / 125680 | 63 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 9 / 125191 | 71 | |
| uterine tumor | 8 / 90257 | 88 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 4 / 123478 | 32 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 4 / 48801 | 81 | |
| brain | 73 / 1100989 | 66 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 10 / 149255 | 66 | |
| ear | 5 / 16212 | 308 |  |
| embryonic tissue | 23 / 215722 | 106 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 16 / 211054 | 75 | |
| heart | 11 / 89626 | 122 | |
| intestine | 15 / 234472 | 63 | |
| kidney | 17 / 211777 | 80 | |
| larynx | 1 / 24145 | 41 | |
| liver | 31 / 207743 | 149 | |
| lung | 37 / 336974 | 109 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 13 / 91610 | 141 | |
| mammary gland | 32 / 153271 | 208 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 19 / 107715 | 176 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 22 / 214812 | 102 | |
| parathyroid | 5 / 20539 | 243 | |
| pharynx | 4 / 41328 | 96 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 19 / 280825 | 67 | |
| prostate | 10 / 189345 | 52 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 9 / 210574 | 42 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 18 / 96619 | 186 | |
| testis | 15 / 330442 | 45 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 8 / 47473 | 168 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 23 / 232878 | 98 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208860_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 52.9 | |
| Adipocyte | 57.75 | |
| AdrenalCortex | 28.95 | |
| Adrenalgland | 21.7 | |
| Amygdala | 143.65 | |
| Appendix | 24.3 | |
| AtrioventricularNode | 38.3 | |
| BDCA4+_DentriticCells | 99.4 | |
| Bonemarrow | 25.1 | |
| BronchialEpithelialCells | 22.2 | |
| CD105+_Endothelial | 26.9 | |
| CD14+_Monocytes | 45.6 | |
| CD19+_BCells(neg._sel.) | 110.95 | |
| CD33+_Myeloid | 118.1 | |
| CD34+ | 115.9 | |
| CD4+_Tcells | 179.95 | |
| CD56+_NKCells | 144.25 | |
| CD71+_EarlyErythroid | 25.4 | |
| CD8+_Tcells | 238.65 | |
| CardiacMyocytes | 47.9 | |
| Caudatenucleus | 31.95 | |
| Cerebellum | 22.15 | |
| CerebellumPeduncles | 48.3 | |
| CiliaryGanglion | 32.5 | |
| CingulateCortex | 85.8 | |
| Colorectaladenocarcinoma | 32.5 | |
| DorsalRootGanglion | 29.15 | |
| FetalThyroid | 31.8 | |
| Fetalbrain | 221 | |
| Fetalliver | 24.1 | |
| Fetallung | 31.85 | |
| GlobusPallidus | 49.75 | |
| Heart | 19.6 | |
| Hypothalamus | 47.6 | |
| Kidney | 17.75 | |
| Leukemia_chronicMyelogenousK-562 | 14.7 | |
| Leukemia_promyelocytic-HL-60 | 22.4 | |
| Leukemialymphoblastic(MOLT-4) | 63.3 | |
| Liver | 32.8 | |
| Lung | 11.85 | |
| Lymphnode | 27.9 | |
| Lymphoma_burkitts(Daudi) | 52.45 | |
| Lymphoma_burkitts(Raji) | 46.85 | |
| MedullaOblongata | 75.85 | |
| OccipitalLobe | 87.05 | |
| OlfactoryBulb | 50.1 | |
| Ovary | 33.25 | |
| Pancreas | 28.45 | |
