AutismKB 2.0

Annotation Detail for GRAMD1C


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Basic Information Top
Gene Symbol:GRAMD1C ( DKFZp434C0328,DKFZp686K06117,FLJ35862,FLJ40464 )
Gene Full Name: GRAM domain containing 1C
Band: 3q13.31
Quick LinksEntrez ID:54762; OMIM: NA; Uniprot ID:GRM1C_HUMAN; ENSEMBL ID: ENSG00000178075; HGNC ID: 25252
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal82 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine3 / 23447212
kidney9 / 21177742
larynx0 / 241450 
liver8 / 20774338
lung4 / 33697411
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta8 / 28082528
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis56 / 330442169
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219313_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.2
Adipocyte8.35
AdrenalCortex11.65
Adrenalgland7.8
Amygdala9.6
Appendix44.2
AtrioventricularNode10.4
BDCA4+_DentriticCells8.35
Bonemarrow9.55
BronchialEpithelialCells8.05
CD105+_Endothelial8.45
CD14+_Monocytes9.35
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid10.2
CD34+10.15
CD4+_Tcells8.65
CD56+_NKCells9.55
CD71+_EarlyErythroid8.45
CD8+_Tcells7.5
CardiacMyocytes17.25
Caudatenucleus8
Cerebellum7.25
CerebellumPeduncles11.15
CiliaryGanglion9.15
CingulateCortex9.35
Colorectaladenocarcinoma8.65
DorsalRootGanglion9.15
FetalThyroid8.8
Fetalbrain8.25
Fetalliver7.85
Fetallung6.4
GlobusPallidus8.35
Heart14.1
Hypothalamus13.35
Kidney8.9
Leukemia_chronicMyelogenousK-5627.6
Leukemia_promyelocytic-HL-607.65
Leukemialymphoblastic(MOLT-4)6.6
Liver13.85
Lung9.35
Lymphnode7
Lymphoma_burkitts(Daudi)11.85
Lymphoma_burkitts(Raji)14.45
MedullaOblongata7.7
OccipitalLobe7.85
OlfactoryBulb6.6
Ovary6.9
Pancreas10
PancreaticIslet21.25
ParietalLobe10.2
Pituitary20.05
Placenta8.25
Pons8.9
PrefrontalCortex19.35
Prostate9.65
Salivarygland7.55
SkeletalMuscle15.05
Skin10.55
SmoothMuscle9.7
Spinalcord9.25
SubthalamicNucleus8.65
SuperiorCervicalGanglion16.65
TemporalLobe8.25
Testis9.45
TestisGermCell9.25
TestisIntersitial12.65
TestisLeydigCell13.05
TestisSeminiferousTubule7.55
Thalamus9.55
Thymus6.35
Thyroid14.55
Tongue12
Tonsil8.95
Trachea7.05
TrigeminalGanglion11.5
Uterus6.65
UterusCorpus9.4
WholeBlood9.35
Wholebrain6.7
colon8.65
pineal_day10.56
pineal_night10.12
retina10.35
small_intestine8.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P915095
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.35 ± 0.7
Basal Forebrain7.14 ± 0.5
Basal Part of Pons6.39 ± 0.91
Cerebellar Cortex6.12 ± 0.3
Cerebellar Nuclei6.33 ± 0.72
Claustrum7.59 ± 0.77
Epithalamus6.95 ± 0.64
Frontal Lobe6.64 ± 0.64
Globus Pallidus8.47 ± 0.65
Hypothalamus6.58 ± 0.52
Insula6.68 ± 0.56
Limbic Lobe7.03 ± 0.89
Mesencephalon7.14 ± 0.66
Myelencephalon6.97 ± 0.81
Occipital Lobe7.34 ± 0.7
Parietal Lobe6.92 ± 0.75
Pontine Tegmentum7.06 ± 0.58
Striatum7.48 ± 0.69
Subthalamus7.31 ± 0.62
Temporal Lobe6.73 ± 0.72
Thalamus6.96 ± 0.54
White Matter6.59 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gramd1cCBCerebellum3.72
4.18
Gramd1cCTXCerebral cortex3.33
2.83
Gramd1cHIPHippocampal region5.21
5.03
Gramd1cHPFHippocampal formation3.94
3.53
Gramd1cHYHypothalamus1.01
1.22
Gramd1cLSXLateral septal complex0.12
0.2
Gramd1cMBMidbrain1.43
1.58
Gramd1cMYMedulla4.6
4.64
Gramd1cOLFOlfactory bulb7.1
6.76
Gramd1cPPons3.67
4.09
Gramd1cPALPallidum1.9
1.8
Gramd1cRHPRetrohippocampal region2.2
1.76
Gramd1csAMYStriatum-like amygdalar nuclei0.86
0.5
Gramd1cSTRStriatum1.61
1.17
Gramd1cSTRdStriatum dorsal region1.14
0.81
Gramd1cSTRvStriatum ventral region4.24
2.94
Gramd1cTHThalamus1.5
1.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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