AutismKB 2.0

Annotation Detail for GON4L


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Basic Information Top
Gene Symbol:GON4L ( DKFZp761I241,FLJ12923,FLJ20203,FLJ23040,GON-4,GON4,KIAA1606,MGC138817,MGC138818,RP11-243J18.4 )
Gene Full Name: gon-4-like (C. elegans)
Band: 1q22
Quick LinksEntrez ID:54856; OMIM: 610393; Uniprot ID:GON4L_HUMAN; ENSEMBL ID: ENSG00000116580; HGNC ID: 25973
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult105 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor11 / 94178116
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor13 / 26384549
glioma6 / 10688356
head and neck tumor10 / 13630273
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal122 / 336030736
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer3 / 10268029
retinoblastoma6 / 46356129
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood4 / 12347832
bone1 / 7165513
bone marrow2 / 4880140
brain38 / 110098934
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye16 / 21105475
heart2 / 8962622
intestine9 / 23447238
kidney13 / 21177761
larynx0 / 241450 
liver9 / 20774343
lung11 / 33697432
lymph1 / 4427022
lymph node7 / 9161076
mammary gland13 / 15327184
mouth6 / 6705289
muscle0 / 1077150 
nerve1 / 1576863
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta9 / 28082532
prostate9 / 18934547
salivary gland2 / 2015599
skin4 / 21057418
spleen3 / 5395255
stomach10 / 96619103
testis14 / 33044242
thymus3 / 8113136
thyroid6 / 47473126
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218873_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.5
Adipocyte4.85
AdrenalCortex5.15
Adrenalgland4.3
Amygdala6.2
Appendix6.3
AtrioventricularNode3.8
BDCA4+_DentriticCells6.3
Bonemarrow5.2
BronchialEpithelialCells9.75
CD105+_Endothelial5.4
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid10.2
CD34+6.7
CD4+_Tcells13.95
CD56+_NKCells14.75
CD71+_EarlyErythroid4.95
CD8+_Tcells14.75
CardiacMyocytes10.65
Caudatenucleus6.1
Cerebellum4.25
CerebellumPeduncles5.9
CiliaryGanglion2.8
CingulateCortex4.95
Colorectaladenocarcinoma5.25
DorsalRootGanglion3.7
FetalThyroid11.45
Fetalbrain6.5
Fetalliver6.8
Fetallung4.5
GlobusPallidus3.7
Heart6.4
Hypothalamus6.3
Kidney4.25
Leukemia_chronicMyelogenousK-56235
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)15.75
Liver6.75
Lung8.2
Lymphnode10.6
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)8.25
MedullaOblongata4.5
OccipitalLobe4.7
OlfactoryBulb4.05
Ovary3.35
Pancreas4.15
PancreaticIslet5.55
ParietalLobe6.2
Pituitary7.2
Placenta6
Pons4.85
PrefrontalCortex6.15
Prostate6.65
Salivarygland3.95
SkeletalMuscle5.85
Skin3.95
SmoothMuscle11.05
Spinalcord5.6
SubthalamicNucleus4.1
SuperiorCervicalGanglion5.55
TemporalLobe4.55
Testis7.2
TestisGermCell4.35
TestisIntersitial4.35
TestisLeydigCell7.3
TestisSeminiferousTubule10.2
Thalamus5.25
Thymus7.75
Thyroid6.55
Tongue4.9
Tonsil5.35
Trachea4.25
TrigeminalGanglion4.65
Uterus4.35
UterusCorpus4.8
WholeBlood5.85
Wholebrain5
colon4.9
pineal_day6.34
pineal_night6.12
retina6.475
small_intestine4.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P85862
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.76 ± 0.32
Basal Forebrain5.96 ± 0.2
Basal Part of Pons6.03 ± 0.38
Cerebellar Cortex6.22 ± 0.36
Cerebellar Nuclei5.53 ± 0.51
Claustrum5.57 ± 0.72
Epithalamus7.04 ± 0.64
Frontal Lobe6.03 ± 0.4
Globus Pallidus5.94 ± 0.22
Hypothalamus5.97 ± 0.42
Insula6.09 ± 0.31
Limbic Lobe5.8 ± 0.41
Mesencephalon5.91 ± 0.49
Myelencephalon5.89 ± 0.46
Occipital Lobe5.85 ± 0.43
Parietal Lobe5.91 ± 0.41
Pontine Tegmentum5.93 ± 0.43
Striatum5.8 ± 0.44
Subthalamus5.99 ± 0.31
Temporal Lobe5.93 ± 0.37
Thalamus6 ± 0.41
White Matter6.04 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
5830417I10RikCBCerebellum24.57
30.42
5830417I10RikCTXCerebral cortex94.99
74.27
5830417I10RikHIPHippocampal region59.03
92.33
5830417I10RikHPFHippocampal formation69.02
83.03
5830417I10RikHYHypothalamus26.4
20.87
5830417I10RikLSXLateral septal complex24.71
16.82
5830417I10RikMBMidbrain32.88
30.85
5830417I10RikMYMedulla25.22
25.48
5830417I10RikOLFOlfactory bulb56.96
46.36
5830417I10RikPPons22.78
23.24
5830417I10RikPALPallidum21.57
19.32
5830417I10RikRHPRetrohippocampal region88.68
73.96
5830417I10RiksAMYStriatum-like amygdalar nuclei45.14
32.73
5830417I10RikSTRStriatum24.7
17.26
5830417I10RikSTRdStriatum dorsal region22.22
15.42
5830417I10RikSTRvStriatum ventral region22.86
15.65
5830417I10RikTHThalamus46.28
42.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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