| PancreaticIslet | 32.1 | |
| ParietalLobe | 61 | |
| Pituitary | 68.5 | |
| Placenta | 14.8 | |
| Pons | 37.25 | |
| PrefrontalCortex | 161.95 | |
| Prostate | 34.75 | |
| Salivarygland | 59.4 | |
| SkeletalMuscle | 41.35 | |
| Skin | 28.4 | |
| SmoothMuscle | 57.25 | |
| Spinalcord | 17.7 | |
| SubthalamicNucleus | 48.85 | |
| SuperiorCervicalGanglion | 42.35 | |
| TemporalLobe | 32.15 | |
| Testis | 12.45 | |
| TestisGermCell | 20.15 | |
| TestisIntersitial | 24.8 | |
| TestisLeydigCell | 27.95 | |
| TestisSeminiferousTubule | 25.3 | |
| Thalamus | 51.75 | |
| Thymus | 21.9 | |
| Thyroid | 45.5 | |
| Tongue | 34.4 | |
| Tonsil | 63.7 | |
| Trachea | 26.1 | |
| TrigeminalGanglion | 41.3 | |
| Uterus | 70.1 | |
| UterusCorpus | 30.9 | |
| WholeBlood | 45.3 | |
| Wholebrain | 17.9 | |
| colon | 28.2 | |
| pineal_day | 298.8 | |
| pineal_night | 272.54 | |
| retina | 51.975 | |
| small_intestine | 26.55 | |
- Probe name: CUST_4633_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.68 ± 0.31 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.57 ± 0.23 | |
| Basal Part of Pons | 5.6 ± 0.37 | |
| Cerebellar Cortex | 5.93 ± 0.18 | |
| Cerebellar Nuclei | 5.33 ± 0.58 | |
| Claustrum | 5.77 ± 0.5 | |
| Epithalamus | 5.52 ± 0.26 | |
| Frontal Lobe | 5.53 ± 0.44 | |
| Globus Pallidus | 5.34 ± 0.34 | |
| Hypothalamus | 5.2 ± 0.58 | |
| Insula | 5.52 ± 0.44 | |
| Limbic Lobe | 5.61 ± 0.47 | |
| Mesencephalon | 5.51 ± 0.53 | |
| Myelencephalon | 5.48 ± 0.46 | |
| Occipital Lobe | 5.6 ± 0.47 | |
| Parietal Lobe | 5.55 ± 0.46 | |
| Pontine Tegmentum | 5.54 ± 0.44 | |
| Striatum | 5.24 ± 0.37 | |
| Subthalamus | 5.05 ± 0.71 | |
| Temporal Lobe | 5.59 ± 0.41 | |
| Thalamus | 5.54 ± 0.41 | |
| White Matter | 5.33 ± 0.28 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Atrx | CB | Cerebellum | 43 | |
| 78.42 | | |||
| Atrx | CTX | Cerebral cortex | 100 | |
| 96.09 | | |||
| Atrx | HIP | Hippocampal region | 85.36 | |
| 100 | | |||
| Atrx | HPF | Hippocampal formation | 98.18 | |
| 97.11 | | |||
| Atrx | HY | Hypothalamus | 59.75 | |
| 42.47 | | |||
| Atrx | LSX | Lateral septal complex | 100 | |
| 73.46 | | |||
| Atrx | MB | Midbrain | 71.18 | |
| 62.94 | | |||
| Atrx | MY | Medulla | 77.91 | |
| 74.59 | | |||
| Atrx | OLF | Olfactory bulb | 100 | |
| 94.91 | | |||
| Atrx | P | Pons | 63.71 | |
| 61.19 | | |||
| Atrx | PAL | Pallidum | 69.86 | |
| 59.59 | | |||
| Atrx | RHP | Retrohippocampal region | 100 | |
| 92.36 | | |||
| Atrx | sAMY | Striatum-like amygdalar nuclei | 67.67 | |
| 40.28 | | |||
| Atrx | STR | Striatum | 97.46 | |
| 69.83 | | |||
| Atrx | STRd | Striatum dorsal region | 100 | |
| 72.15 | | |||
| Atrx | STRv | Striatum ventral region | 86.79 | |
| 65.54 | | |||
| Atrx | TH | Thalamus | 94.07 | |
| 72.74 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ATRX_HUMAN_2385 | 12 | 2385 | 2396 | RREAIYNDVLTK | PRIDE |
| PAp00003484 | 10 | 189 | 198 | HPSLQVLICK | Peptide Atlas |