AutismKB 2.0

Annotation Detail for CROT


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CROT ( COT )
Gene Full Name: carnitine O-octanoyltransferase
Band: 7q21.12
Quick LinksEntrez ID:54677; OMIM: 606090; Uniprot ID:OCTC_HUMAN; ENSEMBL ID: ENSG00000005469; HGNC ID: 2366
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor5 / 26384518
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal107 / 336030731
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder6 / 29757201
blood1 / 1234788
bone1 / 7165513
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus1 / 2020949
eye11 / 21105452
heart0 / 896260 
intestine7 / 23447229
kidney9 / 21177742
larynx1 / 2414541
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth5 / 6705274
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta26 / 28082592
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis2 / 3304426
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204573_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.1
Adipocyte19.9
AdrenalCortex51
Adrenalgland23.7
Amygdala54.65
Appendix63.8
AtrioventricularNode44.2
BDCA4+_DentriticCells17.05
Bonemarrow24.5
BronchialEpithelialCells20.5
CD105+_Endothelial22.9
CD14+_Monocytes27.75
CD19+_BCells(neg._sel.)22.9
CD33+_Myeloid23.8
CD34+27.8
CD4+_Tcells31.5
CD56+_NKCells26.8
CD71+_EarlyErythroid12.25
CD8+_Tcells39.85
CardiacMyocytes19.5
Caudatenucleus19.2
Cerebellum18.25
CerebellumPeduncles43.4
CiliaryGanglion35.35
CingulateCortex34.75
Colorectaladenocarcinoma18.55
DorsalRootGanglion24.75
FetalThyroid49.85
Fetalbrain36.8
Fetalliver87.1
Fetallung18.05
GlobusPallidus21.15
Heart29.95
Hypothalamus23.8
Kidney29.6
Leukemia_chronicMyelogenousK-56217.6
Leukemia_promyelocytic-HL-6021.55
Leukemialymphoblastic(MOLT-4)24.5
Liver46.35
Lung25
Lymphnode16.3
Lymphoma_burkitts(Daudi)21.55
Lymphoma_burkitts(Raji)40.55
MedullaOblongata26.4
OccipitalLobe22.4
OlfactoryBulb17
Ovary27.85
Pancreas25.55
PancreaticIslet24.9
ParietalLobe33.85
Pituitary35.4
Placenta19.7
Pons52.1
PrefrontalCortex41.05
Prostate124.85
Salivarygland23.55
SkeletalMuscle45.1
Skin48.6
SmoothMuscle27.2
Spinalcord21.45
SubthalamicNucleus30.4
SuperiorCervicalGanglion84.85
TemporalLobe26.4
Testis17.4
TestisGermCell19.5
TestisIntersitial22.1
TestisLeydigCell36.1
TestisSeminiferousTubule22.15
Thalamus24.65
Thymus25.45
Thyroid61.1
Tongue56.05
Tonsil35.9
Trachea21.2
TrigeminalGanglion52.15
Uterus38.2
UterusCorpus33.95
WholeBlood21.15
Wholebrain12.6
colon36.85
pineal_day37.3
pineal_night36.68
retina35.975
small_intestine37.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P168669
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.46 ± 0.66
Basal Forebrain4.56 ± 0.33
Basal Part of Pons4.17 ± 0.54
Cerebellar Cortex4.44 ± 0.47
Cerebellar Nuclei4.54 ± 0.48
Claustrum4.09 ± 0.73
Epithalamus4.5 ± 0.63
Frontal Lobe4.37 ± 0.54
Globus Pallidus4.82 ± 0.74
Hypothalamus4.24 ± 0.32
Insula4.48 ± 0.45
Limbic Lobe4.27 ± 0.64
Mesencephalon4.34 ± 0.62
Myelencephalon4.36 ± 0.55
Occipital Lobe4.08 ± 0.73
Parietal Lobe4.25 ± 0.59
Pontine Tegmentum4.34 ± 0.68
Striatum4.29 ± 0.61
Subthalamus3.72 ± 0.63
Temporal Lobe4.31 ± 0.53
Thalamus4.4 ± 0.56
White Matter3.84 ± 0.93
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
OCTC_HUMAN_149 12 149 160 VGNTPLDMNQFR PRIDE
PAp00095329 20 200 219 AFVFDVIHEGCLVTPPELLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved