AutismKB 2.0

Annotation Detail for ZNF280D


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF280D ( MGC21637,MGC61687,SUHW4,ZNF634 )
Gene Full Name: zinc finger protein 280D
Band: 15q21.2
Quick LinksEntrez ID:54816; OMIM: NA; Uniprot ID:Z280D_HUMAN; ENSEMBL ID: ENSG00000137871; HGNC ID: 25953
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus28 / 56401249
neonate3 / 3109796
infant1 / 2362042
juvenile0 / 555560 
adult61 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia7 / 9725071
normal131 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone1 / 7165513
bone marrow3 / 4880161
brain56 / 110098950
cervix1 / 4817120
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine6 / 23447225
kidney4 / 21177718
larynx2 / 2414582
liver4 / 20774319
lung10 / 33697429
lymph0 / 442700 
lymph node4 / 9161043
mammary gland6 / 15327139
mouth2 / 6705229
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate1 / 1893455
salivary gland1 / 2015549
skin5 / 21057423
spleen0 / 539520 
stomach4 / 9661941
testis6 / 33044218
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221213_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.5
Adipocyte7.8
AdrenalCortex13.15
Adrenalgland7.5
Amygdala9.3
Appendix13.65
AtrioventricularNode12.6
BDCA4+_DentriticCells9.9
Bonemarrow9.95
BronchialEpithelialCells7.55
CD105+_Endothelial17
CD14+_Monocytes9.4
CD19+_BCells(neg._sel.)17.5
CD33+_Myeloid13.95
CD34+12.9
CD4+_Tcells12.95
CD56+_NKCells11.15
CD71+_EarlyErythroid8.2
CD8+_Tcells8.2
CardiacMyocytes18.2
Caudatenucleus7.55
Cerebellum6.5
CerebellumPeduncles11.85
CiliaryGanglion12.1
CingulateCortex9.35
Colorectaladenocarcinoma7.6
DorsalRootGanglion9.6
FetalThyroid8.85
Fetalbrain25.05
Fetalliver7.5
Fetallung6.2
GlobusPallidus8.6
Heart15.95
Hypothalamus10.9
Kidney7.85
Leukemia_chronicMyelogenousK-5627.35
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6.5
Liver14.45
Lung8.4
Lymphnode9.55
Lymphoma_burkitts(Daudi)11.25
Lymphoma_burkitts(Raji)14.3
MedullaOblongata8.75
OccipitalLobe7.7
OlfactoryBulb6.35
Ovary7.65
Pancreas7.4
PancreaticIslet9.75
ParietalLobe10.85
Pituitary12.85
Placenta7.35
Pons8.95
PrefrontalCortex26.55
Prostate8.75
Salivarygland7.25
SkeletalMuscle13.9
Skin10.4
SmoothMuscle9.15
Spinalcord15.75
SubthalamicNucleus10.1
SuperiorCervicalGanglion14.75
TemporalLobe8.1
Testis6.6
TestisGermCell6.3
TestisIntersitial7.95
TestisLeydigCell8.95
TestisSeminiferousTubule6.9
Thalamus9.35
Thymus5.65
Thyroid27.1
Tongue10.5
Tonsil8.3
Trachea6.85
TrigeminalGanglion17
Uterus34.5
UterusCorpus8.7
WholeBlood9.25
Wholebrain6.35
colon7.55
pineal_day73.94
pineal_night43.66
retina10
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_722_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.64 ± 0.31
Basal Forebrain7.55 ± 0.23
Basal Part of Pons7.63 ± 0.17
Cerebellar Cortex7.92 ± 0.16
Cerebellar Nuclei7.46 ± 0.22
Claustrum7.65 ± 0.27
Epithalamus7.9 ± 0.32
Frontal Lobe7.52 ± 0.27
Globus Pallidus7.56 ± 0.26
Hypothalamus7.48 ± 0.22
Insula7.55 ± 0.22
Limbic Lobe7.64 ± 0.31
Mesencephalon7.6 ± 0.28
Myelencephalon7.58 ± 0.28
Occipital Lobe7.97 ± 0.28
Parietal Lobe7.67 ± 0.26
Pontine Tegmentum7.61 ± 0.32
Striatum7.45 ± 0.24
Subthalamus7.5 ± 0.19
Temporal Lobe7.52 ± 0.28
Thalamus7.64 ± 0.21
White Matter8.34 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Suhw4CBCerebellum3.9
4.91
Suhw4CTXCerebral cortex35.68
28.21
Suhw4HIPHippocampal region27.95
33.34
Suhw4HPFHippocampal formation22.18
23.36
Suhw4HYHypothalamus15.7
11.01
Suhw4LSXLateral septal complex19.32
13.12
Suhw4MBMidbrain8.65
8.73
Suhw4MYMedulla5.1
6.9
Suhw4OLFOlfactory bulb21.07
17.06
Suhw4PPons7.84
9.09
Suhw4PALPallidum11.84
9.18
Suhw4RHPRetrohippocampal region12.94
10.43
Suhw4sAMYStriatum-like amygdalar nuclei4.15
2.68
Suhw4STRStriatum14.06
10.18
Suhw4STRdStriatum dorsal region11.19
8.6
Suhw4STRvStriatum ventral region25.58
16.61
Suhw4THThalamus24.7
23.42
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved