AutismKB 2.0

Annotation Detail for FAM63B


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Basic Information Top
Gene Symbol:FAM63B ( KIAA1164 )
Gene Full Name: family with sequence similarity 63, member B
Band: 15q21.3
Quick LinksEntrez ID:54629; OMIM: NA; Uniprot ID:FA63B_HUMAN; ENSEMBL ID: ENSG00000128923; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal79 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma5 / 46356107
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain14 / 110098912
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye11 / 21105452
heart3 / 8962633
intestine0 / 2344720 
kidney9 / 21177742
larynx0 / 241450 
liver6 / 20774328
lung6 / 33697417
lymph0 / 442700 
lymph node3 / 9161032
mammary gland10 / 15327165
mouth0 / 670520 
muscle7 / 10771564
nerve1 / 1576863
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta11 / 28082539
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach3 / 9661931
testis6 / 33044218
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214691_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts7
Adipocyte5.8
AdrenalCortex6.7
Adrenalgland5.1
Amygdala9.6
Appendix7.2
AtrioventricularNode5.45
BDCA4+_DentriticCells6.5
Bonemarrow6.15
BronchialEpithelialCells5.6
CD105+_Endothelial7.1
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid7.4
CD34+7.2
CD4+_Tcells6.4
CD56+_NKCells6.7
CD71+_EarlyErythroid5.55
CD8+_Tcells5.6
CardiacMyocytes9.5
Caudatenucleus5.25
Cerebellum4.8
CerebellumPeduncles7
CiliaryGanglion4.75
CingulateCortex6.05
Colorectaladenocarcinoma5.85
DorsalRootGanglion5.05
FetalThyroid5.7
Fetalbrain5.85
Fetalliver5.2
Fetallung4.6
GlobusPallidus4.65
Heart9.05
Hypothalamus6.15
Kidney5.1
Leukemia_chronicMyelogenousK-5625.25
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.6
Liver8.25
Lung6.3
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.65
Lymphoma_burkitts(Raji)8.85
MedullaOblongata5.25
OccipitalLobe5.2
OlfactoryBulb4.6
Ovary4.15
Pancreas4.85
PancreaticIslet6.3
ParietalLobe6.4
Pituitary6.85
Placenta6.05
Pons5.7
PrefrontalCortex7.5
Prostate6.8
Salivarygland4.85
SkeletalMuscle8.1
Skin5.2
SmoothMuscle6.7
Spinalcord6.15
SubthalamicNucleus5.95
SuperiorCervicalGanglion9.1
TemporalLobe5.4
Testis4.95
TestisGermCell4.65
TestisIntersitial4.95
TestisLeydigCell5.95
TestisSeminiferousTubule5
Thalamus5.95
Thymus4.45
Thyroid7.15
Tongue6
Tonsil5.7
Trachea4.85
TrigeminalGanglion7.05
Uterus7.65
UterusCorpus5.6
WholeBlood6.35
Wholebrain4.7
colon5.9
pineal_day30.38
pineal_night34.54
retina8
small_intestine5.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1798_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.57 ± 0.26
Basal Forebrain7.72 ± 0.21
Basal Part of Pons7.27 ± 0.27
Cerebellar Cortex7.97 ± 0.16
Cerebellar Nuclei7.74 ± 0.16
Claustrum7.62 ± 0.41
Epithalamus7.98 ± 0.17
Frontal Lobe7.65 ± 0.27
Globus Pallidus7.78 ± 0.33
Hypothalamus7.86 ± 0.16
Insula7.57 ± 0.18
Limbic Lobe7.51 ± 0.27
Mesencephalon7.7 ± 0.26
Myelencephalon7.64 ± 0.27
Occipital Lobe7.64 ± 0.34
Parietal Lobe7.64 ± 0.25
Pontine Tegmentum7.71 ± 0.29
Striatum7.76 ± 0.36
Subthalamus7.94 ± 0.09
Temporal Lobe7.52 ± 0.22
Thalamus7.73 ± 0.24
White Matter8.3 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
B230380D07RikCBCerebellum36.86
47.92
B230380D07RikCTXCerebral cortex40.18
30.71
B230380D07RikHIPHippocampal region16.86
17.45
B230380D07RikHPFHippocampal formation28.77
28.91
B230380D07RikHYHypothalamus5.44
4.84
B230380D07RikLSXLateral septal complex1.56
1.07
B230380D07RikMBMidbrain12.77
12.73
B230380D07RikMYMedulla13.94
15.67
B230380D07RikOLFOlfactory bulb42.28
39.85
B230380D07RikPPons10.79
11.97
B230380D07RikPALPallidum12.85
13.84
B230380D07RikRHPRetrohippocampal region47.93
44.32
B230380D07RiksAMYStriatum-like amygdalar nuclei5.13
3.81
B230380D07RikSTRStriatum11.65
9.85
B230380D07RikSTRdStriatum dorsal region14.09
12.33
B230380D07RikSTRvStriatum ventral region10.38
8.01
B230380D07RikTHThalamus25.44
24.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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