AutismKB 2.0

Annotation Detail for TMEM214


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Basic Information Top
Gene Symbol:TMEM214 ( FLJ20254,FLJ39682 )
Gene Full Name: transmembrane protein 214
Band: 2p23.3
Quick LinksEntrez ID:54867; OMIM: NA; Uniprot ID:TM214_HUMAN; ENSEMBL ID: ENSG00000119777; HGNC ID: 25983
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus31 / 56401254
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult466 / 1939121240
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma16 / 82823193
colorectal tumor19 / 114246166
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor11 / 26384541
glioma12 / 106883112
head and neck tumor27 / 136302198
kidney tumor7 / 68959101
leukemia10 / 95842104
liver tumor9 / 9635993
lung tumor8 / 10312777
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal206 / 336030761
ovarian tumor16 / 76682208
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer309 / 1026803009
retinoblastoma0 / 463560 
skin tumor26 / 124949208
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites5 / 40015124
bladder0 / 297570 
blood11 / 12347889
bone7 / 7165597
bone marrow2 / 4880140
brain48 / 110098943
cervix4 / 4817183
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus1 / 2020949
eye11 / 21105452
heart7 / 8962678
intestine32 / 234472136
kidney17 / 21177780
larynx5 / 24145207
liver11 / 20774352
lung33 / 33697497
lymph1 / 4427022
lymph node5 / 9161054
mammary gland12 / 15327178
mouth9 / 67052134
muscle3 / 10771527
nerve2 / 15768126
ovary18 / 102051176
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta30 / 280825106
prostate319 / 1893451684
salivary gland2 / 2015599
skin35 / 210574166
spleen7 / 53952129
stomach7 / 9661972
testis6 / 33044218
thymus6 / 8113173
thyroid12 / 47473252
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus23 / 23287898
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217899_at
Cell line Expression level Expression bar
721_B_lymphoblasts396.65
Adipocyte185.85
AdrenalCortex204.45
Adrenalgland184.3
Amygdala119.8
Appendix137.3
AtrioventricularNode84.05
BDCA4+_DentriticCells332.1
Bonemarrow169.3
BronchialEpithelialCells176.4
CD105+_Endothelial109.35
CD14+_Monocytes176.75
CD19+_BCells(neg._sel.)152.1
CD33+_Myeloid238.15
CD34+199.45
CD4+_Tcells173.3
CD56+_NKCells220.1
CD71+_EarlyErythroid117.65
CD8+_Tcells146.3
CardiacMyocytes238.9
Caudatenucleus112.9
Cerebellum126
CerebellumPeduncles152
CiliaryGanglion101.2
CingulateCortex190.3
Colorectaladenocarcinoma233.5
DorsalRootGanglion87.9
FetalThyroid170.6
Fetalbrain101.45
Fetalliver114.8
Fetallung123.85
GlobusPallidus80.9
Heart161.5
Hypothalamus132
Kidney128.8
Leukemia_chronicMyelogenousK-562284.3
Leukemia_promyelocytic-HL-6098.05
Leukemialymphoblastic(MOLT-4)89.9
Liver303
Lung209.45
Lymphnode182.45
Lymphoma_burkitts(Daudi)201.4
Lymphoma_burkitts(Raji)239.65
MedullaOblongata104.95
OccipitalLobe93.45
OlfactoryBulb106.35
Ovary155.3
Pancreas150.05
PancreaticIslet315.4
ParietalLobe139.2
Pituitary248.45
Placenta375.3
Pons97.9
PrefrontalCortex204.4
Prostate200.85
Salivarygland157.2
SkeletalMuscle193.05
Skin100.55
SmoothMuscle398.05
Spinalcord120
SubthalamicNucleus126.1
SuperiorCervicalGanglion236.5
TemporalLobe101.35
Testis152.1
TestisGermCell132.95
TestisIntersitial111
TestisLeydigCell199.05
TestisSeminiferousTubule137.8
Thalamus133.2
Thymus125.45
Thyroid331.65
Tongue107.6
Tonsil184.1
Trachea201.5
TrigeminalGanglion111.55
Uterus121.6
UterusCorpus143.85
WholeBlood120.4
Wholebrain91.25
colon133.9
pineal_day136.68
pineal_night137.48
retina197.825
small_intestine112.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P143083
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.8 ± 0.65
Basal Forebrain3.79 ± 0.48
Basal Part of Pons3.8 ± 0.56
Cerebellar Cortex3.82 ± 0.54
Cerebellar Nuclei3.81 ± 0.53
Claustrum3.98 ± 0.92
Epithalamus3.54 ± 0.62
Frontal Lobe3.78 ± 0.54
Globus Pallidus3.68 ± 0.79
Hypothalamus3.74 ± 0.43
Insula3.77 ± 0.6
Limbic Lobe3.73 ± 0.6
Mesencephalon3.8 ± 0.73
Myelencephalon3.84 ± 0.59
Occipital Lobe3.8 ± 0.7
Parietal Lobe3.69 ± 0.59
Pontine Tegmentum3.6 ± 0.51
Striatum3.63 ± 0.65
Subthalamus3.65 ± 0.3
Temporal Lobe3.72 ± 0.59
Thalamus3.83 ± 0.61
White Matter3.98 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1110039B18RikCBCerebellum14.5
15.03
1110039B18RikCTXCerebral cortex47.17
31.82
1110039B18RikHIPHippocampal region36.75
41.6
1110039B18RikHPFHippocampal formation35.71
33.6
1110039B18RikHYHypothalamus15.52
10.47
1110039B18RikLSXLateral septal complex15.05
9.14
1110039B18RikMBMidbrain17.74
14.1
1110039B18RikMYMedulla19.76
18.75
1110039B18RikOLFOlfactory bulb32.86
22.47
1110039B18RikPPons15.75
14.12
1110039B18RikPALPallidum13.09
9.47
1110039B18RikRHPRetrohippocampal region34.98
25.16
1110039B18RiksAMYStriatum-like amygdalar nuclei17.57
11.1
1110039B18RikSTRStriatum16.45
10.54
1110039B18RikSTRdStriatum dorsal region18.05
11.93
1110039B18RikSTRvStriatum ventral region11.43
6.67
1110039B18RikTHThalamus16.71
13.07
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00081495 16 47 62 YDLTPAIQTTSTLYER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018