AutismKB 2.0

Annotation Detail for TET2


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Basic Information Top
Gene Symbol:TET2 ( FLJ20032,KIAA1546,MGC125715 )
Gene Full Name: tet oncogene family member 2
Band: 4q24
Quick LinksEntrez ID:54790; OMIM: 612839; Uniprot ID:TET2_HUMAN; ENSEMBL ID: ENSG00000168769; HGNC ID: 25941
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult172 / 193912188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor101 / 941781072
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor16 / 136302117
kidney tumor0 / 689590 
leukemia26 / 95842271
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood29 / 123478234
bone1 / 7165513
bone marrow2 / 4880140
brain19 / 110098917
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph1 / 4427022
lymph node3 / 9161032
mammary gland105 / 153271685
mouth16 / 67052238
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13544_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.36 ± 0.54
Basal Forebrain4.52 ± 0.37
Basal Part of Pons3.91 ± 0.55
Cerebellar Cortex4.24 ± 0.37
Cerebellar Nuclei4.43 ± 0.62
Claustrum3.94 ± 0.81
Epithalamus5.13 ± 0.68
Frontal Lobe4.17 ± 0.49
Globus Pallidus5.21 ± 0.46
Hypothalamus4.33 ± 0.58
Insula4.08 ± 0.26
Limbic Lobe4.12 ± 0.48
Mesencephalon4.42 ± 0.54
Myelencephalon4.3 ± 0.57
Occipital Lobe4.69 ± 0.55
Parietal Lobe4.27 ± 0.48
Pontine Tegmentum4.36 ± 0.48
Striatum4.65 ± 0.41
Subthalamus3.84 ± 0.5
Temporal Lobe4.25 ± 0.47
Thalamus4.45 ± 0.44
White Matter5.96 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
E130014J05RikCBCerebellum20.56
24.28
E130014J05RikCTXCerebral cortex64.9
47.57
E130014J05RikHIPHippocampal region42.01
47.75
E130014J05RikHPFHippocampal formation49.22
48.16
E130014J05RikHYHypothalamus28.67
20.22
E130014J05RikLSXLateral septal complex60.13
45
E130014J05RikMBMidbrain33.28
28.13
E130014J05RikMYMedulla31.1
30.23
E130014J05RikOLFOlfactory bulb53.13
40.21
E130014J05RikPPons22.97
21.51
E130014J05RikPALPallidum28.08
21.75
E130014J05RikRHPRetrohippocampal region60.89
49.4
E130014J05RiksAMYStriatum-like amygdalar nuclei45.5
30.8
E130014J05RikSTRStriatum49.51
36.09
E130014J05RikSTRdStriatum dorsal region44.05
31.94
E130014J05RikSTRvStriatum ventral region68.69
51.22
E130014J05RikTHThalamus49.2
37.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018