Annotation Detail for HEATR2
Basic Information Top
| Gene Symbol: | HEATR2 ( FLJ20397,FLJ25564,FLJ31671,FLJ39381 ) |
|---|---|
| Gene Full Name: | HEAT repeat containing 2 |
| Band: | 7p22.3 |
| Quick Links | Entrez ID:54919; OMIM: NA; Uniprot ID:HEAT2_HUMAN; ENSEMBL ID: ENSG00000164818; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.535896
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 20 / 564012 | 35 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 55 / 1939121 | 28 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 11 / 263845 | 41 | |
| glioma | 6 / 106883 | 56 | |
| head and neck tumor | 1 / 136302 | 7 |  |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 7 / 95842 | 73 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 107 / 3360307 | 31 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 12 / 104616 | 114 | |
| primitive neuroectodermal tumor of the CNS | 15 / 125680 | 119 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 31 / 1100989 | 28 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 13 / 215722 | 60 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 18 / 211054 | 85 | |
| heart | 5 / 89626 | 55 | |
| intestine | 8 / 234472 | 34 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 0 / 24145 | 0 | |
| liver | 4 / 207743 | 19 | |
| lung | 8 / 336974 | 23 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 15 / 210574 | 71 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 10 / 330442 | 30 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218460_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 91.95 | |
| Adipocyte | 42.35 | |
| AdrenalCortex | 43.8 | |
| Adrenalgland | 36.55 | |
| Amygdala | 43.45 | |
| Appendix | 52.4 | |
| AtrioventricularNode | 33.7 | |
| BDCA4+_DentriticCells | 45.1 | |
| Bonemarrow | 49.2 | |
| BronchialEpithelialCells | 104.1 | |
| CD105+_Endothelial | 129.15 | |
| CD14+_Monocytes | 40.8 | |
| CD19+_BCells(neg._sel.) | 42.2 | |
| CD33+_Myeloid | 49.45 | |
| CD34+ | 70.8 | |
| CD4+_Tcells | 47.1 | |
| CD56+_NKCells | 38.95 | |
| CD71+_EarlyErythroid | 38.5 | |
| CD8+_Tcells | 30.15 | |
| CardiacMyocytes | 53.2 | |
| Caudatenucleus | 38.6 | |
| Cerebellum | 35.7 | |
| CerebellumPeduncles | 48.8 | |
| CiliaryGanglion | 32.75 | |
| CingulateCortex | 42.65 | |
| Colorectaladenocarcinoma | 85.7 | |
| DorsalRootGanglion | 33.15 | |
| FetalThyroid | 46.2 | |
| Fetalbrain | 43.3 | |
| Fetalliver | 46.9 | |
| Fetallung | 37.45 | |
| GlobusPallidus | 30.6 | |
| Heart | 71.1 | |
| Hypothalamus | 47.15 | |
| Kidney | 35 | |
| Leukemia_chronicMyelogenousK-562 | 68.75 | |
| Leukemia_promyelocytic-HL-60 | 59.05 | |
| Leukemialymphoblastic(MOLT-4) | 37.2 | |
| Liver | 58.2 | |
| Lung | 65.8 | |
| Lymphnode | 43.7 | |
| Lymphoma_burkitts(Daudi) | 117.3 | |
| Lymphoma_burkitts(Raji) | 105.2 | |
| MedullaOblongata | 39.45 | |
| OccipitalLobe | 35.5 | |
| OlfactoryBulb | 34.9 | |
| Ovary | 28.7 | |
| Pancreas | 34.5 | |
| PancreaticIslet | 51.1 | |
