AutismKB 2.0

Annotation Detail for PPIC


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Basic Information Top
Gene Symbol:PPIC ( CYPC,MGC3673 )
Gene Full Name: peptidylprolyl isomerase C (cyclophilin C)
Band: 5q23.2
Quick LinksEntrez ID:5480; OMIM: 123842; Uniprot ID:PPIC_HUMAN; ENSEMBL ID: ENSG00000168938; HGNC ID: 9256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst0 / 623190 
fetus11 / 56401219
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma12 / 82823144
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal81 / 336030724
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone8 / 71655111
bone marrow0 / 488010 
brain4 / 11009893
cervix3 / 4817162
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye4 / 21105418
heart1 / 8962611
intestine2 / 2344728
kidney5 / 21177723
larynx3 / 24145124
liver0 / 2077430 
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary6 / 10205158
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate2 / 18934510
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach8 / 9661982
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord1 / 1368073
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204518_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.7
Adipocyte102.85
AdrenalCortex13.95
Adrenalgland15.35
Amygdala8.6
Appendix9.4
AtrioventricularNode11.6
BDCA4+_DentriticCells8.75
Bonemarrow9.35
BronchialEpithelialCells52.15
CD105+_Endothelial8.2
CD14+_Monocytes7.85
CD19+_BCells(neg._sel.)9.9
CD33+_Myeloid9.55
CD34+10.3
CD4+_Tcells9.3
CD56+_NKCells9.85
CD71+_EarlyErythroid8.1
CD8+_Tcells8
CardiacMyocytes94.5
Caudatenucleus8.15
Cerebellum7.55
CerebellumPeduncles12.75
CiliaryGanglion11.6
CingulateCortex9.95
Colorectaladenocarcinoma41.65
DorsalRootGanglion8.3
FetalThyroid30.7
Fetalbrain8.25
Fetalliver15.5
Fetallung60.85
GlobusPallidus6.65
Heart39.25
Hypothalamus9.7
Kidney14.8
Leukemia_chronicMyelogenousK-56225.75
Leukemia_promyelocytic-HL-608.25
Leukemialymphoblastic(MOLT-4)7.1
Liver17.05
Lung57.6
Lymphnode9.35
Lymphoma_burkitts(Daudi)12.1
Lymphoma_burkitts(Raji)12.75
MedullaOblongata7.65
OccipitalLobe8
OlfactoryBulb9.8
Ovary11.8
Pancreas99
PancreaticIslet95.15
ParietalLobe9.8
Pituitary14.5
Placenta39.9
Pons9.1
PrefrontalCortex11
Prostate49.4
Salivarygland15.55
SkeletalMuscle14.8
Skin12.4
SmoothMuscle146.55
Spinalcord10
SubthalamicNucleus8.25
SuperiorCervicalGanglion11.75
TemporalLobe8.5
Testis8.05
TestisGermCell11.2
TestisIntersitial7.85
TestisLeydigCell9.45
TestisSeminiferousTubule9.1
Thalamus9.1
Thymus7.1
Thyroid169.2
Tongue20.7
Tonsil13.7
Trachea35.8
TrigeminalGanglion9.95
Uterus45.15
UterusCorpus8.45
WholeBlood9.65
Wholebrain7.5
colon135.75
pineal_day29.92
pineal_night19.16
retina11.325
small_intestine67.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P422724
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.01 ± 0.56
Basal Forebrain5.54 ± 0.29
Basal Part of Pons4.93 ± 0.4
Cerebellar Cortex5.09 ± 0.25
Cerebellar Nuclei6.46 ± 0.43
Claustrum4.89 ± 0.46
Epithalamus6.72 ± 0.53
Frontal Lobe5.56 ± 0.53
Globus Pallidus6.95 ± 0.49
Hypothalamus5.49 ± 0.51
Insula5.36 ± 0.27
Limbic Lobe5.35 ± 0.5
Mesencephalon5.83 ± 0.43
Myelencephalon5.7 ± 0.5
Occipital Lobe5.99 ± 0.62
Parietal Lobe5.63 ± 0.46
Pontine Tegmentum5.84 ± 0.48
Striatum6.3 ± 0.45
Subthalamus5.77 ± 0.24
Temporal Lobe5.38 ± 0.44
Thalamus5.92 ± 0.41
White Matter5.52 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PpicCBCerebellum100
100
PpicCTXCerebral cortex100
100
PpicHIPHippocampal region100
100
PpicHPFHippocampal formation100
100
PpicHYHypothalamus100
100
PpicLSXLateral septal complex100
100
PpicMBMidbrain100
100
PpicMYMedulla94.71
95.86
PpicOLFOlfactory bulb100
100
PpicPPons84.06
80.41
PpicPALPallidum97.49
95.94
PpicRHPRetrohippocampal region100
100
PpicsAMYStriatum-like amygdalar nuclei100
100
PpicSTRStriatum100
100
PpicSTRdStriatum dorsal region100
100
PpicSTRvStriatum ventral region100
100
PpicTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00443259 13 66 78 TVENFVALATGEK Peptide Atlas
PPIC_HUMAN_202 10 202 211 TPFVVEIADW PRIDE
PPIC_HUMAN_65 13 65 77 TVENFVALATGEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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