AutismKB 2.0

Annotation Detail for WDR55


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Basic Information Top
Gene Symbol:WDR55 ( FLJ20195,FLJ21702 )
Gene Full Name: WD repeat domain 55
Band: 5q31.3
Quick LinksEntrez ID:54853; OMIM: NA; Uniprot ID:WDR55_HUMAN; ENSEMBL ID: ENSG00000120314; HGNC ID: 25971
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus4 / 5640127
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor15 / 26384556
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal64 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood4 / 12347832
bone2 / 7165527
bone marrow1 / 4880120
brain26 / 110098923
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus2 / 2020998
eye2 / 2110549
heart0 / 896260 
intestine11 / 23447246
kidney9 / 21177742
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph2 / 4427045
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate6 / 18934531
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach1 / 9661910
testis2 / 3304426
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 222114_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.65
Adipocyte3.65
AdrenalCortex5.65
Adrenalgland3.1
Amygdala3.75
Appendix3.65
AtrioventricularNode3.35
BDCA4+_DentriticCells4.6
Bonemarrow3.6
BronchialEpithelialCells3.7
CD105+_Endothelial3.75
CD14+_Monocytes3.95
CD19+_BCells(neg._sel.)4.05
CD33+_Myeloid4.8
CD34+4.8
CD4+_Tcells4.65
CD56+_NKCells4.8
CD71+_EarlyErythroid3.45
CD8+_Tcells3.75
CardiacMyocytes4.65
Caudatenucleus3.25
Cerebellum3.2
CerebellumPeduncles4.1
CiliaryGanglion2.55
CingulateCortex3.75
Colorectaladenocarcinoma3.65
DorsalRootGanglion2.75
FetalThyroid3.6
Fetalbrain4.1
Fetalliver3.15
Fetallung3.1
GlobusPallidus3.15
Heart4.6
Hypothalamus4.05
Kidney2.9
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)5.65
Liver4.8
Lung4.65
Lymphnode6.35
Lymphoma_burkitts(Daudi)4.65
Lymphoma_burkitts(Raji)5.1
MedullaOblongata3.35
OccipitalLobe3.3
OlfactoryBulb3.2
Ovary2.4
Pancreas2.95
PancreaticIslet4.7
ParietalLobe3.95
Pituitary5.45
Placenta4.15
Pons3.6
PrefrontalCortex4.55
Prostate4.45
Salivarygland2.9
SkeletalMuscle4.2
Skin2.8
SmoothMuscle4.25
Spinalcord3.85
SubthalamicNucleus4.4
SuperiorCervicalGanglion4.1
TemporalLobe3.35
Testis3.2
TestisGermCell3.15
TestisIntersitial3.1
TestisLeydigCell3.65
TestisSeminiferousTubule3.15
Thalamus3.7
Thymus2.95
Thyroid4.6
Tongue4.2
Tonsil3.8
Trachea4.4
TrigeminalGanglion3.65
Uterus2.95
UterusCorpus3.25
WholeBlood4
Wholebrain3.15
colon3.6
pineal_day4.56
pineal_night4.44
retina4.425
small_intestine3.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P200549
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.82 ± 0.41
Basal Forebrain6.03 ± 0.29
Basal Part of Pons6.19 ± 0.26
Cerebellar Cortex6.13 ± 0.25
Cerebellar Nuclei6.26 ± 0.3
Claustrum5.91 ± 0.41
Epithalamus5.79 ± 0.35
Frontal Lobe5.95 ± 0.34
Globus Pallidus5.88 ± 0.41
Hypothalamus5.74 ± 0.66
Insula5.89 ± 0.3
Limbic Lobe5.85 ± 0.39
Mesencephalon5.89 ± 0.39
Myelencephalon5.9 ± 0.39
Occipital Lobe6.04 ± 0.31
Parietal Lobe6.01 ± 0.33
Pontine Tegmentum5.82 ± 0.42
Striatum5.56 ± 0.34
Subthalamus5.94 ± 0.01
Temporal Lobe5.95 ± 0.3
Thalamus5.94 ± 0.29
White Matter6.73 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr55CBCerebellum0.94
0.98
Wdr55CTXCerebral cortex0.52
0.4
Wdr55HIPHippocampal region1.57
1.42
Wdr55HPFHippocampal formation1.52
1.27
Wdr55HYHypothalamus0.41
0.41
Wdr55LSXLateral septal complex0.03
0
Wdr55MBMidbrain0.57
0.9
Wdr55MYMedulla2.05
2.94
Wdr55OLFOlfactory bulb2.33
2.34
Wdr55PPons1.85
2.85
Wdr55PALPallidum0.27
0.26
Wdr55RHPRetrohippocampal region1.21
0.77
Wdr55sAMYStriatum-like amygdalar nuclei0.51
0.61
Wdr55STRStriatum0.46
0.41
Wdr55STRdStriatum dorsal region0.24
0.19
Wdr55STRvStriatum ventral region1.32
1.12
Wdr55THThalamus0.8
0.73
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003120 21 288 308 GSVGQHTGEPVEELALSHCGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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