AutismKB 2.0

Annotation Detail for LIME1


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Basic Information Top
Gene Symbol:LIME1 ( FLJ20406,LIME,LP8067,dJ583P15.4 )
Gene Full Name: Lck interacting transmembrane adaptor 1
Band: 20q13.33
Quick LinksEntrez ID:54923; OMIM: 609809; Uniprot ID:LIME1_HUMAN; ENSEMBL ID: ENSG00000203896; HGNC ID: 26016
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal70 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood9 / 12347872
bone0 / 716550 
bone marrow0 / 488010 
brain12 / 110098910
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine3 / 23447212
kidney18 / 21177784
larynx0 / 241450 
liver6 / 20774328
lung2 / 3369745
lymph1 / 4427022
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach8 / 9661982
testis3 / 3304429
thymus3 / 8113136
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219541_at
Cell line Expression level Expression bar
721_B_lymphoblasts240.45
Adipocyte173.75
AdrenalCortex197.3
Adrenalgland146.5
Amygdala166.85
Appendix148.75
AtrioventricularNode130.25
BDCA4+_DentriticCells1464.3
Bonemarrow171.6
BronchialEpithelialCells158.75
CD105+_Endothelial139.6
CD14+_Monocytes140.75
CD19+_BCells(neg._sel.)169.05
CD33+_Myeloid144.1
CD34+153.25
CD4+_Tcells1097.2
CD56+_NKCells492.1
CD71+_EarlyErythroid148
CD8+_Tcells610.3
CardiacMyocytes208
Caudatenucleus183.25
Cerebellum138.8
CerebellumPeduncles277.8
CiliaryGanglion120.75
CingulateCortex183.05
Colorectaladenocarcinoma244.15
DorsalRootGanglion128.9
FetalThyroid180.7
Fetalbrain168.1
Fetalliver164.45
Fetallung118.1
GlobusPallidus124.55
Heart222.35
Hypothalamus173.5
Kidney326.4
Leukemia_chronicMyelogenousK-562198.1
Leukemia_promyelocytic-HL-60167.6
Leukemialymphoblastic(MOLT-4)325.45
Liver1629.75
Lung184.5
Lymphnode194.9
Lymphoma_burkitts(Daudi)216.15
Lymphoma_burkitts(Raji)275.1
MedullaOblongata166.5
OccipitalLobe150.35
OlfactoryBulb150.45
Ovary127.75
Pancreas151.6
PancreaticIslet198.35
ParietalLobe199.45
Pituitary247.4
Placenta163.5
Pons192.55
PrefrontalCortex201.85
Prostate198.3
Salivarygland131.2
SkeletalMuscle199.1
Skin122.95
SmoothMuscle176.55
Spinalcord182.2
SubthalamicNucleus186.95
SuperiorCervicalGanglion176.1
TemporalLobe186.7
Testis139.65
TestisGermCell133.4
TestisIntersitial137.75
TestisLeydigCell162.05
TestisSeminiferousTubule190.9
Thalamus183.7
Thymus480.05
Thyroid201.9
Tongue164.45
Tonsil163.65
Trachea128.5
TrigeminalGanglion155
Uterus124.1
UterusCorpus158.7
WholeBlood638.35
Wholebrain125.1
colon118.9
pineal_day167.28
pineal_night154.02
retina174.825
small_intestine111.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12765_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.01 ± 0.64
Basal Forebrain7.21 ± 0.21
Basal Part of Pons7.23 ± 0.49
Cerebellar Cortex6.5 ± 0.26
Cerebellar Nuclei7.94 ± 0.56
Claustrum7.69 ± 0.58
Epithalamus6.22 ± 0.68
Frontal Lobe7.07 ± 0.56
Globus Pallidus8.46 ± 0.38
Hypothalamus6.8 ± 0.67
Insula6.69 ± 0.58
Limbic Lobe6.93 ± 0.57
Mesencephalon7.32 ± 0.57
Myelencephalon7.14 ± 0.66
Occipital Lobe6.9 ± 0.65
Parietal Lobe7.15 ± 0.53
Pontine Tegmentum7.11 ± 0.53
Striatum7.36 ± 0.58
Subthalamus7.73 ± 0.28
Temporal Lobe6.94 ± 0.6
Thalamus7.46 ± 0.41
White Matter8.05 ± 0.8
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018