AutismKB 2.0

Annotation Detail for MANSC1


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Basic Information Top
Gene Symbol:MANSC1 ( 9130403P13Rik,FLJ10298,LOH12CR3 )
Gene Full Name: MANSC domain containing 1
Band: 12p13.2
Quick LinksEntrez ID:54682; OMIM: NA; Uniprot ID:MANS1_HUMAN; ENSEMBL ID: ENSG00000111261; HGNC ID: 25505
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus27 / 56401247
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor34 / 263845128
glioma0 / 1068830 
head and neck tumor9 / 13630266
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal184 / 336030754
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland6 / 33197180
ascites4 / 4001599
bladder1 / 2975733
blood13 / 123478105
bone0 / 716550 
bone marrow0 / 488010 
brain67 / 110098960
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart3 / 8962633
intestine11 / 23447246
kidney19 / 21177789
larynx0 / 241450 
liver1 / 2077434
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth12 / 67052178
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate9 / 18934547
salivary gland0 / 201550 
skin3 / 21057414
spleen6 / 53952111
stomach8 / 9661982
testis26 / 33044278
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea23 / 52413438
umbilical cord0 / 136800 
uterus28 / 232878120
vascular21 / 51780405
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220945_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.35
Adipocyte7.9
AdrenalCortex10.5
Adrenalgland8.6
Amygdala21.05
Appendix23.9
AtrioventricularNode10.35
BDCA4+_DentriticCells7.15
Bonemarrow13.1
BronchialEpithelialCells7.4
CD105+_Endothelial7.85
CD14+_Monocytes9.05
CD19+_BCells(neg._sel.)8.15
CD33+_Myeloid9.3
CD34+9.35
CD4+_Tcells7.45
CD56+_NKCells8.35
CD71+_EarlyErythroid7.6
CD8+_Tcells6.8
CardiacMyocytes15.85
Caudatenucleus8.9
Cerebellum13.35
CerebellumPeduncles10.35
CiliaryGanglion18.95
CingulateCortex11.1
Colorectaladenocarcinoma7.6
DorsalRootGanglion8.15
FetalThyroid9.6
Fetalbrain8.55
Fetalliver9.7
Fetallung7.6
GlobusPallidus7.9
Heart9.8
Hypothalamus9.5
Kidney8.5
Leukemia_chronicMyelogenousK-5627.45
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6.1
Liver11.2
Lung32.05
Lymphnode7.2
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)10.75
MedullaOblongata8.9
OccipitalLobe10.55
OlfactoryBulb7.05
Ovary10.25
Pancreas19.4
PancreaticIslet9.65
ParietalLobe9.8
Pituitary15.8
Placenta13.9
Pons11.5
PrefrontalCortex12.5
Prostate65.85
Salivarygland39.35
SkeletalMuscle12.65
Skin10.9
SmoothMuscle9.9
Spinalcord8.7
SubthalamicNucleus11.8
SuperiorCervicalGanglion21.9
TemporalLobe8.4
Testis23.05
TestisGermCell13.15
TestisIntersitial7.4
TestisLeydigCell9
TestisSeminiferousTubule7.95
Thalamus9.25
Thymus6.05
Thyroid26.25
Tongue16.7
Tonsil8.1
Trachea70.45
TrigeminalGanglion16.65
Uterus39.2
UterusCorpus8.7
WholeBlood76.8
Wholebrain15.1
colon104.8
pineal_day15.6
pineal_night13.94
retina16.275
small_intestine72.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10412_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.01 ± 0.41
Basal Forebrain6.49 ± 0.17
Basal Part of Pons6.69 ± 0.21
Cerebellar Cortex6.62 ± 0.28
Cerebellar Nuclei6.77 ± 0.29
Claustrum7.15 ± 0.63
Epithalamus6.77 ± 0.33
Frontal Lobe6.78 ± 0.35
Globus Pallidus6.32 ± 0.27
Hypothalamus6.4 ± 0.24
Insula6.72 ± 0.25
Limbic Lobe7.06 ± 0.36
Mesencephalon6.81 ± 0.37
Myelencephalon6.82 ± 0.33
Occipital Lobe7.24 ± 0.43
Parietal Lobe6.96 ± 0.32
Pontine Tegmentum6.9 ± 0.41
Striatum7.07 ± 0.39
Subthalamus6.89 ± 0.25
Temporal Lobe6.8 ± 0.3
Thalamus7.01 ± 0.34
White Matter6.13 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mansc1CBCerebellum50.98
51.14
Mansc1CTXCerebral cortex50.97
50.78
Mansc1HIPHippocampal region50.41
50.38
Mansc1HPFHippocampal formation50.28
50.25
Mansc1HYHypothalamus50.01
50.03
Mansc1LSXLateral septal complex50.05
50.04
Mansc1MBMidbrain50.14
50.29
Mansc1MYMedulla50.2
50.39
Mansc1OLFOlfactory bulb50.72
51.16
Mansc1PPons50.54
50.85
Mansc1PALPallidum50.19
50.13
Mansc1RHPRetrohippocampal region50.08
50.1
Mansc1sAMYStriatum-like amygdalar nuclei50.05
50.07
Mansc1STRStriatum50.17
50.26
Mansc1STRdStriatum dorsal region50.05
50.05
Mansc1STRvStriatum ventral region50.63
50.95
Mansc1THThalamus50.17
50.21
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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