AutismKB 2.0

Annotation Detail for TRPM7


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Basic Information Top
Gene Symbol:TRPM7 ( CHAK,CHAK1,FLJ20117,FLJ25718,LTRPC7,TRP-PLIK )
Gene Full Name: transient receptor potential cation channel, subfamily M, member 7
Band: 15q21.2
Quick LinksEntrez ID:54822; OMIM: 605692; Uniprot ID:TRPM7_HUMAN; ENSEMBL ID: ENSG00000092439; HGNC ID: 17994
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor1 / 1142468
esophageal tumor7 / 17290404
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma8 / 10688374
head and neck tumor8 / 13630258
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal92 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone2 / 7165527
bone marrow7 / 48801143
brain22 / 110098919
cervix2 / 4817141
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue9 / 21572241
esophagus7 / 20209346
eye4 / 21105418
heart1 / 8962611
intestine7 / 23447229
kidney6 / 21177728
larynx0 / 241450 
liver10 / 20774348
lung5 / 33697414
lymph0 / 442700 
lymph node12 / 91610130
mammary gland12 / 15327178
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid3 / 20539146
pharynx6 / 41328145
pituitary gland3 / 16585180
placenta6 / 28082521
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach2 / 9661920
testis8 / 33044224
thymus2 / 8113124
thyroid5 / 47473105
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus9 / 23287838
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P50829
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.8 ± 0.27
Basal Forebrain7.9 ± 0.07
Basal Part of Pons7.72 ± 0.2
Cerebellar Cortex8.17 ± 0.15
Cerebellar Nuclei7.94 ± 0.24
Claustrum8.24 ± 0.32
Epithalamus8.04 ± 0.14
Frontal Lobe7.8 ± 0.24
Globus Pallidus7.94 ± 0.25
Hypothalamus7.66 ± 0.16
Insula7.82 ± 0.18
Limbic Lobe7.91 ± 0.33
Mesencephalon7.95 ± 0.29
Myelencephalon7.85 ± 0.27
Occipital Lobe8.23 ± 0.33
Parietal Lobe7.89 ± 0.24
Pontine Tegmentum7.89 ± 0.29
Striatum7.98 ± 0.33
Subthalamus7.94 ± 0.13
Temporal Lobe7.78 ± 0.25
Thalamus7.77 ± 0.19
White Matter8.71 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trpm7CBCerebellum21.36
20.69
Trpm7CTXCerebral cortex66.79
45.48
Trpm7HIPHippocampal region40.84
49.3
Trpm7HPFHippocampal formation44.01
42.66
Trpm7HYHypothalamus32.47
22.72
Trpm7LSXLateral septal complex37.5
24.24
Trpm7MBMidbrain38.34
30.26
Trpm7MYMedulla35.82
33.32
Trpm7OLFOlfactory bulb68.86
49.82
Trpm7PPons35.98
30.13
Trpm7PALPallidum33.7
25.5
Trpm7RHPRetrohippocampal region50.37
34.28
Trpm7sAMYStriatum-like amygdalar nuclei40.37
24.28
Trpm7STRStriatum36.33
23.04
Trpm7STRdStriatum dorsal region34.14
22.16
Trpm7STRvStriatum ventral region44.17
26.33
Trpm7THThalamus34.26
26.08
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003555 23 83 105 HTEQSPTDAYGVINFQGGSHSYR Peptide Atlas
TRPM7_HUMAN_351 23 351 373 KTFNFGQNEALHLFQTLMECMKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018