AutismKB 2.0

Annotation Detail for RNF111


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Basic Information Top
Gene Symbol:RNF111 ( ARK,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,FLJ38008 )
Gene Full Name: ring finger protein 111
Band: 15q22.1-q22.2
Quick LinksEntrez ID:54778; OMIM: 605840; Uniprot ID:RN111_HUMAN; ENSEMBL ID: ENSG00000157450; HGNC ID: 17384
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst1 / 6231916
fetus29 / 56401251
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma3 / 10688328
head and neck tumor11 / 13630280
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor24 / 96359249
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal114 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone4 / 7165555
bone marrow1 / 4880120
brain36 / 110098932
cervix3 / 4817162
connective tissue1 / 1492556
ear4 / 16212246
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye3 / 21105414
heart4 / 8962644
intestine2 / 2344728
kidney4 / 21177718
larynx3 / 24145124
liver26 / 207743125
lung5 / 33697414
lymph0 / 442700 
lymph node9 / 9161098
mammary gland5 / 15327132
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis19 / 33044257
thymus2 / 8113124
thyroid6 / 47473126
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218761_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.25
Adipocyte9.9
AdrenalCortex9.45
Adrenalgland9.1
Amygdala24.4
Appendix12.35
AtrioventricularNode8.35
BDCA4+_DentriticCells29.3
Bonemarrow11.2
BronchialEpithelialCells20.85
CD105+_Endothelial10.55
CD14+_Monocytes48.1
CD19+_BCells(neg._sel.)32.1
CD33+_Myeloid64.4
CD34+27.3
CD4+_Tcells45
CD56+_NKCells29.15
CD71+_EarlyErythroid4.65
CD8+_Tcells47.8
CardiacMyocytes13.5
Caudatenucleus13.2
Cerebellum21.45
CerebellumPeduncles25.35
CiliaryGanglion7.5
CingulateCortex11.15
Colorectaladenocarcinoma8.05
DorsalRootGanglion8.05
FetalThyroid11.55
Fetalbrain43.8
Fetalliver10.3
Fetallung15.25
GlobusPallidus9.4
Heart13.05
Hypothalamus31.8
Kidney8.95
Leukemia_chronicMyelogenousK-56214.3
Leukemia_promyelocytic-HL-6012.75
Leukemialymphoblastic(MOLT-4)12.55
Liver12.85
Lung11.85
Lymphnode25.55
Lymphoma_burkitts(Daudi)22.1
Lymphoma_burkitts(Raji)13.8
MedullaOblongata15.2
OccipitalLobe20.5
OlfactoryBulb13.65
Ovary6.4
Pancreas6.65
PancreaticIslet15.55
ParietalLobe12.8
Pituitary32.05
Placenta28.4
Pons9.45
PrefrontalCortex29.1
Prostate12.05
Salivarygland14.7
SkeletalMuscle12.5
Skin8.15
SmoothMuscle21.1
Spinalcord18.85
SubthalamicNucleus13.1
SuperiorCervicalGanglion12
TemporalLobe8.65
Testis8.55
TestisGermCell8.65
TestisIntersitial5.3
TestisLeydigCell9.15
TestisSeminiferousTubule6.2
Thalamus11.95
Thymus11.5
Thyroid24.7
Tongue9.35
Tonsil12.55
Trachea10.05
TrigeminalGanglion10.15
Uterus20.15
UterusCorpus9
WholeBlood132.2
Wholebrain38.5
colon9.15
pineal_day43.36
pineal_night63.38
retina19.4
small_intestine8.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6716_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.03 ± 0.44
Basal Forebrain4.32 ± 0.4
Basal Part of Pons4.86 ± 0.26
Cerebellar Cortex4.93 ± 0.31
Cerebellar Nuclei4.57 ± 0.3
Claustrum4.64 ± 0.68
Epithalamus4.27 ± 0.81
Frontal Lobe4.54 ± 0.55
Globus Pallidus4.2 ± 0.52
Hypothalamus4.92 ± 0.38
Insula4.79 ± 0.31
Limbic Lobe4.63 ± 0.44
Mesencephalon4.55 ± 0.48
Myelencephalon4.55 ± 0.52
Occipital Lobe4.83 ± 0.35
Parietal Lobe4.64 ± 0.5
Pontine Tegmentum4.51 ± 0.52
Striatum4.4 ± 0.42
Subthalamus4.5 ± 0.46
Temporal Lobe4.57 ± 0.46
Thalamus4.47 ± 0.48
White Matter4.92 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnf111CBCerebellum0.4
1.01
Rnf111CTXCerebral cortex0.29
0.49
Rnf111HIPHippocampal region0.19
0.24
Rnf111HPFHippocampal formation0.14
0.16
Rnf111HYHypothalamus0.24
0.22
Rnf111LSXLateral septal complex0.08
0.06
Rnf111MBMidbrain0.32
0.62
Rnf111MYMedulla0.33
0.53
Rnf111OLFOlfactory bulb0.21
0.17
Rnf111PPons1.43
2.11
Rnf111PALPallidum0.14
0.22
Rnf111RHPRetrohippocampal region0.05
0.03
Rnf111sAMYStriatum-like amygdalar nuclei0.55
1.22
Rnf111STRStriatum0.26
0.61
Rnf111STRdStriatum dorsal region0.19
0.31
Rnf111STRvStriatum ventral region0.45
1.56
Rnf111THThalamus0.27
0.48
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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