AutismKB 2.0

Annotation Detail for SLC6A20


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Basic Information Top
Gene Symbol:SLC6A20 ( MGC161475,SIT1,XT3,Xtrp3 )
Gene Full Name: solute carrier family 6 (proline IMINO transporter), member 20
Band: 3p21.31
Quick LinksEntrez ID:54716; OMIM: 605616; Uniprot ID:S6A20_HUMAN; ENSEMBL ID: ENSG00000163817; HGNC ID: 30927
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal17 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine15 / 23447263
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach4 / 9661941
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219614_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.1
AdrenalCortex5.6
Adrenalgland4.5
Amygdala5.25
Appendix8.6
AtrioventricularNode5.2
BDCA4+_DentriticCells5.45
Bonemarrow5.55
BronchialEpithelialCells5.15
CD105+_Endothelial5.25
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid6.7
CD34+7.25
CD4+_Tcells5.6
CD56+_NKCells6.25
CD71+_EarlyErythroid5.35
CD8+_Tcells4.85
CardiacMyocytes7.9
Caudatenucleus4.7
Cerebellum4.35
CerebellumPeduncles6.15
CiliaryGanglion4.35
CingulateCortex5.45
Colorectaladenocarcinoma5.15
DorsalRootGanglion5
FetalThyroid5.2
Fetalbrain5.2
Fetalliver4.75
Fetallung4.2
GlobusPallidus4.15
Heart8.55
Hypothalamus5.6
Kidney4.4
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.1
Liver7.1
Lung5.65
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.5
MedullaOblongata4.75
OccipitalLobe4.6
OlfactoryBulb6.25
Ovary5.85
Pancreas4.2
PancreaticIslet6.15
ParietalLobe5.5
Pituitary6.1
Placenta5.2
Pons5.25
PrefrontalCortex6.35
Prostate5.95
Salivarygland4.25
SkeletalMuscle6.75
Skin4.8
SmoothMuscle5.95
Spinalcord5.6
SubthalamicNucleus5.1
SuperiorCervicalGanglion19.85
TemporalLobe4.9
Testis4.5
TestisGermCell4.3
TestisIntersitial4.45
TestisLeydigCell5.3
TestisSeminiferousTubule6.75
Thalamus5.35
Thymus4.1
Thyroid6.3
Tongue5.3
Tonsil5.2
Trachea4.3
TrigeminalGanglion41.3
Uterus4.55
UterusCorpus4.85
WholeBlood5.7
Wholebrain4.3
colon5.15
pineal_day6.52
pineal_night6.34
retina38.95
small_intestine5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P371331
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.92 ± 1.05
Basal Forebrain1.37 ± 0.23
Basal Part of Pons1.07 ± 0.34
Cerebellar Cortex1.26 ± 0.67
Cerebellar Nuclei1.76 ± 0.75
Claustrum2.12 ± 0.71
Epithalamus1.17 ± 0.84
Frontal Lobe1.54 ± 0.74
Globus Pallidus1.83 ± 0.59
Hypothalamus1.49 ± 0.77
Insula1.27 ± 0.63
Limbic Lobe1.42 ± 0.7
Mesencephalon1.61 ± 0.77
Myelencephalon1.49 ± 0.68
Occipital Lobe1.22 ± 0.62
Parietal Lobe1.47 ± 0.73
Pontine Tegmentum1.58 ± 0.72
Striatum1.24 ± 0.55
Subthalamus1.67 ± 0.75
Temporal Lobe1.57 ± 0.69
Thalamus1.43 ± 0.66
White Matter1.71 ± 0.93
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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