| ParietalLobe | 44.45 | |
| Pituitary | 72.45 | |
| Placenta | 47.6 | |
| Pons | 40.9 | |
| PrefrontalCortex | 53.85 | |
| Prostate | 69.35 | |
| Salivarygland | 37.2 | |
| SkeletalMuscle | 49.1 | |
| Skin | 33.7 | |
| SmoothMuscle | 48.3 | |
| Spinalcord | 45.5 | |
| SubthalamicNucleus | 39.5 | |
| SuperiorCervicalGanglion | 52.05 | |
| TemporalLobe | 40.05 | |
| Testis | 49.05 | |
| TestisGermCell | 36.4 | |
| TestisIntersitial | 30.95 | |
| TestisLeydigCell | 42.45 | |
| TestisSeminiferousTubule | 40.75 | |
| Thalamus | 43.25 | |
| Thymus | 57.5 | |
| Thyroid | 61.55 | |
| Tongue | 43 | |
| Tonsil | 44.5 | |
| Trachea | 35.95 | |
| TrigeminalGanglion | 48.7 | |
| Uterus | 43.3 | |
| UterusCorpus | 39.15 | |
| WholeBlood | 35.5 | |
| Wholebrain | 39.95 | |
| colon | 43.55 | |
| pineal_day | 26.78 | |
| pineal_night | 27.38 | |
| retina | 54.85 | |
| small_intestine | 42 | |
- Probe name: CUST_1897_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.64 ± 0.67 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.3 ± 0.57 | |
| Basal Part of Pons | 4.04 ± 0.49 | |
| Cerebellar Cortex | 4.04 ± 0.54 | |
| Cerebellar Nuclei | 3.62 ± 0.69 | |
| Claustrum | 4.46 ± 0.63 | |
| Epithalamus | 4.99 ± 0.69 | |
| Frontal Lobe | 3.85 ± 0.64 | |
| Globus Pallidus | 4.83 ± 0.56 | |
| Hypothalamus | 4.07 ± 0.51 | |
| Insula | 3.95 ± 0.73 | |
| Limbic Lobe | 4.35 ± 0.55 | |
| Mesencephalon | 4.16 ± 0.63 | |
| Myelencephalon | 4.21 ± 0.61 | |
| Occipital Lobe | 4.65 ± 0.6 | |
| Parietal Lobe | 4.21 ± 0.53 | |
| Pontine Tegmentum | 4.23 ± 0.67 | |
| Striatum | 4.64 ± 0.46 | |
| Subthalamus | 3.59 ± 0.23 | |
| Temporal Lobe | 4.13 ± 0.53 | |
| Thalamus | 4.29 ± 0.45 | |
| White Matter | 5.34 ± 0.59 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Heatr2 | CB | Cerebellum | 27.89 | |
| 30.41 | | |||
| Heatr2 | CTX | Cerebral cortex | 73.35 | |
| 50.37 | | |||
| Heatr2 | HIP | Hippocampal region | 42.81 | |
| 50.84 | | |||
| Heatr2 | HPF | Hippocampal formation | 47.16 | |
| 47.02 | | |||
| Heatr2 | HY | Hypothalamus | 27.38 | |
| 22.84 | | |||
| Heatr2 | LSX | Lateral septal complex | 18.25 | |
| 12.21 | | |||
| Heatr2 | MB | Midbrain | 23.51 | |
| 20.38 | | |||
| Heatr2 | MY | Medulla | 33.58 | |
| 35.25 | | |||
| Heatr2 | OLF | Olfactory bulb | 74.01 | |
| 59.05 | | |||
| Heatr2 | P | Pons | 29.19 | |
| 31 | | |||
| Heatr2 | PAL | Pallidum | 18.79 | |
| 15.95 | | |||
| Heatr2 | RHP | Retrohippocampal region | 58.74 | |
| 43.53 | | |||
| Heatr2 | sAMY | Striatum-like amygdalar nuclei | 20.81 | |
| 14.18 | | |||
| Heatr2 | STR | Striatum | 22.02 | |
| 15.85 | | |||
| Heatr2 | STRd | Striatum dorsal region | 15.8 | |
| 11.44 | | |||
| Heatr2 | STRv | Striatum ventral region | 43.34 | |
| 29.7 | | |||
| Heatr2 | TH | Thalamus | 29.29 | |
| 23.38 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| HEAT2_HUMAN_2 | 28 | 2 | 29 | AALGVAEAVAAPHPAEGAETAEAVELSR | PRIDE |
| PAp00063577 | 20 | 56 | 75 | ALEEPGPAADPTAFQGPWAR | Peptide Atlas |