AutismKB 2.0

Annotation Detail for MPHOSPH8


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Basic Information Top
Gene Symbol:MPHOSPH8 ( FLJ35237,HSMPP8,TWA3,mpp8 )
Gene Full Name: M-phase phosphoprotein 8
Band: 13q12.11
Quick LinksEntrez ID:54737; OMIM: 611626; Uniprot ID:MPP8_HUMAN; ENSEMBL ID: ENSG00000196199; HGNC ID: 29810
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221771_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.65
Adipocyte6.85
AdrenalCortex8.3
Adrenalgland6.2
Amygdala44.9
Appendix7.6
AtrioventricularNode5.75
BDCA4+_DentriticCells20.45
Bonemarrow7.2
BronchialEpithelialCells6.8
CD105+_Endothelial24.25
CD14+_Monocytes41.4
CD19+_BCells(neg._sel.)52.75
CD33+_Myeloid71.4
CD34+47.3
CD4+_Tcells177.85
CD56+_NKCells89
CD71+_EarlyErythroid11.15
CD8+_Tcells202.95
CardiacMyocytes9.7
Caudatenucleus16.95
Cerebellum5.65
CerebellumPeduncles9.2
CiliaryGanglion5.15
CingulateCortex9.4
Colorectaladenocarcinoma20.65
DorsalRootGanglion5.45
FetalThyroid6.75
Fetalbrain16.8
Fetalliver6.5
Fetallung6.75
GlobusPallidus9.45
Heart9.85
Hypothalamus63.1
Kidney6.1
Leukemia_chronicMyelogenousK-5626.5
Leukemia_promyelocytic-HL-606.4
Leukemialymphoblastic(MOLT-4)5.5
Liver9.45
Lung8
Lymphnode60.25
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)11
MedullaOblongata12.2
OccipitalLobe36.3
OlfactoryBulb5.55
Ovary5.15
Pancreas21
PancreaticIslet19.5
ParietalLobe16.95
Pituitary24
Placenta6.25
Pons7.45
PrefrontalCortex32.2
Prostate9.6
Salivarygland5.6
SkeletalMuscle8.6
Skin6.05
SmoothMuscle9.4
Spinalcord8.95
SubthalamicNucleus20.95
SuperiorCervicalGanglion8.5
TemporalLobe6.85
Testis6.05
TestisGermCell6.85
TestisIntersitial9.45
TestisLeydigCell7.3
TestisSeminiferousTubule6.4
Thalamus17.05
Thymus19.3
Thyroid35.15
Tongue7.2
Tonsil18.4
Trachea6.65
TrigeminalGanglion9.15
Uterus34.45
UterusCorpus6.6
WholeBlood8.45
Wholebrain11.2
colon7.2
pineal_day66.6
pineal_night66.7
retina14.225
small_intestine7.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P188183
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.87 ± 0.21
Basal Forebrain10.74 ± 0.23
Basal Part of Pons10.75 ± 0.28
Cerebellar Cortex10.46 ± 0.16
Cerebellar Nuclei10.55 ± 0.16
Claustrum11.1 ± 0.43
Epithalamus10.51 ± 0.27
Frontal Lobe10.63 ± 0.28
Globus Pallidus11.06 ± 0.19
Hypothalamus10.52 ± 0.24
Insula10.62 ± 0.18
Limbic Lobe10.89 ± 0.34
Mesencephalon10.81 ± 0.24
Myelencephalon10.71 ± 0.29
Occipital Lobe11.02 ± 0.3
Parietal Lobe10.82 ± 0.25
Pontine Tegmentum10.67 ± 0.29
Striatum10.91 ± 0.24
Subthalamus10.84 ± 0.1
Temporal Lobe10.67 ± 0.25
Thalamus10.59 ± 0.2
White Matter11.1 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4930548G07RikCBCerebellum20.69
20.87
4930548G07RikCTXCerebral cortex24.9
18.73
4930548G07RikHIPHippocampal region17.56
19
4930548G07RikHPFHippocampal formation16.04
15.32
4930548G07RikHYHypothalamus4.12
3.33
4930548G07RikLSXLateral septal complex7.69
5.4
4930548G07RikMBMidbrain11.71
10.64
4930548G07RikMYMedulla20.62
23.95
4930548G07RikOLFOlfactory bulb19.67
14.93
4930548G07RikPPons14.53
16.41
4930548G07RikPALPallidum7.24
6.57
4930548G07RikRHPRetrohippocampal region13.65
10.33
4930548G07RiksAMYStriatum-like amygdalar nuclei5.6
4.17
4930548G07RikSTRStriatum9.39
6.72
4930548G07RikSTRdStriatum dorsal region8.62
6.34
4930548G07RikSTRvStriatum ventral region15.76
10.17
4930548G07RikTHThalamus14.28
12.2
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MPP8_HUMAN_1 9 1 9 MEQVAEGAR PRIDE
MPP8_HUMAN_677 8 677 684 RGNSDIVR PRIDE
MPP8_HUMAN_848 9 848 856 VKLLIGAYR PRIDE
PAp00497446 31 257 287 FVESQVESESSVLNDSPFPEDDSEGLHSDSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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