AutismKB 2.0

Annotation Detail for MFSD6


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Basic Information Top
Gene Symbol:MFSD6 ( FLJ20160,MMR2,hMMR2 )
Gene Full Name: major facilitator superfamily domain containing 6
Band: 2q32.2
Quick LinksEntrez ID:54842; OMIM: 613476; Uniprot ID:MFSD6_HUMAN; ENSEMBL ID: ENSG00000151690; HGNC ID: 24711
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor3 / 26384511
glioma4 / 10688337
head and neck tumor18 / 136302132
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal118 / 336030735
ovarian tumor15 / 76682195
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain37 / 110098933
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart7 / 8962678
intestine17 / 23447272
kidney2 / 2117779
larynx3 / 24145124
liver1 / 2077434
lung30 / 33697489
lymph1 / 4427022
lymph node7 / 9161076
mammary gland7 / 15327145
mouth9 / 67052134
muscle2 / 10771518
nerve3 / 15768190
ovary15 / 102051146
pancreas7 / 21481232
parathyroid4 / 20539194
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta7 / 28082524
prostate2 / 18934510
salivary gland1 / 2015549
skin4 / 21057418
spleen2 / 5395237
stomach4 / 9661941
testis11 / 33044233
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219858_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.85
Adipocyte10.65
AdrenalCortex18.7
Adrenalgland11.1
Amygdala23.8
Appendix27.7
AtrioventricularNode15.2
BDCA4+_DentriticCells11.4
Bonemarrow14
BronchialEpithelialCells11.7
CD105+_Endothelial11.8
CD14+_Monocytes13.5
CD19+_BCells(neg._sel.)11.95
CD33+_Myeloid14.35
CD34+13.5
CD4+_Tcells10.75
CD56+_NKCells11.3
CD71+_EarlyErythroid11.8
CD8+_Tcells9.85
CardiacMyocytes30.6
Caudatenucleus11.1
Cerebellum9.7
CerebellumPeduncles15.15
CiliaryGanglion13.35
CingulateCortex14.95
Colorectaladenocarcinoma11.95
DorsalRootGanglion14.6
FetalThyroid13.3
Fetalbrain10.65
Fetalliver10.75
Fetallung7.45
GlobusPallidus11.45
Heart26.8
Hypothalamus11.75
Kidney11.7
Leukemia_chronicMyelogenousK-5629.9
Leukemia_promyelocytic-HL-609.85
Leukemialymphoblastic(MOLT-4)8.35
Liver19.6
Lung12.3
Lymphnode9.7
Lymphoma_burkitts(Daudi)16.25
Lymphoma_burkitts(Raji)20
MedullaOblongata10.9
OccipitalLobe12.65
OlfactoryBulb9.25
Ovary9.95
Pancreas11.4
PancreaticIslet13.5
ParietalLobe15.2
Pituitary15.85
Placenta10.1
Pons12.6
PrefrontalCortex13.2
Prostate12.6
Salivarygland10.8
SkeletalMuscle24.1
Skin12
SmoothMuscle13.15
Spinalcord11.85
SubthalamicNucleus13.15
SuperiorCervicalGanglion27.85
TemporalLobe11.7
Testis9.65
TestisGermCell9
TestisIntersitial10.75
TestisLeydigCell13
TestisSeminiferousTubule9.9
Thalamus13.05
Thymus8.5
Thyroid15.05
Tongue14.35
Tonsil12.15
Trachea10.05
TrigeminalGanglion23.75
Uterus9.45
UterusCorpus13.05
WholeBlood11.6
Wholebrain10.95
colon14.55
pineal_day14.58
pineal_night17.54
retina14.5
small_intestine10.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8603_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.48 ± 0.32
Basal Forebrain7.2 ± 0.25
Basal Part of Pons7.8 ± 0.27
Cerebellar Cortex7.2 ± 0.32
Cerebellar Nuclei7.8 ± 0.27
Claustrum7.82 ± 0.64
Epithalamus6.63 ± 0.57
Frontal Lobe7.31 ± 0.36
Globus Pallidus7.71 ± 0.29
Hypothalamus7.08 ± 0.38
Insula7.15 ± 0.2
Limbic Lobe7.62 ± 0.41
Mesencephalon7.53 ± 0.51
Myelencephalon7.4 ± 0.39
Occipital Lobe7.72 ± 0.42
Parietal Lobe7.43 ± 0.35
Pontine Tegmentum7.3 ± 0.31
Striatum6.9 ± 0.47
Subthalamus7.23 ± 0.41
Temporal Lobe7.39 ± 0.29
Thalamus7.59 ± 0.29
White Matter8.19 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
2210010L05RikCBCerebellum37.96
47.9
2210010L05RikCTXCerebral cortex100
93.1
2210010L05RikHIPHippocampal region57.23
89.87
2210010L05RikHPFHippocampal formation96.12
100
2210010L05RikHYHypothalamus100
77.28
2210010L05RikLSXLateral septal complex97.31
54.36
2210010L05RikMBMidbrain93.68
76.25
2210010L05RikMYMedulla100
100
2210010L05RikOLFOlfactory bulb100
92.88
2210010L05RikPPons100
100
2210010L05RikPALPallidum76.25
57.72
2210010L05RikRHPRetrohippocampal region100
100
2210010L05RiksAMYStriatum-like amygdalar nuclei100
57.66
2210010L05RikSTRStriatum53.7
29.44
2210010L05RikSTRdStriatum dorsal region38.81
20.81
2210010L05RikSTRvStriatum ventral region59.94
32.47
2210010L05RikTHThalamus86.16
55.04
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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