AutismKB 2.0

Annotation Detail for FAM46C


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:FAM46C ( FLJ20202 )
Gene Full Name: family with sequence similarity 46, member C
Band: 1p12
Quick LinksEntrez ID:54855; OMIM: NA; Uniprot ID:FA46C_HUMAN; ENSEMBL ID: ENSG00000183508; HGNC ID: 24712
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus24 / 56401242
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal129 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood14 / 123478113
bone0 / 716550 
bone marrow2 / 4880140
brain6 / 11009895
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart1 / 8962611
intestine10 / 23447242
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung12 / 33697435
lymph0 / 442700 
lymph node6 / 9161065
mammary gland13 / 15327184
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland4 / 16585241
placenta3 / 28082510
prostate3 / 18934515
salivary gland1 / 2015549
skin1 / 2105744
spleen4 / 5395274
stomach7 / 9661972
testis15 / 33044245
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea16 / 52413305
umbilical cord1 / 1368073
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220306_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.45
AdrenalCortex4.75
Adrenalgland3.9
Amygdala4.65
Appendix4.7
AtrioventricularNode4.05
BDCA4+_DentriticCells99.05
Bonemarrow108.6
BronchialEpithelialCells4.3
CD105+_Endothelial16.35
CD14+_Monocytes4.8
CD19+_BCells(neg._sel.)278.3
CD33+_Myeloid5.7
CD34+12.35
CD4+_Tcells36.9
CD56+_NKCells151.45
CD71+_EarlyErythroid355.65
CD8+_Tcells39.9
CardiacMyocytes7.8
Caudatenucleus4.05
Cerebellum3.65
CerebellumPeduncles5.25
CiliaryGanglion4
CingulateCortex4.7
Colorectaladenocarcinoma4.6
DorsalRootGanglion3.5
FetalThyroid4.85
Fetalbrain4.45
Fetalliver72.95
Fetallung3.65
GlobusPallidus4.3
Heart6.45
Hypothalamus4.9
Kidney3.85
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)3.6
Liver6.1
Lung5.05
Lymphnode6.05
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4.1
OccipitalLobe4.15
OlfactoryBulb3.6
Ovary3.1
Pancreas3.7
PancreaticIslet5.25
ParietalLobe4.9
Pituitary5.25
Placenta4.6
Pons4.35
PrefrontalCortex5.55
Prostate5.2
Salivarygland4.4
SkeletalMuscle10.35
Skin3.85
SmoothMuscle5.1
Spinalcord4.8
SubthalamicNucleus4.15
SuperiorCervicalGanglion7.15
TemporalLobe4.2
Testis501.25
TestisGermCell242.7
TestisIntersitial387.35
TestisLeydigCell136.15
TestisSeminiferousTubule163.7
Thalamus4.65
Thymus3.5
Thyroid5.65
Tongue4.5
Tonsil5.95
Trachea43.1
TrigeminalGanglion6.95
Uterus3.65
UterusCorpus4.1
WholeBlood4.95
Wholebrain3.75
colon4.75
pineal_day6.92
pineal_night5.44
retina5.475
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P137751
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.4 ± 1.06
Basal Forebrain2.2 ± 0.29
Basal Part of Pons1.78 ± 0.61
Cerebellar Cortex1.93 ± 0.79
Cerebellar Nuclei2.28 ± 0.68
Claustrum2.83 ± 0.8
Epithalamus1.71 ± 0.79
Frontal Lobe1.81 ± 0.6
Globus Pallidus2.56 ± 0.67
Hypothalamus1.98 ± 0.67
Insula1.79 ± 0.62
Limbic Lobe2.01 ± 0.65
Mesencephalon2.13 ± 0.66
Myelencephalon2.02 ± 0.67
Occipital Lobe2.28 ± 0.94
Parietal Lobe1.91 ± 0.63
Pontine Tegmentum2.03 ± 0.67
Striatum2.29 ± 0.79
Subthalamus2.48 ± 1
Temporal Lobe1.86 ± 0.58
Thalamus1.94 ± 0.61
White Matter2.42 ± 0.33
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved