AutismKB 2.0

Annotation Detail for SYTL2


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Basic Information Top
Gene Symbol:SYTL2 ( CHR11SYT,EXO4,FLJ21219,FLJ34802,FLJ42764,FLJ45597,KIAA1597,MGC102768,SGA72M,SLP2,SLP2A )
Gene Full Name: synaptotagmin-like 2
Band: 11q14.1
Quick LinksEntrez ID:54843; OMIM: 612880; Uniprot ID:SYTL2_HUMAN; ENSEMBL ID: ENSG00000137501; HGNC ID: 15585
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus19 / 56401233
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor11 / 26384541
glioma7 / 10688365
head and neck tumor4 / 13630229
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal167 / 336030749
ovarian tumor6 / 7668278
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites4 / 4001599
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain75 / 110098968
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye1 / 2110544
heart3 / 8962633
intestine20 / 23447285
kidney21 / 21177799
larynx0 / 241450 
liver3 / 20774314
lung14 / 33697441
lymph0 / 442700 
lymph node5 / 9161054
mammary gland19 / 153271123
mouth4 / 6705259
muscle7 / 10771564
nerve1 / 1576863
ovary6 / 10205158
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate6 / 18934531
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach7 / 9661972
testis10 / 33044230
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord1 / 1368073
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220613_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.95
Adipocyte7.45
AdrenalCortex9.3
Adrenalgland6.9
Amygdala7.9
Appendix10.05
AtrioventricularNode8.25
BDCA4+_DentriticCells7.25
Bonemarrow8.45
BronchialEpithelialCells7.1
CD105+_Endothelial7.75
CD14+_Monocytes8.1
CD19+_BCells(neg._sel.)8.3
CD33+_Myeloid9.45
CD34+9.7
CD4+_Tcells8.65
CD56+_NKCells9.25
CD71+_EarlyErythroid7.25
CD8+_Tcells8.9
CardiacMyocytes12.45
Caudatenucleus6.85
Cerebellum6.35
CerebellumPeduncles9.25
CiliaryGanglion9.75
CingulateCortex8.1
Colorectaladenocarcinoma7.5
DorsalRootGanglion7.15
FetalThyroid7.55
Fetalbrain7.7
Fetalliver6.9
Fetallung5.75
GlobusPallidus6.2
Heart13.35
Hypothalamus7.95
Kidney7.1
Leukemia_chronicMyelogenousK-5626.9
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)5.7
Liver13.25
Lung8.2
Lymphnode6.45
Lymphoma_burkitts(Daudi)10.2
Lymphoma_burkitts(Raji)11
MedullaOblongata7.1
OccipitalLobe7
OlfactoryBulb5.9
Ovary5.7
Pancreas6.25
PancreaticIslet8.25
ParietalLobe8.9
Pituitary8.85
Placenta7.4
Pons7.6
PrefrontalCortex9.4
Prostate8.85
Salivarygland6.45
SkeletalMuscle13.6
Skin7.25
SmoothMuscle8.6
Spinalcord8.3
SubthalamicNucleus7.45
SuperiorCervicalGanglion13.35
TemporalLobe7.25
Testis6.7
TestisGermCell5.9
TestisIntersitial6.6
TestisLeydigCell7.95
TestisSeminiferousTubule6.7
Thalamus7.95
Thymus5.7
Thyroid8.95
Tongue8.8
Tonsil7.6
Trachea6.5
TrigeminalGanglion9.75
Uterus5.9
UterusCorpus8
WholeBlood8.5
Wholebrain6.55
colon7.9
pineal_day9.2
pineal_night8.92
retina9.375
small_intestine7.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10057_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.22 ± 0.47
Basal Forebrain7.23 ± 0.16
Basal Part of Pons7.18 ± 0.76
Cerebellar Cortex6.74 ± 0.37
Cerebellar Nuclei7.26 ± 0.58
Claustrum6.82 ± 1.19
Epithalamus7.03 ± 1.05
Frontal Lobe7.29 ± 0.63
Globus Pallidus6.55 ± 0.75
Hypothalamus7.79 ± 0.8
Insula7.49 ± 0.24
Limbic Lobe6.59 ± 0.83
Mesencephalon7.14 ± 0.74
Myelencephalon7.06 ± 0.62
Occipital Lobe6.43 ± 0.9
Parietal Lobe7.18 ± 0.64
Pontine Tegmentum7.15 ± 0.5
Striatum5.5 ± 0.96
Subthalamus6.66 ± 0.42
Temporal Lobe7.56 ± 0.48
Thalamus6.91 ± 0.53
White Matter6.93 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sytl2CBCerebellum16.98
20.74
Sytl2CTXCerebral cortex66.83
63.6
Sytl2HIPHippocampal region18.37
22.55
Sytl2HPFHippocampal formation29.69
31.2
Sytl2HYHypothalamus16.4
13.68
Sytl2LSXLateral septal complex16.34
12.37
Sytl2MBMidbrain35.21
34.99
Sytl2MYMedulla33.63
38.86
Sytl2OLFOlfactory bulb35.19
29.14
Sytl2PPons31.15
35.98
Sytl2PALPallidum17.93
15.96
Sytl2RHPRetrohippocampal region50.39
44.75
Sytl2sAMYStriatum-like amygdalar nuclei13.17
9.75
Sytl2STRStriatum15.09
11.91
Sytl2STRdStriatum dorsal region15.18
12.49
Sytl2STRvStriatum ventral region15.47
11.3
Sytl2THThalamus22.36
20.6
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01429752 11 735 745 TAPVALEAENR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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