AutismKB 2.0

Annotation Detail for CASZ1


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Basic Information Top
Gene Symbol:CASZ1 ( CST,FLJ12223,FLJ20321,SRG,ZNF693,dJ734G22.1 )
Gene Full Name: castor zinc finger 1
Band: 1p36.22
Quick LinksEntrez ID:54897; OMIM: 609895; Uniprot ID:CASZ1_HUMAN; ENSEMBL ID: ENSG00000130940; HGNC ID: 26002
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal89 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye21 / 21105499
heart0 / 896260 
intestine9 / 23447238
kidney3 / 21177714
larynx0 / 241450 
liver4 / 20774319
lung12 / 33697435
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate6 / 18934531
salivary gland0 / 201550 
skin21 / 21057499
spleen0 / 539520 
stomach7 / 9661972
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220015_at
Cell line Expression level Expression bar
721_B_lymphoblasts26.6
Adipocyte22.25
AdrenalCortex30.35
Adrenalgland13.15
Amygdala22.9
Appendix22.85
AtrioventricularNode17.55
BDCA4+_DentriticCells28
Bonemarrow22.1
BronchialEpithelialCells29.7
CD105+_Endothelial24.75
CD14+_Monocytes43.75
CD19+_BCells(neg._sel.)25.95
CD33+_Myeloid53.7
CD34+28.95
CD4+_Tcells31.2
CD56+_NKCells27.25
CD71+_EarlyErythroid21.4
CD8+_Tcells22.05
CardiacMyocytes28.6
Caudatenucleus16.5
Cerebellum18.35
CerebellumPeduncles26.2
CiliaryGanglion14.7
CingulateCortex16.05
Colorectaladenocarcinoma23.45
DorsalRootGanglion17.1
FetalThyroid23.55
Fetalbrain19.95
Fetalliver19.7
Fetallung19.35
GlobusPallidus14.1
Heart28.65
Hypothalamus20.6
Kidney15.25
Leukemia_chronicMyelogenousK-56220.4
Leukemia_promyelocytic-HL-6020.1
Leukemialymphoblastic(MOLT-4)18.3
Liver26.95
Lung41
Lymphnode22.5
Lymphoma_burkitts(Daudi)28.65
Lymphoma_burkitts(Raji)34.35
MedullaOblongata20.75
OccipitalLobe17.7
OlfactoryBulb18
Ovary15
Pancreas19.4
PancreaticIslet23
ParietalLobe24
Pituitary33.2
Placenta15.9
Pons21.35
PrefrontalCortex21.05
Prostate44.25
Salivarygland18.15
SkeletalMuscle22.1
Skin17.25
SmoothMuscle25.6
Spinalcord21.85
SubthalamicNucleus16.4
SuperiorCervicalGanglion31.85
TemporalLobe20.6
Testis19.85
TestisGermCell22.1
TestisIntersitial19.05
TestisLeydigCell22.5
TestisSeminiferousTubule19.5
Thalamus22.85
Thymus17.9
Thyroid25.8
Tongue22.3
Tonsil30.65
Trachea21.15
TrigeminalGanglion24.45
Uterus18.4
UterusCorpus29.65
WholeBlood24.65
Wholebrain17.6
colon24.25
pineal_day33.2
pineal_night32.54
retina25.75
small_intestine22
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P201295
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.56 ± 0.64
Basal Forebrain5.17 ± 0.2
Basal Part of Pons5.2 ± 0.35
Cerebellar Cortex4.93 ± 0.32
Cerebellar Nuclei5.4 ± 0.41
Claustrum5.92 ± 0.71
Epithalamus5.04 ± 0.34
Frontal Lobe5.19 ± 0.57
Globus Pallidus5.8 ± 0.24
Hypothalamus5.18 ± 0.32
Insula4.92 ± 0.38
Limbic Lobe5.38 ± 0.53
Mesencephalon5.37 ± 0.44
Myelencephalon5.3 ± 0.54
Occipital Lobe5.39 ± 0.59
Parietal Lobe5.28 ± 0.43
Pontine Tegmentum5.2 ± 0.51
Striatum5.48 ± 0.47
Subthalamus4.9 ± 0.36
Temporal Lobe5.24 ± 0.5
Thalamus5.3 ± 0.44
White Matter5.38 ± 0.76
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Casz1CBCerebellum32.97
49.68
Casz1CTXCerebral cortex68.06
58.4
Casz1HIPHippocampal region39.58
55.57
Casz1HPFHippocampal formation40.13
48.39
Casz1HYHypothalamus9.41
7.03
Casz1LSXLateral septal complex8.58
6.26
Casz1MBMidbrain19.66
17.58
Casz1MYMedulla20.13
21.33
Casz1OLFOlfactory bulb55.85
53.24
Casz1PPons15.91
16.54
Casz1PALPallidum24.68
24.8
Casz1RHPRetrohippocampal region38.51
36.07
Casz1sAMYStriatum-like amygdalar nuclei67.41
63.42
Casz1STRStriatum43.16
36.5
Casz1STRdStriatum dorsal region44.16
37.07
Casz1STRvStriatum ventral region46.41
37.6
Casz1THThalamus22.63
22.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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